Study finds calcium, vitamin D supplements may reduce cancer mortality in long term

by Elana GotkineFor postmenopausal women, calcium and vitamin D (CaD) supplements may reduce cancer mortality and increase cardiovascular disease (CVD) mortality after more than 20 years of follow-up,

Updated on: March 20,2024

Study finds calcium, vitamin D supplements may reduce cancer mortality in long term

by Elana GotkineFor postmenopausal women, calcium and vitamin D (CaD) supplements may reduce cancer mortality and increase cardiovascular disease (CVD) mortality after more than 20 years of follow-up,

Updated on:March 20,2024

Supercharging CAR-T cells for cancer treatment

byEcole Polytechnique Federale de LausanneIL-10-expressing CAR T cells counter dysfunction in tumors.a, Schematic depicting the HER2 CAR and IL-10 HER2 CAR constructs; scFv, single-chain v

Updated on: January 26,2024

Supercharging CAR-T cells for cancer treatment

byEcole Polytechnique Federale de LausanneIL-10-expressing CAR T cells counter dysfunction in tumors.a, Schematic depicting the HER2 CAR and IL-10 HER2 CAR constructs; scFv, single-chain v

Updated on:January 26,2024

CAR-T Therapy Under Scrutiny: The Emerging Risk of Secondary Malignant Tumors

CAR-T therapy has long been an effective treatment for hematological cancers such as leukemia and lymphoma. However, some patients have developed secondary malignant tumors after undergoing CAR-T ......

Updated on: May 29,2024

CAR-T Therapy Under Scrutiny: The Emerging Risk of Secondary Malignant Tumors

CAR-T therapy has long been an effective treatment for hematological cancers such as leukemia and lymphoma. However, some patients have developed secondary malignant tumors after undergoing CAR-T ......

Updated on:May 29,2024

Blood test identifies acute myeloid leukemia patients at greater risk for relapse after bone marrow transplant

byNIH/National Heart, Lung and Blood InstituteDetection and Impact of Residual Variants on Clinical Outcomes by Gene A, Heatmap illustrating for each patient (n = 1075) their cohort assignment,

Updated on: January 15,2024

Blood test identifies acute myeloid leukemia patients at greater risk for relapse after bone marrow transplant

byNIH/National Heart, Lung and Blood InstituteDetection and Impact of Residual Variants on Clinical Outcomes by Gene A, Heatmap illustrating for each patient (n = 1075) their cohort assignment,

Updated on:January 15,2024

Estrogen-negative cancers respond to anti-estrogenic therapies, study shows

byHokkaido UniversityCredit: Nabeel KajiharaAnti-estrogenic therapies can suppress the growth of cancer that does not express estrogen receptors; when combined with immune checkpoint inhibitor t

Updated on: January 22,2024

Estrogen-negative cancers respond to anti-estrogenic therapies, study shows

byHokkaido UniversityCredit: Nabeel KajiharaAnti-estrogenic therapies can suppress the growth of cancer that does not express estrogen receptors; when combined with immune checkpoint inhibitor t

Updated on:January 22,2024

Exploring mini-labs as an alternative to animal testing for evaluating radiopharmaceuticals

byHelmholtz Association of German Research CentresMPS layout; red—media circuit with integrated pump; blue—pneumatic connectors; yellow—microwells for organoids; green—LUER-connectors). Credit:&

Updated on: January 07,2024

Exploring mini-labs as an alternative to animal testing for evaluating radiopharmaceuticals

byHelmholtz Association of German Research CentresMPS layout; red—media circuit with integrated pump; blue—pneumatic connectors; yellow—microwells for organoids; green—LUER-connectors). Credit:&

Updated on:January 07,2024

Existing cancer drug ponatinib could be repurposed to fight certain aggressive cancers

byNanyang Technological UniversitySchematic summary of mechanisms of action of ponatinib in ALT cells. Ponatinib disrupts alternative lengthening of telomeres mechanisms by inducing telomeric C-

Updated on: January 10,2024

Existing cancer drug ponatinib could be repurposed to fight certain aggressive cancers

byNanyang Technological UniversitySchematic summary of mechanisms of action of ponatinib in ALT cells. Ponatinib disrupts alternative lengthening of telomeres mechanisms by inducing telomeric C-

Updated on:January 10,2024

Training the immune system to prevent cancer—researchers discover paradigm-shifting approach

by Courtney Perrett,University of MissouriSA-4-1BBL treatment protected mice from developing lung tumors induced by NNK.AExperimental design, and treatment timeline.Female A/J

Updated on: January 26,2024

Training the immune system to prevent cancer—researchers discover paradigm-shifting approach

by Courtney Perrett,University of MissouriSA-4-1BBL treatment protected mice from developing lung tumors induced by NNK.AExperimental design, and treatment timeline.Female A/J

Updated on:January 26,2024

Uptake of HIV prevention medication doubles with mix of digital health interventions, study finds

by University of California, Los AngelesCredit: Pixabay/CC0 Public DomainA UCLA Health-led study found a combination of interventions of one-on-one telehealth coaching, peer support forums, and a

Updated on: May 16,2024

Uptake of HIV prevention medication doubles with mix of digital health interventions, study finds

by University of California, Los AngelesCredit: Pixabay/CC0 Public DomainA UCLA Health-led study found a combination of interventions of one-on-one telehealth coaching, peer support forums, and a

Updated on:May 16,2024

A new therapeutic target turns the immune system against lymphoma

by Ecole Polytechnique Federale de LausanneCredit: CC0 Public DomainNon-Hodgkin's lymphoma (NHL) is a group of cancers that originate in the lymph nodes and affect white blood cells of the im

Updated on: March 25,2024

A new therapeutic target turns the immune system against lymphoma

by Ecole Polytechnique Federale de LausanneCredit: CC0 Public DomainNon-Hodgkin's lymphoma (NHL) is a group of cancers that originate in the lymph nodes and affect white blood cells of the im

Updated on:March 25,2024

All in the blood: New way to detect drug resistance in ovarian cancer patients

byWalter and Eliza Hall InstituteThe "splicing" mechanism in cancer cells allows them to repair their DNA and avoid the cell death caused by PARP inhibitor therapy, resulting in drug r

Updated on: December 02,2024

All in the blood: New way to detect drug resistance in ovarian cancer patients

byWalter and Eliza Hall InstituteThe "splicing" mechanism in cancer cells allows them to repair their DNA and avoid the cell death caused by PARP inhibitor therapy, resulting in drug r

Updated on:December 02,2024

Innovative test that detects complex DNA patterns may improve mesothelioma detection rate in blood

by Susan Murphy,Mayo ClinicStudy design. Our study involved detecting junctions that result from chromosomal rearrangements, insertions and deletions in mesothelioma in Step 1, then designing pr

Updated on: December 02,2024

Innovative test that detects complex DNA patterns may improve mesothelioma detection rate in blood

by Susan Murphy,Mayo ClinicStudy design. Our study involved detecting junctions that result from chromosomal rearrangements, insertions and deletions in mesothelioma in Step 1, then designing pr

Updated on:December 02,2024