Study identifies novel mechanism of glucose sensing by adipocytes in regulating thermogenesis and energy metabolism

by Liu Jia,Chinese Academy of SciencesThe proposed model for glucose sensing via CREBZF in the regulation of thermogenesis and energy homeostasis in adipose tissues. Targeting CREBZF may provide

Updated on: April 28,2024

Study identifies novel mechanism of glucose sensing by adipocytes in regulating thermogenesis and energy metabolism

by Liu Jia,Chinese Academy of SciencesThe proposed model for glucose sensing via CREBZF in the regulation of thermogenesis and energy homeostasis in adipose tissues. Targeting CREBZF may provide

Updated on:April 28,2024

Researchers make mice a more powerful tool to study a wide range of human diseases

byJackson LaboratoryThe new protocol coaxes mouse stem cells to develop across multiple strains of mice, not just strain 129. This enables researchers to identify which strain best resemebles ce

Updated on: April 06,2024

Researchers make mice a more powerful tool to study a wide range of human diseases

byJackson LaboratoryThe new protocol coaxes mouse stem cells to develop across multiple strains of mice, not just strain 129. This enables researchers to identify which strain best resemebles ce

Updated on:April 06,2024

Clinical presentation of IDDMSSD syndrome likely associated with molecular location of mutation in PAK1 gene

by Texas Children's HospitalCredit: Pixabay/CC0 Public DomainA recent study from Texas Children's Hospital and Baylor College of Medicine has expanded the clinical spectrum of a new epileptic

Updated on: April 01,2024

Clinical presentation of IDDMSSD syndrome likely associated with molecular location of mutation in PAK1 gene

by Texas Children's HospitalCredit: Pixabay/CC0 Public DomainA recent study from Texas Children's Hospital and Baylor College of Medicine has expanded the clinical spectrum of a new epileptic

Updated on:April 01,2024

Materiobiology: Advances in aging bone regeneration material development

byScience China PressThe new development process for aging bone regeneration materials focuses on in-depth research of dysfunctional mechanisms, the development of a biomaterial 'toolbox&#39

Updated on: April 27,2024

Materiobiology: Advances in aging bone regeneration material development

byScience China PressThe new development process for aging bone regeneration materials focuses on in-depth research of dysfunctional mechanisms, the development of a biomaterial 'toolbox&#39

Updated on:April 27,2024

Scientists identify mutations that cause inherited kidney disease

byAtrium Health Wake Forest BaptistCredit:Kidney International(2023). DOI: 10.1016/j.kint.2023.11.021Genetic changes or mutations can cause hereditary kidney disease, which can event

Updated on: March 13,2024

Scientists identify mutations that cause inherited kidney disease

byAtrium Health Wake Forest BaptistCredit:Kidney International(2023). DOI: 10.1016/j.kint.2023.11.021Genetic changes or mutations can cause hereditary kidney disease, which can event

Updated on:March 13,2024

Research suggests fine-tuning of specific excitatory synapse traits could lead to new brain disease treatments

by DGIST (Daegu Gyeongbuk Institute of Science and Technology)Profiling of LAR-RPTP microexon expression repertoires by targeted deep RNA sequencing Credit:Nature Communications(2024). DOI

Updated on: March 30,2024

Research suggests fine-tuning of specific excitatory synapse traits could lead to new brain disease treatments

by DGIST (Daegu Gyeongbuk Institute of Science and Technology)Profiling of LAR-RPTP microexon expression repertoires by targeted deep RNA sequencing Credit:Nature Communications(2024). DOI

Updated on:March 30,2024

How to make mRNA therapeutics safe from the start

FEBRUARY 28, 2024by Cynthia McCormick Hibbert,Northeastern UniversityScientists eager to harness mRNA technology to fight cancer and more need to find ways to test early for safety, Northeastern

Updated on: March 25,2024

How to make mRNA therapeutics safe from the start

FEBRUARY 28, 2024by Cynthia McCormick Hibbert,Northeastern UniversityScientists eager to harness mRNA technology to fight cancer and more need to find ways to test early for safety, Northeastern

Updated on:March 25,2024

CBD products don't ease pain and are potentially harmful, study finds

by Vittoria D'Alessio,University of BathCredit: Unsplash/CC0 Public DomainThere is no evidence that CBD products reduce chronic pain, and taking them is a waste of money and potentially harm

Updated on: March 28,2024

CBD products don't ease pain and are potentially harmful, study finds

by Vittoria D'Alessio,University of BathCredit: Unsplash/CC0 Public DomainThere is no evidence that CBD products reduce chronic pain, and taking them is a waste of money and potentially harm

Updated on:March 28,2024

New tool improves the search for genes that cause diseases

byUniversity of ChicagoDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHA new statistical tool developed by researchers at the University of Ch

Updated on: April 26,2024

New tool improves the search for genes that cause diseases

byUniversity of ChicagoDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHA new statistical tool developed by researchers at the University of Ch

Updated on:April 26,2024

How transcription factors influence insulin-producing beta cells

JANUARY 31, 2024by Melissa Rohman,Northwestern UniversityCredit:Cell Metabolism(2024). DOI: 10.1016/j.cmet.2023.11.018A recent study from the laboratory of Joseph Bass, MD, Ph.D., th

Updated on: March 30,2024

How transcription factors influence insulin-producing beta cells

JANUARY 31, 2024by Melissa Rohman,Northwestern UniversityCredit:Cell Metabolism(2024). DOI: 10.1016/j.cmet.2023.11.018A recent study from the laboratory of Joseph Bass, MD, Ph.D., th

Updated on:March 30,2024

Scientists discover a potential way to repair synapses damaged in Alzheimer's disease

FEBRUARY 1, 2024by Buck Institute for Research on AgingThe art depicts the recovery of the functional plasticity at synapses on neurons despite tau-induced toxicity in the brain. Credit: Larissa Brown

Updated on: March 25,2024

Scientists discover a potential way to repair synapses damaged in Alzheimer's disease

FEBRUARY 1, 2024by Buck Institute for Research on AgingThe art depicts the recovery of the functional plasticity at synapses on neurons despite tau-induced toxicity in the brain. Credit: Larissa Brown

Updated on:March 25,2024

New web portal empowers drug discovery, systems-level analysis of critical kinase-substrate interactions

byThe Mount Sinai HospitalKiNet functionalities. Credit:npj Systems Biology and Applications(2024). DOI: 10.1038/s41540-024-00442-5Researchers from the Icahn School of Medicine at Mo

Updated on: October 21,2024

New web portal empowers drug discovery, systems-level analysis of critical kinase-substrate interactions

byThe Mount Sinai HospitalKiNet functionalities. Credit:npj Systems Biology and Applications(2024). DOI: 10.1038/s41540-024-00442-5Researchers from the Icahn School of Medicine at Mo

Updated on:October 21,2024