Faster genomics-based diagnosis may accelerate targeted treatment of patients with myeloid neoplasms

byElsevierA: Comparison of clinical assay variant allele fraction (VAF) and Ion Torrent Genexus VAF showed high correlation (r2= 0.98) across a broad range of VAFs, including both in-house

Updated on: December 22,2023

Faster genomics-based diagnosis may accelerate targeted treatment of patients with myeloid neoplasms

byElsevierA: Comparison of clinical assay variant allele fraction (VAF) and Ion Torrent Genexus VAF showed high correlation (r2= 0.98) across a broad range of VAFs, including both in-house

Updated on:December 22,2023

Differences in animal biology can affect cancer drug development

byWeill Cornell Medical CollegeDifferential co-occurrence and effects of KRAS, TP53 and LKB1 mutations on human and mouse LUADs (A) MSK Impact oncoprint of co-occurrence of KRAS, TP53 and LKB1 m

Updated on: December 20,2023

Differences in animal biology can affect cancer drug development

byWeill Cornell Medical CollegeDifferential co-occurrence and effects of KRAS, TP53 and LKB1 mutations on human and mouse LUADs (A) MSK Impact oncoprint of co-occurrence of KRAS, TP53 and LKB1 m

Updated on:December 20,2023

Curbing blood cancers by teaching immune cells to kill mutant stem cells

by Nancy Fliesler,Children's Hospital BostonROS and TLR3 signaling mediates the "eat-me" and "don't eat me" signals that determine stem cell clonal selection by macro

Updated on: October 24,2024

Curbing blood cancers by teaching immune cells to kill mutant stem cells

by Nancy Fliesler,Children's Hospital BostonROS and TLR3 signaling mediates the "eat-me" and "don't eat me" signals that determine stem cell clonal selection by macro

Updated on:October 24,2024

Researchers find the key to genome-modifying drugs' sensitivity in malignant blood diseases

by Josep Carreras Leukaemia Research InstituteImpact of azacitidine on global DNA methylation patterns and definition of EPIAZA signature in patients with MDS. (A) Study design and workflow. (B,

Updated on: March 20,2024

Researchers find the key to genome-modifying drugs' sensitivity in malignant blood diseases

by Josep Carreras Leukaemia Research InstituteImpact of azacitidine on global DNA methylation patterns and definition of EPIAZA signature in patients with MDS. (A) Study design and workflow. (B,

Updated on:March 20,2024

Estrogen may facilitate the growth of liver metastases in non-sex-specific cancers

byMcGill UniversityCancer cell during cell division. Credit: National Institutes of HealthIt is known that the tumor microenvironment plays an important role in the progression of cancer. But co

Updated on: December 22,2023

Estrogen may facilitate the growth of liver metastases in non-sex-specific cancers

byMcGill UniversityCancer cell during cell division. Credit: National Institutes of HealthIt is known that the tumor microenvironment plays an important role in the progression of cancer. But co

Updated on:December 22,2023

Combination of chemo and diabetes drugs shows potential for treating Ewing sarcoma

byHouston MethodistStephen T. Wong, Ph.D., Associate Director, Cores, Biostatistics and BioinformaticsHouston Methodist Cancer Center. Credit: Houston MethodistEwing sarcoma, an aggressive tumor

Updated on: December 22,2023

Combination of chemo and diabetes drugs shows potential for treating Ewing sarcoma

byHouston MethodistStephen T. Wong, Ph.D., Associate Director, Cores, Biostatistics and BioinformaticsHouston Methodist Cancer Center. Credit: Houston MethodistEwing sarcoma, an aggressive tumor

Updated on:December 22,2023

When cells cycle fast, cancer gets a jumpstart

byYale UniversityCredit: CC0 Public DomainThe progression of cancer has been studied extensively, and the key steps in this journey have been well mapped, at least in some solid tumors: Lesions

Updated on: December 22,2023

When cells cycle fast, cancer gets a jumpstart

byYale UniversityCredit: CC0 Public DomainThe progression of cancer has been studied extensively, and the key steps in this journey have been well mapped, at least in some solid tumors: Lesions

Updated on:December 22,2023

Conversation tool to help cancer patients with treatment choices

byLeiden UniversityCredit: Pixabay/CC0 Public DomainResearchers at the Leiden Institute of Advanced Computer Science (LIACS) are collaborating on the development of a conversation tool for patie

Updated on: December 21,2023

Conversation tool to help cancer patients with treatment choices

byLeiden UniversityCredit: Pixabay/CC0 Public DomainResearchers at the Leiden Institute of Advanced Computer Science (LIACS) are collaborating on the development of a conversation tool for patie

Updated on:December 21,2023

Two common types of antidepressants found to be safe for most stroke survivors

by American Heart AssociationCredit: Unsplash/CC0 Public DomainMost stroke survivors were able to safely take two types of common antidepressants, according to a preliminary study to be presented

Updated on: May 06,2024

Two common types of antidepressants found to be safe for most stroke survivors

by American Heart AssociationCredit: Unsplash/CC0 Public DomainMost stroke survivors were able to safely take two types of common antidepressants, according to a preliminary study to be presented

Updated on:May 06,2024

The Sweet Dilemma: Fructose's Impact on Cancer and Immunity

Updated on: July 13,2024

The Sweet Dilemma: Fructose's Impact on Cancer and Immunity

Updated on:July 13,2024

Why breast cancer survivors don't take their medication, and what can be done about it

by Lisa Marshall,University of Colorado at BoulderCredit: Unsplash/CC0 Public DomainFor roughly 80% of breast cancer survivors, treatment doesn't end with surgery, radiation and chemotherapy

Updated on: January 08,2024

Why breast cancer survivors don't take their medication, and what can be done about it

by Lisa Marshall,University of Colorado at BoulderCredit: Unsplash/CC0 Public DomainFor roughly 80% of breast cancer survivors, treatment doesn't end with surgery, radiation and chemotherapy

Updated on:January 08,2024

Low income linked to high recurrence risk, poorer survival in women with ER-positive breast cancer

by Roswell Park Comprehensive Cancer CenterCredit: Unsplash/CC0 Public DomainPatients with early-stage estrogen receptor-positive breast cancer who live in low-income neighborhoods are likelier to hav

Updated on: December 20,2023

Low income linked to high recurrence risk, poorer survival in women with ER-positive breast cancer

by Roswell Park Comprehensive Cancer CenterCredit: Unsplash/CC0 Public DomainPatients with early-stage estrogen receptor-positive breast cancer who live in low-income neighborhoods are likelier to hav

Updated on:December 20,2023