Researchers are building detailed maps of colorectal cancer to better understand the dynamics of the disease

Researchers are building detailed maps of colorectal cancer to better understand the dynamics of the disease

by Harvard Medical SchoolA 3D reconstruction of colorectal cancer revealed that what was once thought to be 2D mucin pools with clusters of cancer cells floating inside is actually a complex and

Researchers are building detailed maps of colorectal cancer to better understand the dynamics of the disease

by Harvard Medical SchoolA 3D reconstruction of colorectal cancer revealed that what was once thought to be 2D mucin pools with clusters of cancer cells floating inside is actually a complex and
Inhibiting the biological crosstalk of autophagy and mitochondrial function underlying pancreatic ductal adenocarcinoma

Inhibiting the biological crosstalk of autophagy and mitochondrial function underlying pancreatic ductal adenocarcinoma

by Thamarasee Jeewandara , Medical XpressAutophagy inhibition leads to a drop in the LIP in PDAC. (A) Autophagy was inhibited genetically or pharmacologically in PDAC cells, and the relative LIP was d

Inhibiting the biological crosstalk of autophagy and mitochondrial function underlying pancreatic ductal adenocarcinoma

by Thamarasee Jeewandara , Medical XpressAutophagy inhibition leads to a drop in the LIP in PDAC. (A) Autophagy was inhibited genetically or pharmacologically in PDAC cells, and the relative LIP was d
Study offers new understanding of why kidney cancers become metastatic

Study offers new understanding of why kidney cancers become metastatic

by University of Texas M. D. Anderson Cancer CenterThis image shows a cross section of a kidney. Credit: Holly Fischer/WikipediaResearchers at The University of Texas MD Anderson Cancer have engi

Study offers new understanding of why kidney cancers become metastatic

by University of Texas M. D. Anderson Cancer CenterThis image shows a cross section of a kidney. Credit: Holly Fischer/WikipediaResearchers at The University of Texas MD Anderson Cancer have engi
Antitumor cell activity in glioblastoma regulated by inhibiting triggering receptor expressed on myeloid cells 2

Antitumor cell activity in glioblastoma regulated by inhibiting triggering receptor expressed on myeloid cells 2

by Thamarasee Jeewandara , Medical XpressTREM2 expression is higher in GBM tumors than normal brain tissue and inversely correlates with patient outcome. (A) Box plots of TREM2 expression in IDH1/2–wi

Antitumor cell activity in glioblastoma regulated by inhibiting triggering receptor expressed on myeloid cells 2

by Thamarasee Jeewandara , Medical XpressTREM2 expression is higher in GBM tumors than normal brain tissue and inversely correlates with patient outcome. (A) Box plots of TREM2 expression in IDH1/2–wi
Study shows the benefit of harnessing the body's own immune cells to fight brain cancer

Study shows the benefit of harnessing the body's own immune cells to fight brain cancer

by Salk InstituteCredit: Human Brain ProjectGlioblastoma, the most common and deadly form of brain cancer, grows rapidly to invade and destroy healthy brain tissue. The tumor sends out cancerous

Study shows the benefit of harnessing the body's own immune cells to fight brain cancer

by Salk InstituteCredit: Human Brain ProjectGlioblastoma, the most common and deadly form of brain cancer, grows rapidly to invade and destroy healthy brain tissue. The tumor sends out cancerous
Researchers identify a protein that promotes cancer metastasis, providing a new potential treatment target

Researchers identify a protein that promotes cancer metastasis, providing a new potential treatment target

by City University of Hong KongThey also demonstrated that LH1 could bind and stabilize Septin2 (SEPT2), a protein that plays an essential role in preparing the cells for high mechanical migratio

Researchers identify a protein that promotes cancer metastasis, providing a new potential treatment target

by City University of Hong KongThey also demonstrated that LH1 could bind and stabilize Septin2 (SEPT2), a protein that plays an essential role in preparing the cells for high mechanical migratio
A new tool for diagnosing cancer: Platform combines structural details with molecular information about a tumor

A new tool for diagnosing cancer: Platform combines structural details with molecular information about a tumor

by Harvard Medical SchoolThe Orion tool combines molecular details revealed by immunofluorescence imaging (left) with structural information gained through traditional histology staining (middle)

A new tool for diagnosing cancer: Platform combines structural details with molecular information about a tumor

by Harvard Medical SchoolThe Orion tool combines molecular details revealed by immunofluorescence imaging (left) with structural information gained through traditional histology staining (middle)
Electrical detection of RNA cancer biomarkers at the single-molecule level

Electrical detection of RNA cancer biomarkers at the single-molecule level

by Thamarasee Jeewandara , Medical XpressDetection of cancer biomarkers using the STMBJ single-molecule conductance approach. (a) Liquid biopsy samples contain circulating nucleic acids that can be de

Electrical detection of RNA cancer biomarkers at the single-molecule level

by Thamarasee Jeewandara , Medical XpressDetection of cancer biomarkers using the STMBJ single-molecule conductance approach. (a) Liquid biopsy samples contain circulating nucleic acids that can be de
Researchers circumvent radiation resistance in subtype of brain tumors

Researchers circumvent radiation resistance in subtype of brain tumors

by University of MichiganMutant IDH1 glioma invading the normal brain structures. Non-tumor astrocytes are stained using an anti-GFAP antibody and are seen in brown. Credit: Maria Castro, Ph.D.It

Researchers circumvent radiation resistance in subtype of brain tumors

by University of MichiganMutant IDH1 glioma invading the normal brain structures. Non-tumor astrocytes are stained using an anti-GFAP antibody and are seen in brown. Credit: Maria Castro, Ph.D.It
New insights into liver cancer using organoids

New insights into liver cancer using organoids

by Princess Máxima Center for Pediatric OncologyA culture of mini livers. Credit: Benedetta Artegiani / Princess Máxima Center for pediatric oncologyScientists of the Princess Máxima Center for pediat

New insights into liver cancer using organoids

by Princess Máxima Center for Pediatric OncologyA culture of mini livers. Credit: Benedetta Artegiani / Princess Máxima Center for pediatric oncologyScientists of the Princess Máxima Center for pediat