Implanted cells triggered by electricity used to drive in vivo gene expression

by Justin Jackson , Medical XpressDesign of the direct-current-activated transgene expression switch in mammalian cells.a, Schematic illustration of the stimulation setup for monolayer cultures.

Updated on: January 24,2024

Implanted cells triggered by electricity used to drive in vivo gene expression

by Justin Jackson , Medical XpressDesign of the direct-current-activated transgene expression switch in mammalian cells.a, Schematic illustration of the stimulation setup for monolayer cultures.

Updated on:January 24,2024

YBX1 as a key regulator of mitochondrial pyruvate uptake

by Frontiers JournalsYBX1 resides in the mitochondrial IMS. (a) Representative images of colocalization of YBX1 and PDHA1 in MDA-MB-231, MHCC-97H, and HEK293T cells. Red indicates YBX1 and green indic

Updated on: January 18,2024

YBX1 as a key regulator of mitochondrial pyruvate uptake

by Frontiers JournalsYBX1 resides in the mitochondrial IMS. (a) Representative images of colocalization of YBX1 and PDHA1 in MDA-MB-231, MHCC-97H, and HEK293T cells. Red indicates YBX1 and green indic

Updated on:January 18,2024

Metabolic remodeling during early mouse embryo development

by Zhejiang UniversityCredit: CC0 Public DomainA research team led by Prof. Zhang Jin from the Zhejiang University School of Medicine and the team led by Dr. Hu Zeping from the Tsinghua University Sch

Updated on: February 21,2024

Metabolic remodeling during early mouse embryo development

by Zhejiang UniversityCredit: CC0 Public DomainA research team led by Prof. Zhang Jin from the Zhejiang University School of Medicine and the team led by Dr. Hu Zeping from the Tsinghua University Sch

Updated on:February 21,2024

Potential new targets identified in advanced non-alcoholic fatty liver disease

by The Mount Sinai HospitalHepatic stellate cells along with their intricate cellular projections (green) are shown wrapped around blood vessels (gray) in the healthy liver. Credit: Wang, et al.,

Updated on: February 03,2024

Potential new targets identified in advanced non-alcoholic fatty liver disease

by The Mount Sinai HospitalHepatic stellate cells along with their intricate cellular projections (green) are shown wrapped around blood vessels (gray) in the healthy liver. Credit: Wang, et al.,

Updated on:February 03,2024

Single 'smart' insulin injection regulates glucose levels in mice and minipigs up to one week

by Bob Yirka , Medical XpressDually glucose-responsive complex for insulin delivery. Schematic of complex formation and insulin release with dual glucose-responsive mechanisms. The negatively charged

Updated on: March 14,2024

Single 'smart' insulin injection regulates glucose levels in mice and minipigs up to one week

by Bob Yirka , Medical XpressDually glucose-responsive complex for insulin delivery. Schematic of complex formation and insulin release with dual glucose-responsive mechanisms. The negatively charged

Updated on:March 14,2024

Scientists turn white fat cells into calorie-burning beige fat

byUniversity of California, San FranciscoCredit: Pixabay/CC0 Public DomainA new study shows that suppressing a protein turns ordinary fat into a calorie burner and may explain why drug trials at

Updated on: July 08,2024

Scientists turn white fat cells into calorie-burning beige fat

byUniversity of California, San FranciscoCredit: Pixabay/CC0 Public DomainA new study shows that suppressing a protein turns ordinary fat into a calorie burner and may explain why drug trials at

Updated on:July 08,2024

Healthy eating and activity reverse aging marker in kids with obesity, study finds

by Erin Digitale,Stanford University Medical CenterCredit: Pixabay/CC0 Public DomainA genetic marker linked to premature aging was reversed in children with obesity during a six-month diet and e

Updated on: March 13,2024

Healthy eating and activity reverse aging marker in kids with obesity, study finds

by Erin Digitale,Stanford University Medical CenterCredit: Pixabay/CC0 Public DomainA genetic marker linked to premature aging was reversed in children with obesity during a six-month diet and e

Updated on:March 13,2024

How the ACE2 protein is critical in the damage done to the insulin-producing cells of the pancreas

byDiabetologiaThe detailed mechanism of how SARS-CoV-2 attacks the insulin-producing cells of the pancreas by targeting the angiotensin converting enzyme 2 (ACE2) protein on the surface of those

Updated on: January 27,2024

How the ACE2 protein is critical in the damage done to the insulin-producing cells of the pancreas

byDiabetologiaThe detailed mechanism of how SARS-CoV-2 attacks the insulin-producing cells of the pancreas by targeting the angiotensin converting enzyme 2 (ACE2) protein on the surface of those

Updated on:January 27,2024

Mom's dietary fat rewires male and female brains differently

by Duke UniversityA microglia (in magenta) from a male mouse born to a mom on a high-fat diet, which sequesters more brain serotonin (in green) than males with mom’s eating a typical lab diet. Th

Updated on: February 21,2024

Mom's dietary fat rewires male and female brains differently

by Duke UniversityA microglia (in magenta) from a male mouse born to a mom on a high-fat diet, which sequesters more brain serotonin (in green) than males with mom’s eating a typical lab diet. Th

Updated on:February 21,2024

Wearable monitor detects stress hormone levels across a full 24-hour day

byUniversity of BirminghamThe U-RHYTHM device is worn in a comfortable band placed around the hips. The position of the microdialysis membrane, which is placed superficially in the skin. Credit:

Updated on: January 24,2024

Wearable monitor detects stress hormone levels across a full 24-hour day

byUniversity of BirminghamThe U-RHYTHM device is worn in a comfortable band placed around the hips. The position of the microdialysis membrane, which is placed superficially in the skin. Credit:

Updated on:January 24,2024

Is a longer reproductive lifespan good for your brain?

byAmerican Academy of NeurologyCredit: Pixabay/CC0 Public DomainPeople with a higher cumulative estrogen exposure throughout their life may have a lower risk of cerebral small vessel disease, ac

Updated on: January 19,2024

Is a longer reproductive lifespan good for your brain?

byAmerican Academy of NeurologyCredit: Pixabay/CC0 Public DomainPeople with a higher cumulative estrogen exposure throughout their life may have a lower risk of cerebral small vessel disease, ac

Updated on:January 19,2024

The neonatal ketone body is important for primordial follicle pool formation and regulates ovarian aging in mice

by Higher Education PressThe working model for the function of ketone bodies in formation of primordial follicle pool. Credit: Xin-Ying Wang et alPremature ovarian aging (POA) refers to an early decli

Updated on: February 21,2024

The neonatal ketone body is important for primordial follicle pool formation and regulates ovarian aging in mice

by Higher Education PressThe working model for the function of ketone bodies in formation of primordial follicle pool. Credit: Xin-Ying Wang et alPremature ovarian aging (POA) refers to an early decli

Updated on:February 21,2024