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Breakthroughs
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Imetelstat leads to durable red blood cell transfusion independence

Imetelstat leads to durable red blood cell transfusion independence

by Elana GotkineFor heavily transfused patients with lower-risk myelodysplastic syndromes (LR-MDS) who are not responding to or are ineligible for erythropoiesis-stimulating agents (ESAs), the competi

Imetelstat leads to durable red blood cell transfusion independence

by Elana GotkineFor heavily transfused patients with lower-risk myelodysplastic syndromes (LR-MDS) who are not responding to or are ineligible for erythropoiesis-stimulating agents (ESAs), the competi
New findings suggest life span can be increased by making cells less efficient at producing energy

New findings suggest life span can be increased by making cells less efficient at producing energy

by Pennington Biomedical Research CenterChristopher Axelrod, Director, Integrated Physiology and Molecular Medicine Laboratory at Pennington Biomedical Research Center. Credit: PBRCA newstudy&nb

New findings suggest life span can be increased by making cells less efficient at producing energy

by Pennington Biomedical Research CenterChristopher Axelrod, Director, Integrated Physiology and Molecular Medicine Laboratory at Pennington Biomedical Research Center. Credit: PBRCA newstudy&nb
Targeting the mRNA of 'undruggable' proteins in the fight against Parkinson's disease

Targeting the mRNA of 'undruggable' proteins in the fight against Parkinson's disease

JANUARY 8, 2024REPORTby Justin Jackson , Medical XpressCredit: Pixabay/CC0 Public DomainResearchers at the Scripps Research Institute, Florida, have developed a new method to counteract α-synucl

Targeting the mRNA of 'undruggable' proteins in the fight against Parkinson's disease

JANUARY 8, 2024REPORTby Justin Jackson , Medical XpressCredit: Pixabay/CC0 Public DomainResearchers at the Scripps Research Institute, Florida, have developed a new method to counteract α-synucl
Biological engineers discover why a promising drug failed in clinical trials

Biological engineers discover why a promising drug failed in clinical trials

by Anne Trafton,Massachusetts Institute of TechnologyRheumatoid arthritis, which afflicts more than 1 million Americans, is an autoimmune disorder that produces swollen and painful joints, prima

Biological engineers discover why a promising drug failed in clinical trials

by Anne Trafton,Massachusetts Institute of TechnologyRheumatoid arthritis, which afflicts more than 1 million Americans, is an autoimmune disorder that produces swollen and painful joints, prima
Could artificial intelligence help or hurt medical research articles?

Could artificial intelligence help or hurt medical research articles?

FEBRUARY 6, 2024byIndiana University School of MedicineOverview of experimental study design employed to examine the utility of using ChatGPT to write scientific review articles about the inters

Could artificial intelligence help or hurt medical research articles?

FEBRUARY 6, 2024byIndiana University School of MedicineOverview of experimental study design employed to examine the utility of using ChatGPT to write scientific review articles about the inters
Flies fed restricted diet in early adulthood found to live longer

Flies fed restricted diet in early adulthood found to live longer

byRIKENA model of lifespan extension by early Met restriction. Methionine restriction in young flies can induce MsrA and decrease MetSO level, leading to lifespan extension. This nutritional res

Flies fed restricted diet in early adulthood found to live longer

byRIKENA model of lifespan extension by early Met restriction. Methionine restriction in young flies can induce MsrA and decrease MetSO level, leading to lifespan extension. This nutritional res
Researchers define new subtypes of common brain disorder

Researchers define new subtypes of common brain disorder

by Mark Reynolds,Washington University School of MedicineAn MRI scan shows a Chiari type-1 malformation, in which the cerebellum extends beyond the gap in the skull where it connects to the spin

Researchers define new subtypes of common brain disorder

by Mark Reynolds,Washington University School of MedicineAn MRI scan shows a Chiari type-1 malformation, in which the cerebellum extends beyond the gap in the skull where it connects to the spin
Scientists analyze virus protein structure to advance RSV vaccines

Scientists analyze virus protein structure to advance RSV vaccines

byThe Scripps Research InstituteComparative in vitro characterization of previously reported RSV-F designs. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-54287-xIn most

Scientists analyze virus protein structure to advance RSV vaccines

byThe Scripps Research InstituteComparative in vitro characterization of previously reported RSV-F designs. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-54287-xIn most
Researchers advance understanding of Parkinson's disease

Researchers advance understanding of Parkinson's disease

byUniversity of GalwaySchematic representation of the experimental design and procedures followed in this study. The study was designed for the region-specific and temporal characterization of t

Researchers advance understanding of Parkinson's disease

byUniversity of GalwaySchematic representation of the experimental design and procedures followed in this study. The study was designed for the region-specific and temporal characterization of t
Using deep learning techniques to improve liver disease diagnosis and treatment

Using deep learning techniques to improve liver disease diagnosis and treatment

byGeorgia Institute of TechnologyComparison of the workflow between the proposed deep learning-based image quality classification and the traditional visual inspection. Credit:Journal of M

Using deep learning techniques to improve liver disease diagnosis and treatment

byGeorgia Institute of TechnologyComparison of the workflow between the proposed deep learning-based image quality classification and the traditional visual inspection. Credit:Journal of M
Study highlights impact of aldehydes on DNA damage and aging

Study highlights impact of aldehydes on DNA damage and aging

byNagoya UniversityHistones are crosslinked with DNA (histone-DPC) following formaldehyde exposure, leading to the malfunction of cellular processes such as transcription. Credit: Reiko Matsushi

Study highlights impact of aldehydes on DNA damage and aging

byNagoya UniversityHistones are crosslinked with DNA (histone-DPC) following formaldehyde exposure, leading to the malfunction of cellular processes such as transcription. Credit: Reiko Matsushi