Blood-based biomarker may redefine future treatment for advanced melanoma

byElsevierCirculating tumor DNA (ctDNA) correlates with radiology disease assessment and patient outcome. For patient A, biomarkers in their blood decreased over time and the radiology showed th

Updated on: January 05,2024 13

Blood-based biomarker may redefine future treatment for advanced melanoma

byElsevierCirculating tumor DNA (ctDNA) correlates with radiology disease assessment and patient outcome. For patient A, biomarkers in their blood decreased over time and the radiology showed th

Updated on:January 05,2024 13

Establishment of breast phyllodes tumor cell lines to facilitate future studies

by Compuscript LtdCredit: CC0 Public DomainBreast phyllodes tumors (PTs) are biphasic, with epithelial and stromal components. Although the PT incidence is low (approximately 1% of all breast tumors),

Updated on: December 26,2023 9

Establishment of breast phyllodes tumor cell lines to facilitate future studies

by Compuscript LtdCredit: CC0 Public DomainBreast phyllodes tumors (PTs) are biphasic, with epithelial and stromal components. Although the PT incidence is low (approximately 1% of all breast tumors),

Updated on:December 26,2023 9

Disorderly DNA helps cancer cells evade treatment

byNorthwestern UniversityWhen the chromatin packing is heterogenous and disordered, a cell demonstrates more plasticity. Credit: Northwestern UniversityEach cell in the human body holds a full t

Updated on: December 22,2023 10

Disorderly DNA helps cancer cells evade treatment

byNorthwestern UniversityWhen the chromatin packing is heterogenous and disordered, a cell demonstrates more plasticity. Credit: Northwestern UniversityEach cell in the human body holds a full t

Updated on:December 22,2023 10

Team of sister scientists identify a possible genetic culprit for uterine corpus endometrial cancer

by Allison Trouten,Medical University of South CarolinaMYO5B mRNA is elevated in uterine corpus endometrial carcinoma (UCEC) patients. A. The expression of MYO5B in various control tissues and t

Updated on: December 26,2023 10

Team of sister scientists identify a possible genetic culprit for uterine corpus endometrial cancer

by Allison Trouten,Medical University of South CarolinaMYO5B mRNA is elevated in uterine corpus endometrial carcinoma (UCEC) patients. A. The expression of MYO5B in various control tissues and t

Updated on:December 26,2023 10

Timely surveillance with chest imaging may benefit colorectal cancer patients

byAmerican College of SurgeonsEarly chest imaging may benefit colorectal cancer patients. Credit: American College of SurgeonsColorectal cancer patients with certain clinical characteristics may

Updated on: December 25,2023 10

Timely surveillance with chest imaging may benefit colorectal cancer patients

byAmerican College of SurgeonsEarly chest imaging may benefit colorectal cancer patients. Credit: American College of SurgeonsColorectal cancer patients with certain clinical characteristics may

Updated on:December 25,2023 10

Racial disparity in pro-metastatic tumor microenvironment among women with residual breast cancer after NAC

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainResidual tumors from Black patients with estrogen receptor (ER)-positive/HER2-negative primary breast cancer treated w

Updated on: December 17,2023 10

Racial disparity in pro-metastatic tumor microenvironment among women with residual breast cancer after NAC

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainResidual tumors from Black patients with estrogen receptor (ER)-positive/HER2-negative primary breast cancer treated w

Updated on:December 17,2023 10

Adjuvant nivolumab + ipilimumab lacks efficacy for localized renal cell carcinoma

Disease-free survival (DFS) does not differ with adjuvant nivolumab plus ipilimumab (NIVO+IPI) compared with placebo in patients with localized renal cell carcinoma (RCC) at high risk for postnephrect

Updated on: December 22,2023 10

Adjuvant nivolumab + ipilimumab lacks efficacy for localized renal cell carcinoma

Disease-free survival (DFS) does not differ with adjuvant nivolumab plus ipilimumab (NIVO+IPI) compared with placebo in patients with localized renal cell carcinoma (RCC) at high risk for postnephrect

Updated on:December 22,2023 10

Aspirin could increase survival in cancer

byThe Royal SocietyCredit: Unsplash/CC0 Public DomainDoes aspirin increase survival in cancer patients? UK researchers say that despite the smaller side-effects of aspirin, taking the drug has a

Updated on: December 18,2023 10

Aspirin could increase survival in cancer

byThe Royal SocietyCredit: Unsplash/CC0 Public DomainDoes aspirin increase survival in cancer patients? UK researchers say that despite the smaller side-effects of aspirin, taking the drug has a

Updated on:December 18,2023 10

Normalizing tumor blood vessels may improve immunotherapy against brain cancer

by Noah Brown,Massachusetts General HospitalAnti-VEGF treatment improves the efficacy of EGFRvIII-CAR-T cells in murine GBM tumor models. (A) Schematic representation of experimental setup to ev

Updated on: January 04,2024 9

Normalizing tumor blood vessels may improve immunotherapy against brain cancer

by Noah Brown,Massachusetts General HospitalAnti-VEGF treatment improves the efficacy of EGFRvIII-CAR-T cells in murine GBM tumor models. (A) Schematic representation of experimental setup to ev

Updated on:January 04,2024 9

Financial impacts of cancer found to intensify disease burden among German patients

byEuropean Society for Medical OncologyA study conducted in Germany draws attention to the fact that the socio-economic burden of cancer is real in Europe too, and not only in the context of the

Updated on: December 18,2023 15

Financial impacts of cancer found to intensify disease burden among German patients

byEuropean Society for Medical OncologyA study conducted in Germany draws attention to the fact that the socio-economic burden of cancer is real in Europe too, and not only in the context of the

Updated on:December 18,2023 15

Actin cytoskeleton remodeling protects tumor cells against immune attack

by Luxembourg Institute of HealthConfocal microscopy image. Accumulation of actin filaments (in green) at the immunological synapse of a resistant cancer cell in contact with an NK cell (in red). Cell

Updated on: December 18,2023 10

Actin cytoskeleton remodeling protects tumor cells against immune attack

by Luxembourg Institute of HealthConfocal microscopy image. Accumulation of actin filaments (in green) at the immunological synapse of a resistant cancer cell in contact with an NK cell (in red). Cell

Updated on:December 18,2023 10

Cancer stem cells use 'normal' genes in abnormal ways

by Garth Sundem,CU Anschutz Medical CampusMayumi Fajita, MD, PhD and colleagues show that CDK1 interacts with Sox2 to keep cancer stem cells 'stemmy'. Credit: University of Colorado Canc

Updated on: December 18,2023 19

Cancer stem cells use 'normal' genes in abnormal ways

by Garth Sundem,CU Anschutz Medical CampusMayumi Fajita, MD, PhD and colleagues show that CDK1 interacts with Sox2 to keep cancer stem cells 'stemmy'. Credit: University of Colorado Canc

Updated on:December 18,2023 19