Massive drug search uncovers infinitesimal molecule that kills cancers while sparing immune cells

by Delthia Ricks , Medical XpressN6F11 suppresses the growth of human PDAC. (A) PANC1 cells were pretreated with DMSO or N6F11 (5 µM) for 12 hours. (B) MiaPACA2 cells were pretreated with DMSO or N6F1

Updated on: December 30,2023

Massive drug search uncovers infinitesimal molecule that kills cancers while sparing immune cells

by Delthia Ricks , Medical XpressN6F11 suppresses the growth of human PDAC. (A) PANC1 cells were pretreated with DMSO or N6F11 (5 µM) for 12 hours. (B) MiaPACA2 cells were pretreated with DMSO or N6F1

Updated on:December 30,2023

Energy stress triggers PFKL-dependent lipid droplet-mitochondria tethering and β-oxidation to support tumor growth

Updated on: September 15,2024

Energy stress triggers PFKL-dependent lipid droplet-mitochondria tethering and β-oxidation to support tumor growth

Updated on:September 15,2024

CAR T cell therapy: On the cusp of 'an immunotherapy revolution'?

by Delthia Ricks , Medical XpressCancer cell during cell division. Credit: National Institutes of HealthA deeper understanding of the immune system's role in controlling cancer has helped drive &q

Updated on: April 09,2024

CAR T cell therapy: On the cusp of 'an immunotherapy revolution'?

by Delthia Ricks , Medical XpressCancer cell during cell division. Credit: National Institutes of HealthA deeper understanding of the immune system's role in controlling cancer has helped drive &q

Updated on:April 09,2024

The power of machine learning in prostate cancer imaging

by Lisette Hilton,University of Miami(From left) Isaac R. L. Xu; Derek J. Van Booven; and Himanshu Arora, Ph.D. Credit: University of MiamiResearchers at Sylvester Comprehensive Cancer Center an

Updated on: December 25,2023

The power of machine learning in prostate cancer imaging

by Lisette Hilton,University of Miami(From left) Isaac R. L. Xu; Derek J. Van Booven; and Himanshu Arora, Ph.D. Credit: University of MiamiResearchers at Sylvester Comprehensive Cancer Center an

Updated on:December 25,2023

A feasibility study for salvage radiation therapy in prostate cancer

by Impact Journals LLCCredit: CC0 Public DomainAn editorial paper waspublishedinOncoscienceon May 20, 2024, titled, "Deep learning-assisted lesion segmentation in PET/CT i

Updated on: July 08,2024

A feasibility study for salvage radiation therapy in prostate cancer

by Impact Journals LLCCredit: CC0 Public DomainAn editorial paper waspublishedinOncoscienceon May 20, 2024, titled, "Deep learning-assisted lesion segmentation in PET/CT i

Updated on:July 08,2024

Researchers link ovarian cancer to bacteria colonization in microbiome

by Susan Murphy,Mayo Clinicβ-diversities measures were compared. For β-diversity, Bray–Curtis (BC), unweighted, and weighted, UniFrac distance metrics were reported. The most significant metric

Updated on: February 20,2024

Researchers link ovarian cancer to bacteria colonization in microbiome

by Susan Murphy,Mayo Clinicβ-diversities measures were compared. For β-diversity, Bray–Curtis (BC), unweighted, and weighted, UniFrac distance metrics were reported. The most significant metric

Updated on:February 20,2024

CAR-T cell researchers optimistic about future of treating blood cancers

by Kelley Luckstein,Mayo ClinicCredit: AI-generated imageSurvival outcomes using chimeric antigen receptor-T cell therapy (CAR-T cell therapy) continue to be impressive for patients with some bl

Updated on: April 09,2024

CAR-T cell researchers optimistic about future of treating blood cancers

by Kelley Luckstein,Mayo ClinicCredit: AI-generated imageSurvival outcomes using chimeric antigen receptor-T cell therapy (CAR-T cell therapy) continue to be impressive for patients with some bl

Updated on:April 09,2024

Targeted therapy extends survival in cancers of unknown primary

by Julia Bird, Universitätsklinikum HeidelbergProgression-free survival in the intention-to-treat population, category 1 patients. Credit:The Lancet(2024). DOI: 10.1016/S0140-6736(24)00814

Updated on: August 27,2024

Targeted therapy extends survival in cancers of unknown primary

by Julia Bird, Universitätsklinikum HeidelbergProgression-free survival in the intention-to-treat population, category 1 patients. Credit:The Lancet(2024). DOI: 10.1016/S0140-6736(24)00814

Updated on:August 27,2024

New tool combines evolution and AI to predict prostate cancer recurrence more than a decade ahead

New tool combines evolution and AI to predict prostate cancer recurrence more than a decade aheadbyInstitute of Cancer ResearchStudy design. Credit:Nature Cancer(2024). DOI: 10.1038/

Updated on: July 17,2024

New tool combines evolution and AI to predict prostate cancer recurrence more than a decade ahead

New tool combines evolution and AI to predict prostate cancer recurrence more than a decade aheadbyInstitute of Cancer ResearchStudy design. Credit:Nature Cancer(2024). DOI: 10.1038/

Updated on:July 17,2024

New drug combinations could improve therapies for breast cancer, other aggressive cancers

by Angela Yeager,Oregon Health & Science UniversityQuantification of CD8+T cells by multispectral flow cytometry in an ex vivo co-culture assay. Credit:Cell Reports Medicine&nbsp

Updated on: September 10,2024

New drug combinations could improve therapies for breast cancer, other aggressive cancers

by Angela Yeager,Oregon Health & Science UniversityQuantification of CD8+T cells by multispectral flow cytometry in an ex vivo co-culture assay. Credit:Cell Reports Medicine&nbsp

Updated on:September 10,2024

Addition of durvalumab, bevacizumab to TACE beneficial in liver cancer

by Elana GotkineFor patients with embolization-eligible unresectable hepatocellular carcinoma (uHCC), the addition of durvalumab (D) and bevacizumab (B) to transarterial chemoembolization (TACE) impro

Updated on: March 22,2024

Addition of durvalumab, bevacizumab to TACE beneficial in liver cancer

by Elana GotkineFor patients with embolization-eligible unresectable hepatocellular carcinoma (uHCC), the addition of durvalumab (D) and bevacizumab (B) to transarterial chemoembolization (TACE) impro

Updated on:March 22,2024

Study in mice examines impact of reused cooking oil on breast cancer progression

by Sharita Forrest ,University of Illinois at Urbana-ChampaignThe compounds in frying oils that are repeatedly reheated to high temperatures may trigger cell proliferation and metastases i

Updated on: April 23,2024

Study in mice examines impact of reused cooking oil on breast cancer progression

by Sharita Forrest ,University of Illinois at Urbana-ChampaignThe compounds in frying oils that are repeatedly reheated to high temperatures may trigger cell proliferation and metastases i

Updated on:April 23,2024