Little-studied RNA might be key to regulating genetic disorders like epilepsy and autism

byNorthwestern UniversityA hairpin loop from a pre-mRNA. Highlighted are the nucleobases (green) and the ribose-phosphate backbone (blue). Note that this is a single strand of RNA that folds bac

Updated on: October 31,2024 0

Little-studied RNA might be key to regulating genetic disorders like epilepsy and autism

byNorthwestern UniversityA hairpin loop from a pre-mRNA. Highlighted are the nucleobases (green) and the ribose-phosphate backbone (blue). Note that this is a single strand of RNA that folds bac

Updated on:October 31,2024 0

Researchers uncover novel role of protein GPNMB in heart repair

byUniversity of California, Los AngelesHeart muscle cells surrounding the damaged tissue after a heart attack. Credit: Arjun Deb Lab/UCLAUCLA scientists have identified the protein GPNMB as a cr

Updated on: October 31,2024 0

Researchers uncover novel role of protein GPNMB in heart repair

byUniversity of California, Los AngelesHeart muscle cells surrounding the damaged tissue after a heart attack. Credit: Arjun Deb Lab/UCLAUCLA scientists have identified the protein GPNMB as a cr

Updated on:October 31,2024 0

Gene expression in early pregnancy could contribute to sex-based health differences

byCedars-Sinai Medical CenterSample cohorts and quality control.ASummary of the first trimester placenta cohorts and analyses. F = females, M = males.BPrincipal component

Updated on: October 31,2024 0

Gene expression in early pregnancy could contribute to sex-based health differences

byCedars-Sinai Medical CenterSample cohorts and quality control.ASummary of the first trimester placenta cohorts and analyses. F = females, M = males.BPrincipal component

Updated on:October 31,2024 0

Novel gene discovery paves the way for treating central nervous system injuries

byHong Kong University of Science and TechnologyLipin1 KD facilitates robust CST axon regeneration after complete spinal cord injury. Credit: HKUSTA collaborative study in neuroscience, spearhea

Updated on: October 31,2024 0

Novel gene discovery paves the way for treating central nervous system injuries

byHong Kong University of Science and TechnologyLipin1 KD facilitates robust CST axon regeneration after complete spinal cord injury. Credit: HKUSTA collaborative study in neuroscience, spearhea

Updated on:October 31,2024 0

Genetic variants in melatonin receptor linked to idiopathic osteoporosis

by Justin Jackson , Medical XpressCredit: cottonbro studio from PexelsColumbia University Medical Center researchers have identified specific variants in a melatonin receptor gene that impair bone tur

Updated on: October 31,2024 0

Genetic variants in melatonin receptor linked to idiopathic osteoporosis

by Justin Jackson , Medical XpressCredit: cottonbro studio from PexelsColumbia University Medical Center researchers have identified specific variants in a melatonin receptor gene that impair bone tur

Updated on:October 31,2024 0

CRISPR-Cas9 gene editing trial results support further development as treatment for hereditary angioedema

byAmsterdam University Medical CentersCredit: Pixabay/CC0 Public DomainA single treatment with a CRISPR-Cas9 based gene editing therapy is enough to replace the daily medication of patients with

Updated on: October 31,2024 0

CRISPR-Cas9 gene editing trial results support further development as treatment for hereditary angioedema

byAmsterdam University Medical CentersCredit: Pixabay/CC0 Public DomainA single treatment with a CRISPR-Cas9 based gene editing therapy is enough to replace the daily medication of patients with

Updated on:October 31,2024 0

Shoring up the heart muscle's intricately designed structures to treat heart failure

by Nancy Fliesler,Children's Hospital BostonGene therapy could potentially restore the orderly structure of dyads in heart muscle (as in the top image) and help reverse heart failure. Credit

Updated on: October 31,2024 0

Shoring up the heart muscle's intricately designed structures to treat heart failure

by Nancy Fliesler,Children's Hospital BostonGene therapy could potentially restore the orderly structure of dyads in heart muscle (as in the top image) and help reverse heart failure. Credit

Updated on:October 31,2024 0

Ancient viral DNA in the human genome linked to multiple sclerosis and amyotrophic lateral sclerosis

byKing's College LondonRetrotranscriptome-wide association studies of neurodegenerative diseases. Credit:Brain, Behavior, and Immunity(2024). DOI: 10.1016/j.bbi.2024.10.020New re

Updated on: October 31,2024 0

Ancient viral DNA in the human genome linked to multiple sclerosis and amyotrophic lateral sclerosis

byKing's College LondonRetrotranscriptome-wide association studies of neurodegenerative diseases. Credit:Brain, Behavior, and Immunity(2024). DOI: 10.1016/j.bbi.2024.10.020New re

Updated on:October 31,2024 0

Gene technology detects more conditions than standard newborn screening, study finds

byColumbia University Irving Medical CenterCredit: Unsplash/CC0 Public DomainEarly results from a study of newborn screening methods show that DNA analysis picks up many more preventable or trea

Updated on: October 31,2024 0

Gene technology detects more conditions than standard newborn screening, study finds

byColumbia University Irving Medical CenterCredit: Unsplash/CC0 Public DomainEarly results from a study of newborn screening methods show that DNA analysis picks up many more preventable or trea

Updated on:October 31,2024 0

Researchers develop new tool to predict the impact of genetic variants

byBrigham and Women’s HospitalCredit: Pixabay/CC0 Public DomainA studypublishedin the journalCell Genomicsintroduces a new tool called FUSE (Functional Substitution Estim

Updated on: October 31,2024 0

Researchers develop new tool to predict the impact of genetic variants

byBrigham and Women’s HospitalCredit: Pixabay/CC0 Public DomainA studypublishedin the journalCell Genomicsintroduces a new tool called FUSE (Functional Substitution Estim

Updated on:October 31,2024 0

Consortium creates a robust, open-access platform to define the clinical relevance of genes and variants

by Molly Chiu,Baylor College of MedicineCredit:Genetics in Medicine(2024). DOI: 10.1016/j.gim.2024.101228The Clinical Genome Resource (ClinGen), a resource that works to define the c

Updated on: October 31,2024 0

Consortium creates a robust, open-access platform to define the clinical relevance of genes and variants

by Molly Chiu,Baylor College of MedicineCredit:Genetics in Medicine(2024). DOI: 10.1016/j.gim.2024.101228The Clinical Genome Resource (ClinGen), a resource that works to define the c

Updated on:October 31,2024 0

Plastic chemical phthalate causes DNA breakage and chromosome defects in sex cells, new study finds

byPublic Library of ScienceBBP exposure causes chromosome organization defects in the female germline. Carnoy's fixed and DAPI-stained images of gonads at the pachytene stage following expos

Updated on: October 31,2024 0

Plastic chemical phthalate causes DNA breakage and chromosome defects in sex cells, new study finds

byPublic Library of ScienceBBP exposure causes chromosome organization defects in the female germline. Carnoy's fixed and DAPI-stained images of gonads at the pachytene stage following expos

Updated on:October 31,2024 0