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Breakthroughs
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A new vision for AAV-delivered gene therapies

A new vision for AAV-delivered gene therapies

by Benjamin Boettner,Harvard UniversityAAVs with TLR9-inhibitory sequences incorporated into their genomes allowed significantly higher expression of a linked fluorescent reporter gene in the mo

A new vision for AAV-delivered gene therapies

by Benjamin Boettner,Harvard UniversityAAVs with TLR9-inhibitory sequences incorporated into their genomes allowed significantly higher expression of a linked fluorescent reporter gene in the mo
Study finds antibiotics combat gut bacteria that contribute to the pathogenesis of COVID-19

Study finds antibiotics combat gut bacteria that contribute to the pathogenesis of COVID-19

byWileyChest images of completely vaccinated sick moderate patients with SARS-CoV-2. Panel A-D: Four cases of vaccinated patients with pneumonia, no previous antibiotic use before hospital admis

Study finds antibiotics combat gut bacteria that contribute to the pathogenesis of COVID-19

byWileyChest images of completely vaccinated sick moderate patients with SARS-CoV-2. Panel A-D: Four cases of vaccinated patients with pneumonia, no previous antibiotic use before hospital admis
Study confirms how RNA chemical modifications benefit HIV-1

Study confirms how RNA chemical modifications benefit HIV-1

by Emily Caldwell,The Ohio State UniversityHIV-1 Virus. Credit: J Roberto Trujillo/WikipediaA chemical modification in the HIV-1 RNA genome whose function has been a matter of scientific debate

Study confirms how RNA chemical modifications benefit HIV-1

by Emily Caldwell,The Ohio State UniversityHIV-1 Virus. Credit: J Roberto Trujillo/WikipediaA chemical modification in the HIV-1 RNA genome whose function has been a matter of scientific debate
Study finds Paxlovid treatment does not reduce risk of long COVID

Study finds Paxlovid treatment does not reduce risk of long COVID

byUniversity of California, San FranciscoIn all models, treatment with oral nirmatrelvir was not associated with lower odds of patient reported Long COVID symptoms with confidence intervals that

Study finds Paxlovid treatment does not reduce risk of long COVID

byUniversity of California, San FranciscoIn all models, treatment with oral nirmatrelvir was not associated with lower odds of patient reported Long COVID symptoms with confidence intervals that
Patients with common form of acute myeloid leukemia report better quality of life when treated with quizartinib

Patients with common form of acute myeloid leukemia report better quality of life when treated with quizartinib

byUniversity of Miami Leonard M. Miller School of MedicineAcute myelocytic leukemia (AML). Credit: Unsplash/CC0 Public DomainIn a study led by researchers at Sylvester Comprehensive Cancer Cente

Patients with common form of acute myeloid leukemia report better quality of life when treated with quizartinib

byUniversity of Miami Leonard M. Miller School of MedicineAcute myelocytic leukemia (AML). Credit: Unsplash/CC0 Public DomainIn a study led by researchers at Sylvester Comprehensive Cancer Cente
Wound healing checked in real time with electronic suture

Wound healing checked in real time with electronic suture

by DGIST (Daegu Gyeongbuk Institute of Science and Technology)Schematic illustrations of (a) the Au-based fiber electrode serves as a base electrode for the working and reference electrodes, (c) the P

Wound healing checked in real time with electronic suture

by DGIST (Daegu Gyeongbuk Institute of Science and Technology)Schematic illustrations of (a) the Au-based fiber electrode serves as a base electrode for the working and reference electrodes, (c) the P
Call to reduce repeat 'within-episode' antibiotic prescriptions for respiratory tract infections in primary care

Call to reduce repeat 'within-episode' antibiotic prescriptions for respiratory tract infections in primary care

byUniversity of BristolCredit: Unsplash/CC0 Public DomainA new study exploring the use of repeat antibiotic prescriptions for the same respiratory tract infection (RTI) episode—known as repeat &

Call to reduce repeat 'within-episode' antibiotic prescriptions for respiratory tract infections in primary care

byUniversity of BristolCredit: Unsplash/CC0 Public DomainA new study exploring the use of repeat antibiotic prescriptions for the same respiratory tract infection (RTI) episode—known as repeat &
These programs put unused prescription drugs in the hands of patients in need

These programs put unused prescription drugs in the hands of patients in need

by Kate Ruder, KFF Health NewsCredit: Pixabay/CC0 Public DomainOn a recent November evening, Angie Phoenix waited at a pharmacy here in Colorado's second-largest city to pick up prescription drugs

These programs put unused prescription drugs in the hands of patients in need

by Kate Ruder, KFF Health NewsCredit: Pixabay/CC0 Public DomainOn a recent November evening, Angie Phoenix waited at a pharmacy here in Colorado's second-largest city to pick up prescription drugs
Researchers develop mixture of compounds to help preserve organs before transplantation

Researchers develop mixture of compounds to help preserve organs before transplantation

byWileyIndividual CPA toxicity assay (A) and identification of best performing external CPAs cocktail capable of retaining larvae viability after 22 min of storage at −10°C when immersed in CPAs

Researchers develop mixture of compounds to help preserve organs before transplantation

byWileyIndividual CPA toxicity assay (A) and identification of best performing external CPAs cocktail capable of retaining larvae viability after 22 min of storage at −10°C when immersed in CPAs
Study identifies factors associated with long-term use of FDA-approved anti-obesity medications

Study identifies factors associated with long-term use of FDA-approved anti-obesity medications

byCleveland ClinicPercentage of patients who were persistent with antiobesity medication (AOM) at early stage, medium term, and long term, by AOM agent. [Color figure can be viewed atwiley

Study identifies factors associated with long-term use of FDA-approved anti-obesity medications

byCleveland ClinicPercentage of patients who were persistent with antiobesity medication (AOM) at early stage, medium term, and long term, by AOM agent. [Color figure can be viewed atwiley
Researchers produce grafts that replicate the human ear

Researchers produce grafts that replicate the human ear

by Weill Cornell Medical CollegePictured is the intricate, left-ear plastic scaffold that was created on a 3D printer based on data from a person's ear, anterior view (left) and posterior vie

Researchers produce grafts that replicate the human ear

by Weill Cornell Medical CollegePictured is the intricate, left-ear plastic scaffold that was created on a 3D printer based on data from a person's ear, anterior view (left) and posterior vie