Experimental compound extends life in amyotrophic lateral sclerosis mouse model

FEBRUARY 6, 2024byUT Southwestern Medical CenterMAP4K interactome and the effect on RANGAP1 subcellular distribution.AWestern-blotting analysis of proteins after proximity labeling i

Updated on: March 25,2024

Experimental compound extends life in amyotrophic lateral sclerosis mouse model

FEBRUARY 6, 2024byUT Southwestern Medical CenterMAP4K interactome and the effect on RANGAP1 subcellular distribution.AWestern-blotting analysis of proteins after proximity labeling i

Updated on:March 25,2024

Research uncovers mechanism behind stubborn memories

BRAIN HEALTHMEDICAL SCIENCESMENTAL HEALTHNEUROSCIENCERESEARCH18 January 2024Researchers from the Medical Research Council Brain Network Dynamics Unit at the University of Oxford and the Nuffield Depar

Updated on: March 11,2024

Research uncovers mechanism behind stubborn memories

BRAIN HEALTHMEDICAL SCIENCESMENTAL HEALTHNEUROSCIENCERESEARCH18 January 2024Researchers from the Medical Research Council Brain Network Dynamics Unit at the University of Oxford and the Nuffield Depar

Updated on:March 11,2024

Zinc deficiency promotes Acinetobacter lung infection, mouse study shows

byVanderbilt University Medical CenterZn-deficient mice produce higher levels of IL-13. Credit:Nature Microbiology(2024). DOI: 10.1038/s41564-024-01849-wDietary zinc deficiency promo

Updated on: December 03,2024

Zinc deficiency promotes Acinetobacter lung infection, mouse study shows

byVanderbilt University Medical CenterZn-deficient mice produce higher levels of IL-13. Credit:Nature Microbiology(2024). DOI: 10.1038/s41564-024-01849-wDietary zinc deficiency promo

Updated on:December 03,2024

Enhancing hypoxia-activated prodrug anticancer therapy

by Science China PressOn the top, (a) Chemical structure of TPZP. On the bottom, (b) Schematic diagram of combined therapy. Art by Michael Rothman. Art by Zhaohui Tang. Credit: Science China Pres

Updated on: April 06,2024

Enhancing hypoxia-activated prodrug anticancer therapy

by Science China PressOn the top, (a) Chemical structure of TPZP. On the bottom, (b) Schematic diagram of combined therapy. Art by Michael Rothman. Art by Zhaohui Tang. Credit: Science China Pres

Updated on:April 06,2024

Interactions between flu subtypes found to predict epidemic severity more than virus evolution

by Emily PackerEmily Packer,eLifeAntigenic and genetic evolution of seasonal influenza A(H3N2) viruses, 1997—2019. A-B.Temporal phylogenies of hemagglutinin (H3) and neuraminidase (N2) gene segm

Updated on: March 13,2024

Interactions between flu subtypes found to predict epidemic severity more than virus evolution

by Emily PackerEmily Packer,eLifeAntigenic and genetic evolution of seasonal influenza A(H3N2) viruses, 1997—2019. A-B.Temporal phylogenies of hemagglutinin (H3) and neuraminidase (N2) gene segm

Updated on:March 13,2024

The First CRISPR Gene Therapy Is Here

Updated on: September 02,2024

The First CRISPR Gene Therapy Is Here

Updated on:September 02,2024

Multi-generational toxicant exposures show cumulative, inherited health effects

JANUARY 23, 2024byWashington State UniversityDMR identification. The number of DMRs found using different P-value cutoff thresholds. The All-Window column shows all DMRs. The Multiple Window col

Updated on: March 15,2024

Multi-generational toxicant exposures show cumulative, inherited health effects

JANUARY 23, 2024byWashington State UniversityDMR identification. The number of DMRs found using different P-value cutoff thresholds. The All-Window column shows all DMRs. The Multiple Window col

Updated on:March 15,2024

Metabolic remodeling in endothelial cells and macrophages contributes to plaque instability and vulnerability

Updated on: October 02,2024

Metabolic remodeling in endothelial cells and macrophages contributes to plaque instability and vulnerability

Updated on:October 02,2024

Extra fingers and hearts: Pinpointing changes to our genetic instructions that disrupt development

by Mario Aguilera,University of California - San DiegoChanging the instructions for development: Single-letter changes to genomes led to the formation of an extra digit (right). Credit: Fabian L

Updated on: March 14,2024

Extra fingers and hearts: Pinpointing changes to our genetic instructions that disrupt development

by Mario Aguilera,University of California - San DiegoChanging the instructions for development: Single-letter changes to genomes led to the formation of an extra digit (right). Credit: Fabian L

Updated on:March 14,2024

Study with over 11,000 individuals of African descent finds genetic variants linked to glaucoma

byCell PressDiscovery of known and previously undescribed loci from the discovery mega-analysis of African ancestry individuals. Credit: Cell/Verma et al.Glaucoma is the leading cause of irrever

Updated on: March 14,2024

Study with over 11,000 individuals of African descent finds genetic variants linked to glaucoma

byCell PressDiscovery of known and previously undescribed loci from the discovery mega-analysis of African ancestry individuals. Credit: Cell/Verma et al.Glaucoma is the leading cause of irrever

Updated on:March 14,2024

Familial Alzheimer's disease transferred via bone marrow transplant in mice

byCell PressA painting representing Alzheimer's transmissibility as reported in thisStem Cell Reportsstudy. Credit: Chaahat SinghFamilial Alzheimer's disease can be transferr

Updated on: March 30,2024

Familial Alzheimer's disease transferred via bone marrow transplant in mice

byCell PressA painting representing Alzheimer's transmissibility as reported in thisStem Cell Reportsstudy. Credit: Chaahat SinghFamilial Alzheimer's disease can be transferr

Updated on:March 30,2024

Team develops a single-nucleus resolution atlas of white adipose tissue in different depots

FEBRUARY 5, 2024by Higher Education PressWorkflow to perform snRNA-seq of different WAT depots. The nuclei were derived from subcutaneous (S), epididymal (E), mesenteric (M), peri-nephritic (N), and p

Updated on: March 28,2024

Team develops a single-nucleus resolution atlas of white adipose tissue in different depots

FEBRUARY 5, 2024by Higher Education PressWorkflow to perform snRNA-seq of different WAT depots. The nuclei were derived from subcutaneous (S), epididymal (E), mesenteric (M), peri-nephritic (N), and p

Updated on:March 28,2024