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Noncoding RNA Terc-53 and hyaluronan receptor Hmmr regulate aging in mice

Noncoding RNA Terc-53 and hyaluronan receptor Hmmr regulate aging in mice

by Higher Education PressTerc-53 functions as a molecular scaffold bringing together Hmmr and Trim25, accelerating Hmmr's ubiquitination-mediated degradation, which consequently leads to neuroinfl

Noncoding RNA Terc-53 and hyaluronan receptor Hmmr regulate aging in mice

by Higher Education PressTerc-53 functions as a molecular scaffold bringing together Hmmr and Trim25, accelerating Hmmr's ubiquitination-mediated degradation, which consequently leads to neuroinfl
Epigenetics blood markers can help understand dementia risk

Epigenetics blood markers can help understand dementia risk

byUniversity of ExeterOverview of the model generation. The model generation workflow consists of model training in the EXTEND and EMIF-AD cohorts using two different approaches. Credit:Al

Epigenetics blood markers can help understand dementia risk

byUniversity of ExeterOverview of the model generation. The model generation workflow consists of model training in the EXTEND and EMIF-AD cohorts using two different approaches. Credit:Al
Trouble with trembling hands originates in the brain: Research IDs genetic variations associated with essential tremor

Trouble with trembling hands originates in the brain: Research IDs genetic variations associated with essential tremor

bySingHealthA neural pathway known as the "tremor network" regulates movement and runs between the motor cortex (A), thalamus (B) and cerebellum (C). Messages need to flow smoothly alo

Trouble with trembling hands originates in the brain: Research IDs genetic variations associated with essential tremor

bySingHealthA neural pathway known as the "tremor network" regulates movement and runs between the motor cortex (A), thalamus (B) and cerebellum (C). Messages need to flow smoothly alo
Experts reach consensus on gene therapy carcinogenicity risks

Experts reach consensus on gene therapy carcinogenicity risks

byMary Ann Liebert, IncCredit: CC0 Public DomainAnarticlein the journalHuman Gene Therapydescribes the consensus reached by invited experts who participated in a meeting

Experts reach consensus on gene therapy carcinogenicity risks

byMary Ann Liebert, IncCredit: CC0 Public DomainAnarticlein the journalHuman Gene Therapydescribes the consensus reached by invited experts who participated in a meeting
Trioxidized cysteine and aging: Beyond proteinopathic paradigms

Trioxidized cysteine and aging: Beyond proteinopathic paradigms

by Impact Journals LLCAnalysis of the levels of t-Cys residues in the circulating blood plasma platelet proteome of young and old subjects. (A) Average level of t-Cys residues in proteins, categorized

Trioxidized cysteine and aging: Beyond proteinopathic paradigms

by Impact Journals LLCAnalysis of the levels of t-Cys residues in the circulating blood plasma platelet proteome of young and old subjects. (A) Average level of t-Cys residues in proteins, categorized
Scientist discover rare genotype causing early menopause

Scientist discover rare genotype causing early menopause

by deCODE geneticsCredit: Nadezhda Moryak from PexelsScientists have identified a sequence variant in the CCDC201 gene that, when inherited from both parents homozygous, causes menopause on average ni

Scientist discover rare genotype causing early menopause

by deCODE geneticsCredit: Nadezhda Moryak from PexelsScientists have identified a sequence variant in the CCDC201 gene that, when inherited from both parents homozygous, causes menopause on average ni
BRCA1 gene mutation may increase the risk of impaired fertility, study shows

BRCA1 gene mutation may increase the risk of impaired fertility, study shows

byMonash University(a) Human cortical ovarian tissues from BRCA1 (n=8) and BRCA2 (n=10) mutation carriers (mc) were immunohistochemically stained for DDX4 as a marker of

BRCA1 gene mutation may increase the risk of impaired fertility, study shows

byMonash University(a) Human cortical ovarian tissues from BRCA1 (n=8) and BRCA2 (n=10) mutation carriers (mc) were immunohistochemically stained for DDX4 as a marker of
World first discoveries allow researchers to accurately diagnose prenatal exposure syndromes and birth disorders

World first discoveries allow researchers to accurately diagnose prenatal exposure syndromes and birth disorders

byLawson Health Research InstituteBlood testing using technology called EpiSign. Credit: London Health Sciences CentreResearchers at London Health Sciences Centre (LHSC) and Lawson Health Resear

World first discoveries allow researchers to accurately diagnose prenatal exposure syndromes and birth disorders

byLawson Health Research InstituteBlood testing using technology called EpiSign. Credit: London Health Sciences CentreResearchers at London Health Sciences Centre (LHSC) and Lawson Health Resear
Research team reveals how TREM2 genetic mutation affects late-onset Alzheimer's

Research team reveals how TREM2 genetic mutation affects late-onset Alzheimer's

byUniversity of California, IrvineMERFISH spatial transcriptomics enables spatial variation analysis of the transcriptome at the cell type level. A Dataset overview consisting of 15 samples, fro

Research team reveals how TREM2 genetic mutation affects late-onset Alzheimer's

byUniversity of California, IrvineMERFISH spatial transcriptomics enables spatial variation analysis of the transcriptome at the cell type level. A Dataset overview consisting of 15 samples, fro
Scientists outline key challenges and promising avenues in obesity genetics

Scientists outline key challenges and promising avenues in obesity genetics

byPennington Biomedical Research CenterCredit: Pixabay/CC0 Public DomainResearch on the genetics of obesity dates to the early 1920s, with many of the initial findings indicating the complexity

Scientists outline key challenges and promising avenues in obesity genetics

byPennington Biomedical Research CenterCredit: Pixabay/CC0 Public DomainResearch on the genetics of obesity dates to the early 1920s, with many of the initial findings indicating the complexity
Study finds omega-3 supplements reduce genetic risk of high total cholesterol, LDL and triglyceride levels

Study finds omega-3 supplements reduce genetic risk of high total cholesterol, LDL and triglyceride levels

byUniversity of GeorgiaCredit: Pixabay/CC0 Public DomainFish oil supplements are a multi-billion dollar industry in the U.S. and abroad, with about 2 out of every 25 people popping the popular o

Study finds omega-3 supplements reduce genetic risk of high total cholesterol, LDL and triglyceride levels

byUniversity of GeorgiaCredit: Pixabay/CC0 Public DomainFish oil supplements are a multi-billion dollar industry in the U.S. and abroad, with about 2 out of every 25 people popping the popular o