New software tool decodes cytokine 'language' of immune cells

by Julie Parry,Yale School of MedicineOverview of the CINEMA-OT framework. a, scRNA-seq count data is first decomposed into confounder variation and treatment-associated variation using ICA. Cel

Updated on: January 04,2024 15

New software tool decodes cytokine 'language' of immune cells

by Julie Parry,Yale School of MedicineOverview of the CINEMA-OT framework. a, scRNA-seq count data is first decomposed into confounder variation and treatment-associated variation using ICA. Cel

Updated on:January 04,2024 15

Longitudinal characterization of behavioral, morphological and transcriptomic changes in a tauopathy mouse model

by Impact Journals LLCGene expression profiling revealed various patterns of changes in PFC and hippocampus of P301S mice at different ages. Credit:Aging(2023). DOI: 10.18632/aging.205057A

Updated on: January 10,2024 17

Longitudinal characterization of behavioral, morphological and transcriptomic changes in a tauopathy mouse model

by Impact Journals LLCGene expression profiling revealed various patterns of changes in PFC and hippocampus of P301S mice at different ages. Credit:Aging(2023). DOI: 10.18632/aging.205057A

Updated on:January 10,2024 17

Lifespan increases in mice when specific brain cells are activated, study finds

by Julia Evangelou Strait,Washington University School of MedicineWith age, the researchers found that the protein Ppp1r17 tends to leave the nucleus of the neurons, and when that happens, the n

Updated on: January 09,2024 13

Lifespan increases in mice when specific brain cells are activated, study finds

by Julia Evangelou Strait,Washington University School of MedicineWith age, the researchers found that the protein Ppp1r17 tends to leave the nucleus of the neurons, and when that happens, the n

Updated on:January 09,2024 13

FDA approves iloprost for severe frostbite

by Physician's Briefing StaffAurlumyn (iloprost), a vasodilator, has been approved by the U.S. Food and Drug Administration to treat severe frostbite. The injected medication lowers the risk for f

Updated on: March 22,2024 12

FDA approves iloprost for severe frostbite

by Physician's Briefing StaffAurlumyn (iloprost), a vasodilator, has been approved by the U.S. Food and Drug Administration to treat severe frostbite. The injected medication lowers the risk for f

Updated on:March 22,2024 12

New wound healing research produces full thickness human bioprinted skin

byAtrium Health Wake Forest BaptistWFIRM researchers use cells and hydrogels as bioinks to 3D print human skin. Credit: Wake Forest Institute for Regenerative MedicineA research paper published

Updated on: January 06,2024 6

New wound healing research produces full thickness human bioprinted skin

byAtrium Health Wake Forest BaptistWFIRM researchers use cells and hydrogels as bioinks to 3D print human skin. Credit: Wake Forest Institute for Regenerative MedicineA research paper published

Updated on:January 06,2024 6

Use of anticoagulant drug after aortic valve replacement lowers mortality risk, study finds

by ByJay Furst,Mayo ClinicGraphical abstract. Credit:Mayo Clinic Proceedings(2023). DOI: 10.1016/j.mayocp.2023.08.012Patients who received the anticoagulant drug warfarin after biopr

Updated on: January 26,2024 7

Use of anticoagulant drug after aortic valve replacement lowers mortality risk, study finds

by ByJay Furst,Mayo ClinicGraphical abstract. Credit:Mayo Clinic Proceedings(2023). DOI: 10.1016/j.mayocp.2023.08.012Patients who received the anticoagulant drug warfarin after biopr

Updated on:January 26,2024 7

EU watchdog backs anti-bilharzia parasite treatment for kids

Credit: Pixabay/CC0 Public DomainThe world's first medicine formulated to treat a damaging tropical parasite infection in preschool children received the green light Friday from Europe's drug

Updated on: January 26,2024 15

EU watchdog backs anti-bilharzia parasite treatment for kids

Credit: Pixabay/CC0 Public DomainThe world's first medicine formulated to treat a damaging tropical parasite infection in preschool children received the green light Friday from Europe's drug

Updated on:January 26,2024 15

Wastewater sequencing reveals community and variant dynamics of the collective human virome

by Ana María S. Rodríguez,Baylor College of MedicineStudy sites, capture, and viral diversity. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-42064-1In the not-so-distan

Updated on: December 28,2023 12

Wastewater sequencing reveals community and variant dynamics of the collective human virome

by Ana María S. Rodríguez,Baylor College of MedicineStudy sites, capture, and viral diversity. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-42064-1In the not-so-distan

Updated on:December 28,2023 12

Researchers develop innovative and flexible method to study immune cell capabilities

byNational University of SingaporeSchematic of PAINTKiller assay. a, Preparation of affinity matrix on effector cells. Effector cells were first labeled with anti-CD45 conjugated with streptavid

Updated on: December 30,2023 16

Researchers develop innovative and flexible method to study immune cell capabilities

byNational University of SingaporeSchematic of PAINTKiller assay. a, Preparation of affinity matrix on effector cells. Effector cells were first labeled with anti-CD45 conjugated with streptavid

Updated on:December 30,2023 16

Study suggests key to antipsychotic-drug–induced obesity

by UTSouthwestern Medical CenterEffect of risperidone and risperidone + LepAb on body weight, food intake, and glucose tolerance. Female mice (n = 9) were placed on an HFD alone (Ctrl) or a

Updated on: January 26,2024 8

Study suggests key to antipsychotic-drug–induced obesity

by UTSouthwestern Medical CenterEffect of risperidone and risperidone + LepAb on body weight, food intake, and glucose tolerance. Female mice (n = 9) were placed on an HFD alone (Ctrl) or a

Updated on:January 26,2024 8

Dos and don'ts developed for direct oral anticoagulants

by Brigham and Women’s HospitalCentral Illustration. Credit:Journal of the American College of Cardiology(2024). DOI: 10.1016/j.jacc.2023.10.038Direct oral anticoagulants (DOACs) are

Updated on: May 09,2024 4

Dos and don'ts developed for direct oral anticoagulants

by Brigham and Women’s HospitalCentral Illustration. Credit:Journal of the American College of Cardiology(2024). DOI: 10.1016/j.jacc.2023.10.038Direct oral anticoagulants (DOACs) are

Updated on:May 09,2024 4

Study reveals insights into diabetic kidney disease and how anti-obesity drugs work

by Monash UniversityThis image shows a cross section of a kidney. Credit: Holly Fischer/WikipediaData from Australian researchers could partly explain why a trial of a new drug for diabetes, was

Updated on: January 26,2024 5

Study reveals insights into diabetic kidney disease and how anti-obesity drugs work

by Monash UniversityThis image shows a cross section of a kidney. Credit: Holly Fischer/WikipediaData from Australian researchers could partly explain why a trial of a new drug for diabetes, was

Updated on:January 26,2024 5