Genesiology
BioMarin's Dwarfism Therapy Gets FDA Nod for Expanded Use

BioMarin's Dwarfism Therapy Gets FDA Nod for Expanded Use

By Pratik JainOctober23,2023(Reuters) - The U.S. health regulator on Friday approved the expanded use of BioMarin Pharmaceutical's once-daily injection to treat children under the age
Genetics October 25,2023 30
BioMarin's Dwarfism Therapy Gets FDA Nod for Expanded Use

BioMarin's Dwarfism Therapy Gets FDA Nod for Expanded Use

By Pratik JainOctober23,2023(Reuters) - The U.S. health regulator on Friday approved the expanded use of BioMarin Pharmaceutical's once-daily injection to treat children under the age
Genetics October 25,2023 30
In Down syndrome cells, genome-wide disruptions mimic a senescence-like state

In Down syndrome cells, genome-wide disruptions mimic a senescence-like state

Extra chromosome alters chromosomal conformation and DNA accessibility in neural progenitor cells; study establishes senescence as a potentially targetable mechanism for future treatment.David Orenste
Genetics October 11,2023 60
In Down syndrome cells, genome-wide disruptions mimic a senescence-like state

In Down syndrome cells, genome-wide disruptions mimic a senescence-like state

Extra chromosome alters chromosomal conformation and DNA accessibility in neural progenitor cells; study establishes senescence as a potentially targetable mechanism for future treatment.David Orenste
Genetics October 11,2023 60
Programmable DNA hydrogels for advanced cell culture and personalized medicine

Programmable DNA hydrogels for advanced cell culture and personalized medicine

byLeibniz Institute for Polymer ResearchCredit: Elisha Krieg and Yu-Hsuan PengIn-vitro culture of biological cells plays an important role in advancing biological research. However, currently av
Genetics October 11,2023 135
Programmable DNA hydrogels for advanced cell culture and personalized medicine

Programmable DNA hydrogels for advanced cell culture and personalized medicine

byLeibniz Institute for Polymer ResearchCredit: Elisha Krieg and Yu-Hsuan PengIn-vitro culture of biological cells plays an important role in advancing biological research. However, currently av
Genetics October 11,2023 135
Scientists alter genes of innate immune cells with DNA-snipping tool

Scientists alter genes of innate immune cells with DNA-snipping tool

by Sarah C.p. Williams,University of California, Los AngelesCredit: CC0 Public DomainA UCLA research team has successfully used the powerful gene-editing tool known as CRISPR-Cas9 to alter the D
Genetics October 11,2023 239
Scientists alter genes of innate immune cells with DNA-snipping tool

Scientists alter genes of innate immune cells with DNA-snipping tool

by Sarah C.p. Williams,University of California, Los AngelesCredit: CC0 Public DomainA UCLA research team has successfully used the powerful gene-editing tool known as CRISPR-Cas9 to alter the D
Genetics October 11,2023 239
Gene editing system restores dystrophin function in stem cells from patients with Duchenne muscular

Gene editing system restores dystrophin function in stem cells from patients with Duchenne muscular

Gene editing system restores dystrophin function in stem cells from patients with Duchenne muscular dystrophybyCell PressThis photo shows green dystrophin protein restored by dual-Cas3 in skelet
Genesiology October 28,2023 8
Gene editing system restores dystrophin function in stem cells from patients with Duchenne muscular

Gene editing system restores dystrophin function in stem cells from patients with Duchenne muscular

Gene editing system restores dystrophin function in stem cells from patients with Duchenne muscular dystrophybyCell PressThis photo shows green dystrophin protein restored by dual-Cas3 in skelet
Genesiology October 28,2023 8
Researchers discover first-ever link between hemoglobin-like protein and normal heart development

Researchers discover first-ever link between hemoglobin-like protein and normal heart development

by University of Maryland School of Medicinecygb2mutant phenotype presents organ laterality defects.aCRISPR/Cas9 mediated genome editing ofcygb2. Two different gRNA were t
Genetics February 19,2024 7
Researchers discover first-ever link between hemoglobin-like protein and normal heart development

Researchers discover first-ever link between hemoglobin-like protein and normal heart development

by University of Maryland School of Medicinecygb2mutant phenotype presents organ laterality defects.aCRISPR/Cas9 mediated genome editing ofcygb2. Two different gRNA were t
Genetics February 19,2024 7
Assisted reproductive technology not tied to higher BMI in childhood, finds study

Assisted reproductive technology not tied to higher BMI in childhood, finds study

by Lori SolomonCredit: CC0 Public DomainBeing born after assisted reproductive technology (ART) is not associated with higher body mass index (BMI) at age 5 to 8 years, according to a study published
Genesiology December 28,2023 20
Assisted reproductive technology not tied to higher BMI in childhood, finds study

Assisted reproductive technology not tied to higher BMI in childhood, finds study

by Lori SolomonCredit: CC0 Public DomainBeing born after assisted reproductive technology (ART) is not associated with higher body mass index (BMI) at age 5 to 8 years, according to a study published
Genesiology December 28,2023 20
How one of the X chromosomes in female embryonic stem cells is silenced

How one of the X chromosomes in female embryonic stem cells is silenced

by Kelly Malcom,University of MichiganAnalysis of XIST RNA coating during differentiation of female hESCs. a Schematic of hESC differentiation into embryoid bodies (EBs) with three different med
Genetics October 11,2023 192
How one of the X chromosomes in female embryonic stem cells is silenced

How one of the X chromosomes in female embryonic stem cells is silenced

by Kelly Malcom,University of MichiganAnalysis of XIST RNA coating during differentiation of female hESCs. a Schematic of hESC differentiation into embryoid bodies (EBs) with three different med
Genetics October 11,2023 192
Developing deep learning models to understand the human genome

Developing deep learning models to understand the human genome

by Olivia Dimmer,Northwestern UniversityDeveloping deep learning models to identify polyA sites at nucleotide-level resolution and calculate polyA site strength. Credit:Nature Communicatio
Genetics February 19,2024 8
Developing deep learning models to understand the human genome

Developing deep learning models to understand the human genome

by Olivia Dimmer,Northwestern UniversityDeveloping deep learning models to identify polyA sites at nucleotide-level resolution and calculate polyA site strength. Credit:Nature Communicatio
Genetics February 19,2024 8
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