99

Breakthroughs
Sub Categories on Breakthroughs
Latest Articles
Study confirms how RNA chemical modifications benefit HIV-1

Study confirms how RNA chemical modifications benefit HIV-1

by Emily Caldwell,The Ohio State UniversityHIV-1 Virus. Credit: J Roberto Trujillo/WikipediaA chemical modification in the HIV-1 RNA genome whose function has been a matter of scientific debate

Study confirms how RNA chemical modifications benefit HIV-1

by Emily Caldwell,The Ohio State UniversityHIV-1 Virus. Credit: J Roberto Trujillo/WikipediaA chemical modification in the HIV-1 RNA genome whose function has been a matter of scientific debate
Study finds antibiotics combat gut bacteria that contribute to the pathogenesis of COVID-19

Study finds antibiotics combat gut bacteria that contribute to the pathogenesis of COVID-19

byWileyChest images of completely vaccinated sick moderate patients with SARS-CoV-2. Panel A-D: Four cases of vaccinated patients with pneumonia, no previous antibiotic use before hospital admis

Study finds antibiotics combat gut bacteria that contribute to the pathogenesis of COVID-19

byWileyChest images of completely vaccinated sick moderate patients with SARS-CoV-2. Panel A-D: Four cases of vaccinated patients with pneumonia, no previous antibiotic use before hospital admis
Five-day antibiotic course noninferior for pediatric febrile UTI

Five-day antibiotic course noninferior for pediatric febrile UTI

by Elana GotkineFor young children with febrile urinary tract infection (fUTI), a five-day amoxicillin-clavulanate course is noninferior to a 10-day course for recurrence of UTI within 30 days after c

Five-day antibiotic course noninferior for pediatric febrile UTI

by Elana GotkineFor young children with febrile urinary tract infection (fUTI), a five-day amoxicillin-clavulanate course is noninferior to a 10-day course for recurrence of UTI within 30 days after c
Drug development advances in beneficial loss-of-function mutation targets validated by human genetics

Drug development advances in beneficial loss-of-function mutation targets validated by human genetics

by Sichuan International Medical Exchange and Promotion AssociationTargets primarily include PCSK9, ANGPTL3, HSD17B13, KHK, ASGR1, GPR75, CIDEB, and INHBE. Drug types primarily include small molecules

Drug development advances in beneficial loss-of-function mutation targets validated by human genetics

by Sichuan International Medical Exchange and Promotion AssociationTargets primarily include PCSK9, ANGPTL3, HSD17B13, KHK, ASGR1, GPR75, CIDEB, and INHBE. Drug types primarily include small molecules
Dicer enzyme cuts down on fats

Dicer enzyme cuts down on fats

by Ludwig Maximilian University of MunichDicer knockout in macrophages (right) accelerates atherosclerosis. Credit: Yuanyuan Wei, LMUThe enzyme Dicer cleaves long precursors into short RNA molecu

Dicer enzyme cuts down on fats

by Ludwig Maximilian University of MunichDicer knockout in macrophages (right) accelerates atherosclerosis. Credit: Yuanyuan Wei, LMUThe enzyme Dicer cleaves long precursors into short RNA molecu
Researchers help design easy-to-open, child-resistant medicine bottle

Researchers help design easy-to-open, child-resistant medicine bottle

by Abby Robinson,Georgia Institute of TechnologyEquipment used by Georgia Tech Research Institute (GTRI) product design researchers measures the forces required to open prescription medicine con

Researchers help design easy-to-open, child-resistant medicine bottle

by Abby Robinson,Georgia Institute of TechnologyEquipment used by Georgia Tech Research Institute (GTRI) product design researchers measures the forces required to open prescription medicine con
Prolonged use of certain hormone drugs linked to increased brain tumor risk

Prolonged use of certain hormone drugs linked to increased brain tumor risk

by British Medical JournalMeningiomas are graded by microscopic appearance, rate of growth and tendency to invade other tissues. Credit: National Cancer InstituteProlonged use of certain progesto

Prolonged use of certain hormone drugs linked to increased brain tumor risk

by British Medical JournalMeningiomas are graded by microscopic appearance, rate of growth and tendency to invade other tissues. Credit: National Cancer InstituteProlonged use of certain progesto
Many antibiotic courses for common infections not in line with guidelines

Many antibiotic courses for common infections not in line with guidelines

by British Medical JournalCredit: CC0 Public DomainMany antibiotic courses prescribed for common infections treated in English primary care (general practices and community services) exceed the r

Many antibiotic courses for common infections not in line with guidelines

by British Medical JournalCredit: CC0 Public DomainMany antibiotic courses prescribed for common infections treated in English primary care (general practices and community services) exceed the r
New data shows prevalence of Premenstrual Dysphoric Disorder (PMDD)

New data shows prevalence of Premenstrual Dysphoric Disorder (PMDD)

New data shows prevalence of Premenstrual Dysphoric Disorder (PMDD)HEALTHMEDICAL SCIENCESMENTAL HEALTHRESEARCH29 January 2024Around 1.6% of women and girls have symptomatic Premenstrual Dysphoric Diso

New data shows prevalence of Premenstrual Dysphoric Disorder (PMDD)

New data shows prevalence of Premenstrual Dysphoric Disorder (PMDD)HEALTHMEDICAL SCIENCESMENTAL HEALTHRESEARCH29 January 2024Around 1.6% of women and girls have symptomatic Premenstrual Dysphoric Diso
Researchers present playbook of best practices for cancer team science in the modern era

Researchers present playbook of best practices for cancer team science in the modern era

by Break Through CancerThe Hallmarks of Cancer Collaboration. Based on Hanahan and Weinberg's seminal "Hallmarks of Cancer," this illustration proposes six Hallmarks of Cancer Collaborat

Researchers present playbook of best practices for cancer team science in the modern era

by Break Through CancerThe Hallmarks of Cancer Collaboration. Based on Hanahan and Weinberg's seminal "Hallmarks of Cancer," this illustration proposes six Hallmarks of Cancer Collaborat
Poison center calls related to injected weight-loss drugs up 1,500%

Poison center calls related to injected weight-loss drugs up 1,500%

by Nancy Clanton, The Atlanta Journal-ConstitutionCredit: Pixabay/CC0 Public DomainAmerica's Poison Centers reported nearly 3,000 calls this year involving the weight loss drug semaglutide—a 15-fo

Poison center calls related to injected weight-loss drugs up 1,500%

by Nancy Clanton, The Atlanta Journal-ConstitutionCredit: Pixabay/CC0 Public DomainAmerica's Poison Centers reported nearly 3,000 calls this year involving the weight loss drug semaglutide—a 15-fo
FoxO6-mediated ApoC3 upregulation promotes hepatic steatosis and hyperlipidemia in HFD aged rats: Study

FoxO6-mediated ApoC3 upregulation promotes hepatic steatosis and hyperlipidemia in HFD aged rats: Study

by Impact Journals LLCAging-related serum changes in insulin resistance and lipogenesis. (A) Glucose levels, (B) insulin levels, and (C) HOMA-IR scores were determined. (D) FFA (free fatty acid), (E)

FoxO6-mediated ApoC3 upregulation promotes hepatic steatosis and hyperlipidemia in HFD aged rats: Study

by Impact Journals LLCAging-related serum changes in insulin resistance and lipogenesis. (A) Glucose levels, (B) insulin levels, and (C) HOMA-IR scores were determined. (D) FFA (free fatty acid), (E)