Obesity alters molecular architecture of liver cells. Repairing structure reverses metabolic disease

by Harvard School of Public HealthThe endoplasmic reticulum (ER) is white and lipid droplets appear yellow In this three-dimensional image of the interior of a diseased mouse liver cell created b

Updated on: January 31,2024

Obesity alters molecular architecture of liver cells. Repairing structure reverses metabolic disease

by Harvard School of Public HealthThe endoplasmic reticulum (ER) is white and lipid droplets appear yellow In this three-dimensional image of the interior of a diseased mouse liver cell created b

Updated on:January 31,2024

The mere sight of a meal triggers an inflammatory response in the brain

by University of BaselCredit: CC0 Public DomainEven before carbohydrates reach the bloodstream, the very sight and smell of a meal trigger the release of insulin. For the first time, researchers

Updated on: February 05,2024

The mere sight of a meal triggers an inflammatory response in the brain

by University of BaselCredit: CC0 Public DomainEven before carbohydrates reach the bloodstream, the very sight and smell of a meal trigger the release of insulin. For the first time, researchers

Updated on:February 05,2024

Dietary pyruvate targets cytosolic phospholipase A2 to mitigate inflammation and obesity in mice

by Higher Education PressThe mechanism of action of pyruvate by targeting cPLA2 and inhibiting cPLA2-mediated downstream signaling. Credit: Sadaf Hasan, Nabil Ghani, Xiangli Zhao, Julia Good, Amanda H

Updated on: July 25,2024

Dietary pyruvate targets cytosolic phospholipase A2 to mitigate inflammation and obesity in mice

by Higher Education PressThe mechanism of action of pyruvate by targeting cPLA2 and inhibiting cPLA2-mediated downstream signaling. Credit: Sadaf Hasan, Nabil Ghani, Xiangli Zhao, Julia Good, Amanda H

Updated on:July 25,2024

Intermittent fasting improves Alzheimer's pathology in mouse model

Intermittent fasting improves Alzheimer's pathology in mouse modelbyUniversity of California - San DiegoThis confocal microscopy image shows amyloid plaques (blue and red) in the brain of a

Updated on: January 24,2024

Intermittent fasting improves Alzheimer's pathology in mouse model

Intermittent fasting improves Alzheimer's pathology in mouse modelbyUniversity of California - San DiegoThis confocal microscopy image shows amyloid plaques (blue and red) in the brain of a

Updated on:January 24,2024

Pregnant women with obesity and diabetes may be more likely to have a child with ADHD

by The Endocrine SocietyCredit: Pixabay/CC0 Public DomainChildren of women with gestational diabetes and obesity may be twice as likely to develop attention-deficit/hyperactivity disorder (ADHD)

Updated on: February 05,2024

Pregnant women with obesity and diabetes may be more likely to have a child with ADHD

by The Endocrine SocietyCredit: Pixabay/CC0 Public DomainChildren of women with gestational diabetes and obesity may be twice as likely to develop attention-deficit/hyperactivity disorder (ADHD)

Updated on:February 05,2024

'Tiny but mighty' gene fragments are crucial for maintaining blood glucose levels, shows study

by Center for Genomic RegulationPancreatic islets in mice, specialized tissues that host beta cells. On the left, a healthy pancreatic islet is shown with its typical morphology with alpha cells in th

Updated on: February 19,2024

'Tiny but mighty' gene fragments are crucial for maintaining blood glucose levels, shows study

by Center for Genomic RegulationPancreatic islets in mice, specialized tissues that host beta cells. On the left, a healthy pancreatic islet is shown with its typical morphology with alpha cells in th

Updated on:February 19,2024

Research boosts case for new gene therapy to treat severe form of epilepsy

by Josh Barney,University of VirginiaCredit: CC0 Public DomainResearch from the University of Virginia School of Medicine suggests how a newly developed gene therapy can treat Dravet syndrome, a

Updated on: February 21,2024

Research boosts case for new gene therapy to treat severe form of epilepsy

by Josh Barney,University of VirginiaCredit: CC0 Public DomainResearch from the University of Virginia School of Medicine suggests how a newly developed gene therapy can treat Dravet syndrome, a

Updated on:February 21,2024

Extracellular vesicles offer new insights into treating endocrine disorders

by The Endocrine SocietyCredit: Pixabay/CC0 Public DomainIn a new Scientific Statement released today, the Endocrine Society describes the importance of extracellular vesicles as a new research t

Updated on: February 19,2024

Extracellular vesicles offer new insights into treating endocrine disorders

by The Endocrine SocietyCredit: Pixabay/CC0 Public DomainIn a new Scientific Statement released today, the Endocrine Society describes the importance of extracellular vesicles as a new research t

Updated on:February 19,2024

Moderation may disrupt addictive nature of wireless mobile devices and adverse health outcomes

by The Endocrine SocietyCredit: CC0 Public DomainEncouraging moderation, balance and real-life engagement coupled with education may combat the overuse of wireless mobile devices and subsequent a

Updated on: February 21,2024

Moderation may disrupt addictive nature of wireless mobile devices and adverse health outcomes

by The Endocrine SocietyCredit: CC0 Public DomainEncouraging moderation, balance and real-life engagement coupled with education may combat the overuse of wireless mobile devices and subsequent a

Updated on:February 21,2024

Study identifies effects of secretin on cardiorenal function

by American Physiological SocietyMyocardial glucose uptake results. A: representative [18F]FDG PET/CT vertical long axis images showing Ki of the heart after secretin and placebo infusions (n = 1

Updated on: February 21,2024

Study identifies effects of secretin on cardiorenal function

by American Physiological SocietyMyocardial glucose uptake results. A: representative [18F]FDG PET/CT vertical long axis images showing Ki of the heart after secretin and placebo infusions (n = 1

Updated on:February 21,2024

'Energy crisis' in fat cells behind inflammation associated with obesity

by Karolinska InstitutetFig. 1: Obesity is associated with altered phosphocreatine/creatine metabolism in human WAT. a, Polar metabolites in subcutaneous WAT of obese (n = 13) and non-obese (NO,

Updated on: February 03,2024

'Energy crisis' in fat cells behind inflammation associated with obesity

by Karolinska InstitutetFig. 1: Obesity is associated with altered phosphocreatine/creatine metabolism in human WAT. a, Polar metabolites in subcutaneous WAT of obese (n = 13) and non-obese (NO,

Updated on:February 03,2024

Study reveals how insulin-producing cells work together to respond to metabolic demands

by Emily Packer, George Litchfield,eLifeModulation of individual IPCs by aminergic and peptidergic neurons in patch-clamp recordings. Credit:eLife(2024). DOI: 10.7554/eLife.99548.1Sc

Updated on: September 25,2024

Study reveals how insulin-producing cells work together to respond to metabolic demands

by Emily Packer, George Litchfield,eLifeModulation of individual IPCs by aminergic and peptidergic neurons in patch-clamp recordings. Credit:eLife(2024). DOI: 10.7554/eLife.99548.1Sc

Updated on:September 25,2024