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MSC-mediated mitochondrial transfer holds therapeutic promise for Leber's hereditary optic neuropathy patients

MSC-mediated mitochondrial transfer holds therapeutic promise for Leber's hereditary optic neuropathy patients

byScience China PressPatch-clamp recordings demonstrated that LHON neurons, which typically exhibit impaired sodium and potassium currents, showed restored electrophysiological function after co

MSC-mediated mitochondrial transfer holds therapeutic promise for Leber's hereditary optic neuropathy patients

byScience China PressPatch-clamp recordings demonstrated that LHON neurons, which typically exhibit impaired sodium and potassium currents, showed restored electrophysiological function after co
Findings suggest common salt activates anti-tumor cells

Findings suggest common salt activates anti-tumor cells

by Friederike Gawlik, Leibniz Institute for Natural Product Research and Infection BiologyImmune cells (purple and blue) attack tumor cells (red). Highly active CD8⁺ T cells treated with sodium chlori

Findings suggest common salt activates anti-tumor cells

by Friederike Gawlik, Leibniz Institute for Natural Product Research and Infection BiologyImmune cells (purple and blue) attack tumor cells (red). Highly active CD8⁺ T cells treated with sodium chlori
High-resolution brain tumor mapping reveals possible reason why some patients don't respond to new drug

High-resolution brain tumor mapping reveals possible reason why some patients don't respond to new drug

byWeizmann Institute of ScienceGraphical abstract. Credit:Cell(2024). DOI: 10.1016/j.cell.2024.03.029The cells that make up cancerous brain tumors are extremely varied and sometimes

High-resolution brain tumor mapping reveals possible reason why some patients don't respond to new drug

byWeizmann Institute of ScienceGraphical abstract. Credit:Cell(2024). DOI: 10.1016/j.cell.2024.03.029The cells that make up cancerous brain tumors are extremely varied and sometimes
New anti-cancer 'degrader' targets protein essential to infant leukemia

New anti-cancer 'degrader' targets protein essential to infant leukemia

byVan Andel Research InstituteDiscovery of a first-in-class, highly potent VHL-recruiting ENL PROTAC degrader, MS41. Credit:Science Advances(2024). DOI: 10.1126/sciadv.ado1432Scienti

New anti-cancer 'degrader' targets protein essential to infant leukemia

byVan Andel Research InstituteDiscovery of a first-in-class, highly potent VHL-recruiting ENL PROTAC degrader, MS41. Credit:Science Advances(2024). DOI: 10.1126/sciadv.ado1432Scienti
Potential new drug could target rare childhood brain tumor

Potential new drug could target rare childhood brain tumor

Potential new drug could target rare childhood brain tumorA type of glioma. Credit: David Ellison, St. Jude Children’s Research HospitalRibociclib—a drug already used to treat breast cancer—may help s

Potential new drug could target rare childhood brain tumor

Potential new drug could target rare childhood brain tumorA type of glioma. Credit: David Ellison, St. Jude Children’s Research HospitalRibociclib—a drug already used to treat breast cancer—may help s
AI spots cancer and viral infections with nanoscale precision

AI spots cancer and viral infections with nanoscale precision

byCenter for Genomic RegulationThe image uses two colors to show specific nuclear components which allow researchers to see detailed structures within the cell nucleus at nanoscale resolution. C

AI spots cancer and viral infections with nanoscale precision

byCenter for Genomic RegulationThe image uses two colors to show specific nuclear components which allow researchers to see detailed structures within the cell nucleus at nanoscale resolution. C
Innovations in cancer treatment through targeted bacterial vaccines

Innovations in cancer treatment through targeted bacterial vaccines

byScience China PressThe schematic illustrates how the nanovaccine induces robust anti-F. nucleatum immune responses that significantly improve the efficiency of chemotherapy and reduce cancer m

Innovations in cancer treatment through targeted bacterial vaccines

byScience China PressThe schematic illustrates how the nanovaccine induces robust anti-F. nucleatum immune responses that significantly improve the efficiency of chemotherapy and reduce cancer m
Exploring key regulators of programmed cell death in melanoma and the immune system's response

Exploring key regulators of programmed cell death in melanoma and the immune system's response

byBrigham and Women’s HospitalExpression of type I interferon receptors by melanoma cells. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-51496-2A new paperpublish

Exploring key regulators of programmed cell death in melanoma and the immune system's response

byBrigham and Women’s HospitalExpression of type I interferon receptors by melanoma cells. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-51496-2A new paperpublish
New prognostic biomarker identified in small cell lung cancer

New prognostic biomarker identified in small cell lung cancer

byChinese Academy of SciencesGraphical abstract. Credit:iScience(2024). DOI: 10.1016/j.isci.2024.110413Small cell lung cancer (SCLC) is a fast-growing and highly malignant subtype of

New prognostic biomarker identified in small cell lung cancer

byChinese Academy of SciencesGraphical abstract. Credit:iScience(2024). DOI: 10.1016/j.isci.2024.110413Small cell lung cancer (SCLC) is a fast-growing and highly malignant subtype of
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