Scientists identify potential drug target for BRCA-mutated tumours

byInstitute of Cancer ResearchCrystal structure of EXD2 exonuclease domain in spacefill format. Credit: Image generated fromPDBA new study has uncovered a previously unknown role for the e

Updated on: December 22,2023

Scientists identify potential drug target for BRCA-mutated tumours

byInstitute of Cancer ResearchCrystal structure of EXD2 exonuclease domain in spacefill format. Credit: Image generated fromPDBA new study has uncovered a previously unknown role for the e

Updated on:December 22,2023

Prozac fights deadly childhood brain cancer

by Hayley Jarvis,Brunel UniversityKiller T cells surround a cancer cell. Credit: NIHThe anti-depressant drug Prozac could be used to tackle one of the deadliest childhood tumours and possibly ot

Updated on: December 22,2023

Prozac fights deadly childhood brain cancer

by Hayley Jarvis,Brunel UniversityKiller T cells surround a cancer cell. Credit: NIHThe anti-depressant drug Prozac could be used to tackle one of the deadliest childhood tumours and possibly ot

Updated on:December 22,2023

How cancer cells die: Scientists explore new pathways of pyroptosis, killer kin of apoptosis

by Delthia Ricks , Medical XpressLymphoid BLaER1 cells undergo PANX1-dominant lysis. (A to C) BLaER1 cells were treated with topoisomerase poisons doxorubicin (2 μM) or etoposide (50 μM) for 24 hours.

Updated on: December 18,2023

How cancer cells die: Scientists explore new pathways of pyroptosis, killer kin of apoptosis

by Delthia Ricks , Medical XpressLymphoid BLaER1 cells undergo PANX1-dominant lysis. (A to C) BLaER1 cells were treated with topoisomerase poisons doxorubicin (2 μM) or etoposide (50 μM) for 24 hours.

Updated on:December 18,2023

Drugs for treating breast cancer in women are effective and well tolerated in men

byEuropean Society for Medical OncologyThere is growing evidence that drugs approved for the treatment of breast cancer in women are also effective and well tolerated in men, according to the la

Updated on: December 18,2023

Drugs for treating breast cancer in women are effective and well tolerated in men

byEuropean Society for Medical OncologyThere is growing evidence that drugs approved for the treatment of breast cancer in women are also effective and well tolerated in men, according to the la

Updated on:December 18,2023

Treatment of aggressive breast cancer improved by immunotherapy-chemotherapy combination

byUniversity of Pittsburgh Schools of the Health SciencesLeisha Emens, M.D., Ph.D., co-leader of the UPMC Hillman Cancer Immunology and Immunotherapy Program. Credit: UPMCPatients with an aggres

Updated on: December 18,2023

Treatment of aggressive breast cancer improved by immunotherapy-chemotherapy combination

byUniversity of Pittsburgh Schools of the Health SciencesLeisha Emens, M.D., Ph.D., co-leader of the UPMC Hillman Cancer Immunology and Immunotherapy Program. Credit: UPMCPatients with an aggres

Updated on:December 18,2023

Five facts you may not know about brain tumors

by Laura Hegwer,Rush University Medical CenterCredit: Unsplash/CC0 Public DomainBrain tumors scare most people, but there are still reasons to be hopeful if you learn you have an abnormal growth

Updated on: December 23,2023

Five facts you may not know about brain tumors

by Laura Hegwer,Rush University Medical CenterCredit: Unsplash/CC0 Public DomainBrain tumors scare most people, but there are still reasons to be hopeful if you learn you have an abnormal growth

Updated on:December 23,2023

The Human Tumor Atlas Network: Mapping Cancer's Complexity and Evolution

The Human Tumor Atlas Network (HTAN) stands at the forefront of cancer research, representing a groundbreaking initiative funded by the National Cancer Institute (NCI) as part of the ambitious Cancer Moonshot℠ program. Launched in 2018, HTAN's primary mis

Updated on: November 07,2024

The Human Tumor Atlas Network: Mapping Cancer's Complexity and Evolution

The Human Tumor Atlas Network (HTAN) stands at the forefront of cancer research, representing a groundbreaking initiative funded by the National Cancer Institute (NCI) as part of the ambitious Cancer Moonshot℠ program. Launched in 2018, HTAN's primary mis

Updated on:November 07,2024

Researchers test previously approved FDA drugs to treat Lowe syndrome

by Purdue UniversityR. Claudio Aguilar, a Purdue University researcher, has developed a patented therapeutic strategy for Lowe syndrome by repurposing two drugs previously approved by the U.S. Fo

Updated on: May 26,2024

Researchers test previously approved FDA drugs to treat Lowe syndrome

by Purdue UniversityR. Claudio Aguilar, a Purdue University researcher, has developed a patented therapeutic strategy for Lowe syndrome by repurposing two drugs previously approved by the U.S. Fo

Updated on:May 26,2024

How two 1990s discoveries have led to (some) cured cancers, and a Nobel Prize

by Craig Gedye,The ConversationCredit: CC0 Public DomainThis year's award of theNobel Prize for Physiology and Medicineto James P. Allison and Tasuku Honjo, for their work in the

Updated on: March 14,2024

How two 1990s discoveries have led to (some) cured cancers, and a Nobel Prize

by Craig Gedye,The ConversationCredit: CC0 Public DomainThis year's award of theNobel Prize for Physiology and Medicineto James P. Allison and Tasuku Honjo, for their work in the

Updated on:March 14,2024

Stage and receptor status can indicate a breast cancer survivor's risk of recurrence

Updated on: December 22,2023

Stage and receptor status can indicate a breast cancer survivor's risk of recurrence

Updated on:December 22,2023

Routine HPV testing may be warranted for sinonasal cancers

(HealthDay)—Only one in four patients with sinonasal squamous cell carcinoma (SNSCC) is tested for human papillomavirus (HPV), according to a study published online Dec. 30 inCancer.Jamie R. Oli

Updated on: December 20,2023

Routine HPV testing may be warranted for sinonasal cancers

(HealthDay)—Only one in four patients with sinonasal squamous cell carcinoma (SNSCC) is tested for human papillomavirus (HPV), according to a study published online Dec. 30 inCancer.Jamie R. Oli

Updated on:December 20,2023

Response to neoadjuvant chemo for breast cancer varies by sex

Both proportions and odds of pathologic complete response (pCR) to neoadjuvant chemotherapy (NAC) are numerically lower in men with breast cancer (BC) versus women with BC for each tumor subtype, acco

Updated on: December 20,2023

Response to neoadjuvant chemo for breast cancer varies by sex

Both proportions and odds of pathologic complete response (pCR) to neoadjuvant chemotherapy (NAC) are numerically lower in men with breast cancer (BC) versus women with BC for each tumor subtype, acco

Updated on:December 20,2023