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Neurology
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Unraveling Alzheimer's catalysts as weavers of amyloid β fibrils

Unraveling Alzheimer's catalysts as weavers of amyloid β fibrils

by National Institutes of Natural Sciences(A) On the neuronal cell membrane, Aβ molecules adopt a "U"-shaped conformation, allining alternately on the membrane surface to form two layer

Unraveling Alzheimer's catalysts as weavers of amyloid β fibrils

by National Institutes of Natural Sciences(A) On the neuronal cell membrane, Aβ molecules adopt a "U"-shaped conformation, allining alternately on the membrane surface to form two layer
Untangling the role of tau in Alzheimer's disease

Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et

Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et
Revealing roles of dementia proteins in normal memory

Revealing roles of dementia proteins in normal memory

by Flinders UniversityGraphical abstract. Credit:The EMBO Journal(2022). DOI: 10.15252/embj.2021110242New research has revealed how the tau protein, a critical element in the formatio

Revealing roles of dementia proteins in normal memory

by Flinders UniversityGraphical abstract. Credit:The EMBO Journal(2022). DOI: 10.15252/embj.2021110242New research has revealed how the tau protein, a critical element in the formatio
Uncovering the unusual way aggregates hijack proteins

Uncovering the unusual way aggregates hijack proteins

by Utrecht University,Utrecht University Faculty of ScienceTau stacking. Credit: Stefan Rudiger - Utrecht UniversityUtrecht scientists have uncovered how aggregates alter the behavior of Tau pro

Uncovering the unusual way aggregates hijack proteins

by Utrecht University,Utrecht University Faculty of ScienceTau stacking. Credit: Stefan Rudiger - Utrecht UniversityUtrecht scientists have uncovered how aggregates alter the behavior of Tau pro
Decoding the genetics that drive disease

Decoding the genetics that drive disease

by University of South AustraliaSome human genes traditionally labeled as 'bad' are not always what they seem. Credit: Gerd Altmann from PixabayFrom Alzheimer's to obesity, life can c

Decoding the genetics that drive disease

by University of South AustraliaSome human genes traditionally labeled as 'bad' are not always what they seem. Credit: Gerd Altmann from PixabayFrom Alzheimer's to obesity, life can c
Uncovering the molecular mechanism behind synapse loss in Alzheimer's disease

Uncovering the molecular mechanism behind synapse loss in Alzheimer's disease

by Korea Brain Research InstituteCredit: Unsplash/CC0 Public DomainKorea Brain Research Institute (KBRI, Pann-Ghill Suh (President)) announced that Dr. Kea Joo Lee and Dr. You-Na Jang of the Neural Ci

Uncovering the molecular mechanism behind synapse loss in Alzheimer's disease

by Korea Brain Research InstituteCredit: Unsplash/CC0 Public DomainKorea Brain Research Institute (KBRI, Pann-Ghill Suh (President)) announced that Dr. Kea Joo Lee and Dr. You-Na Jang of the Neural Ci
Unraveling Alzheimer's: New study documents how brain cells go bad

Unraveling Alzheimer's: New study documents how brain cells go bad

by University of North Carolina Health CareNeurons treated with Alzheimer's-associated proteins exhibit drastic calcium increases (blue, green, yellow, red to white), and the cells form tau-f

Unraveling Alzheimer's: New study documents how brain cells go bad

by University of North Carolina Health CareNeurons treated with Alzheimer's-associated proteins exhibit drastic calcium increases (blue, green, yellow, red to white), and the cells form tau-f
Tdap vaccination tied to lower dementia risk in older adults

Tdap vaccination tied to lower dementia risk in older adults

Tetanus, diphtheria, pertussis (Tdap) vaccination in older adults is associated with a 42 percent lower dementia risk, according to a study recently published inTheJournals of Gerontology,

Tdap vaccination tied to lower dementia risk in older adults

Tetanus, diphtheria, pertussis (Tdap) vaccination in older adults is associated with a 42 percent lower dementia risk, according to a study recently published inTheJournals of Gerontology,
Brain network mechanism causing spatial memory impairment revealed

Brain network mechanism causing spatial memory impairment revealed

by University of California, IrvineNew study, led by UCI School of Medicine's Kei Igarashi, PhD, found that remapping of place cells, a brain circuit function to discriminate distinct environ

Brain network mechanism causing spatial memory impairment revealed

by University of California, IrvineNew study, led by UCI School of Medicine's Kei Igarashi, PhD, found that remapping of place cells, a brain circuit function to discriminate distinct environ
Tuberculosis vaccine lowers rates of Alzheimer's disease in cancer patients

Tuberculosis vaccine lowers rates of Alzheimer's disease in cancer patients

by Hebrew University of JerusalemCredit: CC0 Public DomainHolidays are a time for family. Festive gatherings with parents, grandparents, aunts and uncles create memories that last a lifetime. But

Tuberculosis vaccine lowers rates of Alzheimer's disease in cancer patients

by Hebrew University of JerusalemCredit: CC0 Public DomainHolidays are a time for family. Festive gatherings with parents, grandparents, aunts and uncles create memories that last a lifetime. But
Untangling APOE ε4's association to tau tangles

Untangling APOE ε4's association to tau tangles

by McGill UniversityCredit: CC0 Public DomainFor years, physicians have been aware that patients carrying the apolipoprotein E4 (APOEε4) gene are at a greater risk of developing Alzheimer's d

Untangling APOE ε4's association to tau tangles

by McGill UniversityCredit: CC0 Public DomainFor years, physicians have been aware that patients carrying the apolipoprotein E4 (APOEε4) gene are at a greater risk of developing Alzheimer's d
Untangling the brain: New research offers hope for Alzheimer's disease

Untangling the brain: New research offers hope for Alzheimer's disease

by Arizona State UniversityThe development of neurodegenerative pathology resulting from low levels of the protein Rbbp7 (on the left), compared with normal levels associated with a healthy brain

Untangling the brain: New research offers hope for Alzheimer's disease

by Arizona State UniversityThe development of neurodegenerative pathology resulting from low levels of the protein Rbbp7 (on the left), compared with normal levels associated with a healthy brain