Modeling diabetes in minipigs for more accurate testing of potential cell therapies

byKyoto UniversityCredit:Cell Transplantation(2024). DOI: 10.1177/09636897241288932Since the discovery of human iPS cells, a principal goal for researchers worldwide has been to use

Updated on: October 31,2024

Modeling diabetes in minipigs for more accurate testing of potential cell therapies

byKyoto UniversityCredit:Cell Transplantation(2024). DOI: 10.1177/09636897241288932Since the discovery of human iPS cells, a principal goal for researchers worldwide has been to use

Updated on:October 31,2024

Humanized mice reveal arsenic may raise diabetes risk only for males

by Krishna Ramanujan,Cornell UniversityMeasuring arsenic in liver and adipose tissue of humanized and wild-type mice. (A) Arsenical quantification in isolated liver of mice (WT male, n=5; WT fem

Updated on: March 14,2024

Humanized mice reveal arsenic may raise diabetes risk only for males

by Krishna Ramanujan,Cornell UniversityMeasuring arsenic in liver and adipose tissue of humanized and wild-type mice. (A) Arsenical quantification in isolated liver of mice (WT male, n=5; WT fem

Updated on:March 14,2024

Inhibiting somatostatin may prevent dangerous blood glucose drops in type 1 diabetes

byUniversity of GothenburgImpact of T1D on plasma glucose and pancreatic insulin and glucagon contents in NOD mice. Credit:Nature Metabolism(2024). DOI: 10.1038/s42255-024-01139-zInh

Updated on: October 09,2024

Inhibiting somatostatin may prevent dangerous blood glucose drops in type 1 diabetes

byUniversity of GothenburgImpact of T1D on plasma glucose and pancreatic insulin and glucagon contents in NOD mice. Credit:Nature Metabolism(2024). DOI: 10.1038/s42255-024-01139-zInh

Updated on:October 09,2024

High aerobic fitness does not protect children from metabolic syndrome, study finds

by University of JyväskyläDifferences in V̇O2peakamong children with different numbers of cardiometabolic risk factors. The metabolic syndrome was defined using the modified National Choles

Updated on: February 21,2024

High aerobic fitness does not protect children from metabolic syndrome, study finds

by University of JyväskyläDifferences in V̇O2peakamong children with different numbers of cardiometabolic risk factors. The metabolic syndrome was defined using the modified National Choles

Updated on:February 21,2024

Obesity-related gut damage may worsen asthma symptoms

by Society for EndocrinologyCredit: Pixabay/CC0 Public DomainChanges in gut function caused by weight gain are associated with an increase in asthma severity, according to research to be presented at

Updated on: January 31,2024

Obesity-related gut damage may worsen asthma symptoms

by Society for EndocrinologyCredit: Pixabay/CC0 Public DomainChanges in gut function caused by weight gain are associated with an increase in asthma severity, according to research to be presented at

Updated on:January 31,2024

Could cholesterol explain why childhood obesity leads to early puberty?

by University of CopenhagenDietary cholesterol systemically promotes growth through insulin signaling(A) Larval growth on synthetic medium, reflected in pupal size, increases with increasing diet

Updated on: February 03,2024

Could cholesterol explain why childhood obesity leads to early puberty?

by University of CopenhagenDietary cholesterol systemically promotes growth through insulin signaling(A) Larval growth on synthetic medium, reflected in pupal size, increases with increasing diet

Updated on:February 03,2024

Identification of disease-causing proteins leads to new potential treatments for diseases like diabetes

by Queen Mary, University of LondonCredit: CC0 Public DomainNew research has identified hundreds of proteins that might contribute to the onset of common, chronic metabolic diseases such as type

Updated on: January 31,2024

Identification of disease-causing proteins leads to new potential treatments for diseases like diabetes

by Queen Mary, University of LondonCredit: CC0 Public DomainNew research has identified hundreds of proteins that might contribute to the onset of common, chronic metabolic diseases such as type

Updated on:January 31,2024

Excess calories during development may alter the brain and spur adult overeating

by Rutgers UniversityBNST→LHA connectivity is primarily GABAergic and is negatively correlated with early life growth rate. A. Experimental schematic. AAV-Syn-ChR2-eYFP was injected in BNST. B. E

Updated on: February 03,2024

Excess calories during development may alter the brain and spur adult overeating

by Rutgers UniversityBNST→LHA connectivity is primarily GABAergic and is negatively correlated with early life growth rate. A. Experimental schematic. AAV-Syn-ChR2-eYFP was injected in BNST. B. E

Updated on:February 03,2024

Study reveals obesity-related trigger that can lead to diabetes

by Washington University School of MedicineResearchers at Washington University School of Medicine in St. Louis have found that a defect in an enzyme called APT1 interferes with the ability to se

Updated on: February 21,2024

Study reveals obesity-related trigger that can lead to diabetes

by Washington University School of MedicineResearchers at Washington University School of Medicine in St. Louis have found that a defect in an enzyme called APT1 interferes with the ability to se

Updated on:February 21,2024

Is a longer reproductive lifespan good for your brain?

byAmerican Academy of NeurologyCredit: Pixabay/CC0 Public DomainPeople with a higher cumulative estrogen exposure throughout their life may have a lower risk of cerebral small vessel disease, ac

Updated on: January 19,2024

Is a longer reproductive lifespan good for your brain?

byAmerican Academy of NeurologyCredit: Pixabay/CC0 Public DomainPeople with a higher cumulative estrogen exposure throughout their life may have a lower risk of cerebral small vessel disease, ac

Updated on:January 19,2024

Hormone protects against development of fatty liver

by Medical University of ViennaGraphical abstract. Credit:Cell Metabolism(2022). DOI: 10.1016/j.cmet.2022.09.020A group at MedUni Vienna has identified a regulatory loop controlled by

Updated on: February 03,2024

Hormone protects against development of fatty liver

by Medical University of ViennaGraphical abstract. Credit:Cell Metabolism(2022). DOI: 10.1016/j.cmet.2022.09.020A group at MedUni Vienna has identified a regulatory loop controlled by

Updated on:February 03,2024

Mice without a functional internal clock have inflexible breathing

by American Physiological SocietyGraphical Abstract. Credit:Function(2023). DOI: 10.1093/function/zqad023New research suggests that the molecular clock, derived from time-keeping gene

Updated on: February 05,2024

Mice without a functional internal clock have inflexible breathing

by American Physiological SocietyGraphical Abstract. Credit:Function(2023). DOI: 10.1093/function/zqad023New research suggests that the molecular clock, derived from time-keeping gene

Updated on:February 05,2024