New therapeutic strategy for chemotherapy resistance in ovarian cancer

byThe Wistar InstituteDr. Rugang Zhang. Credit: The Wistar InstituteA study from The Wistar Institute demonstrated that NAMPT, an enzyme critical for NAD+ biosynthesis, mediates selection of ste

Updated on: December 22,2023

New therapeutic strategy for chemotherapy resistance in ovarian cancer

byThe Wistar InstituteDr. Rugang Zhang. Credit: The Wistar InstituteA study from The Wistar Institute demonstrated that NAMPT, an enzyme critical for NAD+ biosynthesis, mediates selection of ste

Updated on:December 22,2023

Scientists discover metabolic feature that allows melanoma cells to spread

by Katie Regan,UT Southwestern Medical CenterResearchers involved in the study include (from left) Drs. Brandon Faubert, Alpaslan Tasdogan, Sean Morrison, and Ralph DeBerardinis. Credit: UTSWRes

Updated on: December 23,2023

Scientists discover metabolic feature that allows melanoma cells to spread

by Katie Regan,UT Southwestern Medical CenterResearchers involved in the study include (from left) Drs. Brandon Faubert, Alpaslan Tasdogan, Sean Morrison, and Ralph DeBerardinis. Credit: UTSWRes

Updated on:December 23,2023

A blood sample 24 hours after the start of chemotherapy can predict survival

byUniversity of BergenMass cytometry analysis of early response evaluation by single-cell signaling to profile.aPeripheral blood samples were collected from 32 AML patients treated w

Updated on: December 25,2023

A blood sample 24 hours after the start of chemotherapy can predict survival

byUniversity of BergenMass cytometry analysis of early response evaluation by single-cell signaling to profile.aPeripheral blood samples were collected from 32 AML patients treated w

Updated on:December 25,2023

Revealing one of the mechanisms by which thyroid cancer becomes resistant to lenvatinib-a

by Shinshu UniversityThe EGFR-mediated pathway, which is not targeted by lenvatinib, is activated for survival in thyroid cancer cells under the potent inhibition of the VEGFR and FGFR families by len

Updated on: December 26,2023

Revealing one of the mechanisms by which thyroid cancer becomes resistant to lenvatinib-a

by Shinshu UniversityThe EGFR-mediated pathway, which is not targeted by lenvatinib, is activated for survival in thyroid cancer cells under the potent inhibition of the VEGFR and FGFR families by len

Updated on:December 26,2023

Exploring reasons for higher breast cancer risk among Caribbean women

by Sylvester Comprehensive Cancer CenterSylvester researcher Sophia George, Ph.D., who was raised in the Caribbean country of Dominica. Credit: Sylvester Comprehensive Cancer CenterA new study from re

Updated on: November 11,2024

Exploring reasons for higher breast cancer risk among Caribbean women

by Sylvester Comprehensive Cancer CenterSylvester researcher Sophia George, Ph.D., who was raised in the Caribbean country of Dominica. Credit: Sylvester Comprehensive Cancer CenterA new study from re

Updated on:November 11,2024

Study maps alterations that make melanoma more severe, could lead to better therapies and diagnosis

by André Julião,FAPESPStudy design, resources and methodology. A major aim (steps 1–2) is the discovery and validation of genome-wide methylation alterations associated with the UV mutational si

Updated on: February 20,2024

Study maps alterations that make melanoma more severe, could lead to better therapies and diagnosis

by André Julião,FAPESPStudy design, resources and methodology. A major aim (steps 1–2) is the discovery and validation of genome-wide methylation alterations associated with the UV mutational si

Updated on:February 20,2024

Gene loss enhances metastasis and cancer progression

by Melissa Rohman,Northwestern UniversityAn in vivo genome-wide CRISPR-Cas9 KO screen identifying CTC-promoting genetic factors. (A) Experimental design of the genome-wide CRISPR-Cas9 KO screen

Updated on: December 25,2023

Gene loss enhances metastasis and cancer progression

by Melissa Rohman,Northwestern UniversityAn in vivo genome-wide CRISPR-Cas9 KO screen identifying CTC-promoting genetic factors. (A) Experimental design of the genome-wide CRISPR-Cas9 KO screen

Updated on:December 25,2023

Method that uses combination of immune cells could provide clearer prognoses

by Elin Bäckström,Swedish Research CouncilPrognostic value of CD8+T cells and CD68+CD163+macrophages revealed by comprehensive characterization of immune cell subsets in 286 therapy-

Updated on: January 04,2024

Method that uses combination of immune cells could provide clearer prognoses

by Elin Bäckström,Swedish Research CouncilPrognostic value of CD8+T cells and CD68+CD163+macrophages revealed by comprehensive characterization of immune cell subsets in 286 therapy-

Updated on:January 04,2024

Top medical groups, hospitals urge better access to lung cancer screening

by Cara MurezScreening tests routinely catch cases of breast and colon cancer early, but a screening test for lung cancer is sorely underused in high-risk people and that needs to change, more than 50

Updated on: December 20,2023

Top medical groups, hospitals urge better access to lung cancer screening

by Cara MurezScreening tests routinely catch cases of breast and colon cancer early, but a screening test for lung cancer is sorely underused in high-risk people and that needs to change, more than 50

Updated on:December 20,2023

Preclinical study finds novel bone cancer therapy has 99% success rate

byAston UniversityProfessor Richard Martin. Credit: Aston UniversityBioactive glasses, a filling material which can bond to tissue and improve the strength of bones and teeth, has been combined

Updated on: September 27,2024

Preclinical study finds novel bone cancer therapy has 99% success rate

byAston UniversityProfessor Richard Martin. Credit: Aston UniversityBioactive glasses, a filling material which can bond to tissue and improve the strength of bones and teeth, has been combined

Updated on:September 27,2024

Boosting immunotherapy in non-responsive cancer cells

by Surabhi Chandra,Indian Institute of ScienceAvik Chattopadhyay working in the lab. Credit: Nikita RamtekeCancer immunotherapy primes a patient's immune system to better find and destroy ca

Updated on: January 26,2024

Boosting immunotherapy in non-responsive cancer cells

by Surabhi Chandra,Indian Institute of ScienceAvik Chattopadhyay working in the lab. Credit: Nikita RamtekeCancer immunotherapy primes a patient's immune system to better find and destroy ca

Updated on:January 26,2024

Peripheral blood haplo-SCT feasible for leukemia patients 70 years and older

by Elana GotkineFor patients with acute myeloid leukemia (AML)/myelodysplastic syndromes (MDS) aged 70 years and older, haploidentical stem cell transplantation (Haplo-SCT) using a nonmyeloablative co

Updated on: December 28,2023

Peripheral blood haplo-SCT feasible for leukemia patients 70 years and older

by Elana GotkineFor patients with acute myeloid leukemia (AML)/myelodysplastic syndromes (MDS) aged 70 years and older, haploidentical stem cell transplantation (Haplo-SCT) using a nonmyeloablative co

Updated on:December 28,2023