Anti-aging drug rapamycin found to improve immune function through endolysosomes

by Max Planck SocietyRapamycin is one of the most promising anti-aging substances to date. Rapamycin is named after "Rapa Nui," the local translation for the Easter Islands, where the a

Updated on: April 02,2024 11

Anti-aging drug rapamycin found to improve immune function through endolysosomes

by Max Planck SocietyRapamycin is one of the most promising anti-aging substances to date. Rapamycin is named after "Rapa Nui," the local translation for the Easter Islands, where the a

Updated on:April 02,2024 11

A new vision for AAV-delivered gene therapies

by Benjamin Boettner,Harvard UniversityAAVs with TLR9-inhibitory sequences incorporated into their genomes allowed significantly higher expression of a linked fluorescent reporter gene in the mo

Updated on: April 02,2024 14

A new vision for AAV-delivered gene therapies

by Benjamin Boettner,Harvard UniversityAAVs with TLR9-inhibitory sequences incorporated into their genomes allowed significantly higher expression of a linked fluorescent reporter gene in the mo

Updated on:April 02,2024 14

3-D printed pill samples gut microbiome to aid diagnosis and treatment

by Tufts UniversityBacteria in the gut are pulled into the helical channels by an osmotic 'pump' in the pill. Credit: Nano Lab, Tufts UniversityA research team led by Tufts University eng

Updated on: April 02,2024 12

3-D printed pill samples gut microbiome to aid diagnosis and treatment

by Tufts UniversityBacteria in the gut are pulled into the helical channels by an osmotic 'pump' in the pill. Credit: Nano Lab, Tufts UniversityA research team led by Tufts University eng

Updated on:April 02,2024 12

Clinical presentation of IDDMSSD syndrome likely associated with molecular location of mutation in PAK1 gene

by Texas Children's HospitalCredit: Pixabay/CC0 Public DomainA recent study from Texas Children's Hospital and Baylor College of Medicine has expanded the clinical spectrum of a new epileptic

Updated on: April 01,2024 0

Clinical presentation of IDDMSSD syndrome likely associated with molecular location of mutation in PAK1 gene

by Texas Children's HospitalCredit: Pixabay/CC0 Public DomainA recent study from Texas Children's Hospital and Baylor College of Medicine has expanded the clinical spectrum of a new epileptic

Updated on:April 01,2024 0

New insight into old IBD drug could improve treatments

by Jim Schnabel,Cornell UniversityGraphical Abstract. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.xcrm.2024.101431Although it is one of the oldest medications used to treat pa

Updated on: March 30,2024 13

New insight into old IBD drug could improve treatments

by Jim Schnabel,Cornell UniversityGraphical Abstract. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.xcrm.2024.101431Although it is one of the oldest medications used to treat pa

Updated on:March 30,2024 13

Team assesses biological functions, diseases and therapeutic targets of heat shock protein 90

by Sichuan International Medical Exchange and Promotion AssociationHSP90 chaperone undergoes dynamic cycling process: HSP90 transits between open and closed states to promote maturation of polypeptide

Updated on: March 30,2024 0

Team assesses biological functions, diseases and therapeutic targets of heat shock protein 90

by Sichuan International Medical Exchange and Promotion AssociationHSP90 chaperone undergoes dynamic cycling process: HSP90 transits between open and closed states to promote maturation of polypeptide

Updated on:March 30,2024 0

Familial Alzheimer's disease transferred via bone marrow transplant in mice

byCell PressA painting representing Alzheimer's transmissibility as reported in thisStem Cell Reportsstudy. Credit: Chaahat SinghFamilial Alzheimer's disease can be transferr

Updated on: March 30,2024 0

Familial Alzheimer's disease transferred via bone marrow transplant in mice

byCell PressA painting representing Alzheimer's transmissibility as reported in thisStem Cell Reportsstudy. Credit: Chaahat SinghFamilial Alzheimer's disease can be transferr

Updated on:March 30,2024 0

Scientists develop 'safe' bone grafts from cow bones to heal bone fractures and injuries

byUniversity of SharjahRepresentative images of immunohistochemical staining of DMB and DCC implantation sites to visualize the intensity distribution of osteogenic factors. Credit:PLOS ON

Updated on: March 30,2024 0

Scientists develop 'safe' bone grafts from cow bones to heal bone fractures and injuries

byUniversity of SharjahRepresentative images of immunohistochemical staining of DMB and DCC implantation sites to visualize the intensity distribution of osteogenic factors. Credit:PLOS ON

Updated on:March 30,2024 0

Researchers create real-time view of placental development in mice

by Michaela Martinez,Duke UniversityCredit: Duke UniversityPhysicians and biomedical engineers at Duke University have developed a method to visualize the growth of a placenta throughout a mouse

Updated on: March 30,2024 0

Researchers create real-time view of placental development in mice

by Michaela Martinez,Duke UniversityCredit: Duke UniversityPhysicians and biomedical engineers at Duke University have developed a method to visualize the growth of a placenta throughout a mouse

Updated on:March 30,2024 0

Skeleton-wide study of blood cell formation offers new ways to treat blood cancers, infections

byCincinnati Children's Hospital Medical CenterHow the number of production sites in the sternum can vary significantly by the type of stress on the system, such as blood loss, infection, ca

Updated on: March 30,2024 0

Skeleton-wide study of blood cell formation offers new ways to treat blood cancers, infections

byCincinnati Children's Hospital Medical CenterHow the number of production sites in the sternum can vary significantly by the type of stress on the system, such as blood loss, infection, ca

Updated on:March 30,2024 0

Better cancer trials could be around the corner

by Cold Spring Harbor LaboratoryCredit: Pixabay/CC0 Public DomainCold Spring Harbor Laboratory Associate Professor and Cancer Center member Tobias Janowitz led aCOVID-19 clinical trial&nbsp

Updated on: March 30,2024 18

Better cancer trials could be around the corner

by Cold Spring Harbor LaboratoryCredit: Pixabay/CC0 Public DomainCold Spring Harbor Laboratory Associate Professor and Cancer Center member Tobias Janowitz led aCOVID-19 clinical trial&nbsp

Updated on:March 30,2024 18

Researchers describe tools to better understand CaMKII, a protein involved in brain and heart disease

by CU Anschutz Medical CampusOptogenetic tools for monitoring and controlling CaMKII activation(A) Camui is a FRET-based sensor that detects conformational changes in CaMKII upon activation. An N

Updated on: March 30,2024 10

Researchers describe tools to better understand CaMKII, a protein involved in brain and heart disease

by CU Anschutz Medical CampusOptogenetic tools for monitoring and controlling CaMKII activation(A) Camui is a FRET-based sensor that detects conformational changes in CaMKII upon activation. An N

Updated on:March 30,2024 10