Weight loss of up to 13% achieved in three months with once-a-day tablet, Phase I trial finds

byDiabetologiaCredit: Unsplash/CC0 Public DomainIndividuals who received a once-a-day oral weight loss drug lost up to 13% of their body weight over three months, according to a presentation at

Updated on: September 23,2024

Weight loss of up to 13% achieved in three months with once-a-day tablet, Phase I trial finds

byDiabetologiaCredit: Unsplash/CC0 Public DomainIndividuals who received a once-a-day oral weight loss drug lost up to 13% of their body weight over three months, according to a presentation at

Updated on:September 23,2024

Parathyroidectomy no better for mild primary hyperparathyroidism

For patients with mild primary hyperparathyroidism (PHPT), outcomes at 10 years do not differ for parathyroidectomy (PTX) compared with observation without intervention (OBS), according to a study pub

Updated on: February 03,2024

Parathyroidectomy no better for mild primary hyperparathyroidism

For patients with mild primary hyperparathyroidism (PHPT), outcomes at 10 years do not differ for parathyroidectomy (PTX) compared with observation without intervention (OBS), according to a study pub

Updated on:February 03,2024

Acetate controls endothelial-to-mesenchymal transition: Potential therapeutic target for reducing atherosclerosis

by Yale School of MedicineGraphical abstract. Credit:Cell Metabolism(2023). DOI: 10.1016/j.cmet.2023.05.010In a new study, researchers including Yale School of Medicine's Michael Simon

Updated on: January 24,2024

Acetate controls endothelial-to-mesenchymal transition: Potential therapeutic target for reducing atherosclerosis

by Yale School of MedicineGraphical abstract. Credit:Cell Metabolism(2023). DOI: 10.1016/j.cmet.2023.05.010In a new study, researchers including Yale School of Medicine's Michael Simon

Updated on:January 24,2024

Systematic study of free fatty acids reveals new roles in metabolic diseases

by Stephanie McPherson,Broad Institute of MIT and HarvardHuman pancreatic beta cells show increased membrane rigidity (indicated in red) when exposed to erucic acid, a toxic monounsaturated fatt

Updated on: January 31,2024

Systematic study of free fatty acids reveals new roles in metabolic diseases

by Stephanie McPherson,Broad Institute of MIT and HarvardHuman pancreatic beta cells show increased membrane rigidity (indicated in red) when exposed to erucic acid, a toxic monounsaturated fatt

Updated on:January 31,2024

PPARγ acetylation in macrophages impairs adipose tissue function

by Higher Education PressThe role of macrophage PPARγ acetylation in determining adipose tissue remodeling. Credit: Nicole Aaron, Tarik Zahr, Ying He, Lexiang Yu, Brent Mayfield, Utpal B Pajvani, Li Q

Updated on: February 05,2024

PPARγ acetylation in macrophages impairs adipose tissue function

by Higher Education PressThe role of macrophage PPARγ acetylation in determining adipose tissue remodeling. Credit: Nicole Aaron, Tarik Zahr, Ying He, Lexiang Yu, Brent Mayfield, Utpal B Pajvani, Li Q

Updated on:February 05,2024

Chitin from crustaceans, insects, mushrooms engages the immune system during digestion

byWashington University School of MedicineCredit: Unsplash/CC0 Public DomainWho can forget the stomach-churning moments when "Survivor" contestants forced down crunchy insects, among o

Updated on: January 17,2024

Chitin from crustaceans, insects, mushrooms engages the immune system during digestion

byWashington University School of MedicineCredit: Unsplash/CC0 Public DomainWho can forget the stomach-churning moments when "Survivor" contestants forced down crunchy insects, among o

Updated on:January 17,2024

A unique patient case inspires research in lipodystrophy syndromes

byUniversity of MichiganMallory and Oral at a recent visit. Photo courtesy of Oral. Credit: OralMallory Mattison is a film student at Western Michigan University, studying in hopes of someday be

Updated on: January 17,2024

A unique patient case inspires research in lipodystrophy syndromes

byUniversity of MichiganMallory and Oral at a recent visit. Photo courtesy of Oral. Credit: OralMallory Mattison is a film student at Western Michigan University, studying in hopes of someday be

Updated on:January 17,2024

Research links single gene to female infertility

byHudson Institute of Medical ResearchLoss of Fgfr2c from the ovary leads to an absence in primordial germ cells (PGCs), the precursors of the eggs. Immunofluorescence analysis for the germ cell

Updated on: January 17,2024

Research links single gene to female infertility

byHudson Institute of Medical ResearchLoss of Fgfr2c from the ovary leads to an absence in primordial germ cells (PGCs), the precursors of the eggs. Immunofluorescence analysis for the germ cell

Updated on:January 17,2024

Scientists discover arginine drives metabolic reprogramming to promote tumor growth in liver cancer

byUniversity of BaselTumor organoids (green/blue) are used as a model to study the metabolic changes in liver cell cancer. Credit: Dr. Sandro Nuciforo, Department of Biomedicine, University of B

Updated on: January 18,2024

Scientists discover arginine drives metabolic reprogramming to promote tumor growth in liver cancer

byUniversity of BaselTumor organoids (green/blue) are used as a model to study the metabolic changes in liver cell cancer. Credit: Dr. Sandro Nuciforo, Department of Biomedicine, University of B

Updated on:January 18,2024

Metformin cuts insulin resistance and chances of kidney disease in young, obese rats

byAmerican Physiological SocietyAbstract. Credit:American Journal of Physiology-Renal Physiology(2023). DOI: 10.1152/ajprenal.00078.2023Improving insulin resistance with metformin, a

Updated on: January 18,2024

Metformin cuts insulin resistance and chances of kidney disease in young, obese rats

byAmerican Physiological SocietyAbstract. Credit:American Journal of Physiology-Renal Physiology(2023). DOI: 10.1152/ajprenal.00078.2023Improving insulin resistance with metformin, a

Updated on:January 18,2024

Study shows obese flies live longer on a diet at any age

byUniversity of ConnecticutDrosophila. Credit: WikipediaOld, obese flies get healthier and live longer if put on a diet, University of Connecticut researchers reporton Dec. 8 inPNAS.

Updated on: January 17,2024

Study shows obese flies live longer on a diet at any age

byUniversity of ConnecticutDrosophila. Credit: WikipediaOld, obese flies get healthier and live longer if put on a diet, University of Connecticut researchers reporton Dec. 8 inPNAS.

Updated on:January 17,2024

Synergistic effect of a traditional Chinese medicinal compound on existing diabetes drug found

by Justin Jackson , Medical XpressDiscovery and inhibition of a gut microbial–host isozyme to regulate host metabolism. Differences in the gut microbiota may explain why some individuals respond to an

Updated on: January 24,2024

Synergistic effect of a traditional Chinese medicinal compound on existing diabetes drug found

by Justin Jackson , Medical XpressDiscovery and inhibition of a gut microbial–host isozyme to regulate host metabolism. Differences in the gut microbiota may explain why some individuals respond to an

Updated on:January 24,2024