Study unveils role of mitochondria in dietary fat processing

byUniversity of ColognePictures show small intestinal villi from wild type (top) and enterocyte-specific DARS2 knockout mice (bottom) stained for PLIN2 (yellow), TGN38 (red), E-cadherin (green)

Updated on: January 19,2024

Study unveils role of mitochondria in dietary fat processing

byUniversity of ColognePictures show small intestinal villi from wild type (top) and enterocyte-specific DARS2 knockout mice (bottom) stained for PLIN2 (yellow), TGN38 (red), E-cadherin (green)

Updated on:January 19,2024

Uncovering the role of ATP in ovulation suggests new treatment for infertility

by Nagoya UniversityPurinergic neurons, a source of ATP triggering ovulation. Credit: Naoko Inoue and Hazim Safiullar, Graduate School of Bioagricultural Sciences, Nagoya UniversityA research gro

Updated on: February 03,2024

Uncovering the role of ATP in ovulation suggests new treatment for infertility

by Nagoya UniversityPurinergic neurons, a source of ATP triggering ovulation. Credit: Naoko Inoue and Hazim Safiullar, Graduate School of Bioagricultural Sciences, Nagoya UniversityA research gro

Updated on:February 03,2024

PPARγ acetylation in macrophages impairs adipose tissue function

by Higher Education PressThe role of macrophage PPARγ acetylation in determining adipose tissue remodeling. Credit: Nicole Aaron, Tarik Zahr, Ying He, Lexiang Yu, Brent Mayfield, Utpal B Pajvani, Li Q

Updated on: February 05,2024

PPARγ acetylation in macrophages impairs adipose tissue function

by Higher Education PressThe role of macrophage PPARγ acetylation in determining adipose tissue remodeling. Credit: Nicole Aaron, Tarik Zahr, Ying He, Lexiang Yu, Brent Mayfield, Utpal B Pajvani, Li Q

Updated on:February 05,2024

COVID-19 vaccination appears to be safe for patients treated for hypothyroidism

byThe Endocrine SocietyCredit: Pixabay/CC0 Public DomainInactivated and mRNA COVID-19 vaccines appear to be safe for patients treated for hypothyroidism, according to a new study being presented

Updated on: January 27,2024

COVID-19 vaccination appears to be safe for patients treated for hypothyroidism

byThe Endocrine SocietyCredit: Pixabay/CC0 Public DomainInactivated and mRNA COVID-19 vaccines appear to be safe for patients treated for hypothyroidism, according to a new study being presented

Updated on:January 27,2024

Obesity disrupts normal liver function in mice, study finds

by University of TokyoThe omics included in this study were transcriptome (mRNAs), proteome (proteins), metabolome (metabolites), lipidome (lipids), phosphoproteomes and insulin-signaling molecul

Updated on: March 08,2024

Obesity disrupts normal liver function in mice, study finds

by University of TokyoThe omics included in this study were transcriptome (mRNAs), proteome (proteins), metabolome (metabolites), lipidome (lipids), phosphoproteomes and insulin-signaling molecul

Updated on:March 08,2024

Scientists gain ground on rare congenital neurological disorder

by Cedars-Sinai Medical CenterCredit: Unsplash/CC0 Public DomainTwo recent discoveries co-led by scientists at Cedars-Sinai may help lead to new ways to treat patients withAllan-Herndon-Dud

Updated on: February 05,2024

Scientists gain ground on rare congenital neurological disorder

by Cedars-Sinai Medical CenterCredit: Unsplash/CC0 Public DomainTwo recent discoveries co-led by scientists at Cedars-Sinai may help lead to new ways to treat patients withAllan-Herndon-Dud

Updated on:February 05,2024

Western high-fat diet can cause chronic pain, according to research team

by University of Texas Health Science Center at San AntonioCredit: CC0 Public DomainA typical Western high-fat diet can increase the risk of painful disorders common in people with conditions suc

Updated on: February 21,2024

Western high-fat diet can cause chronic pain, according to research team

by University of Texas Health Science Center at San AntonioCredit: CC0 Public DomainA typical Western high-fat diet can increase the risk of painful disorders common in people with conditions suc

Updated on:February 21,2024

Anxiodepressive disorders: Much more than a matter of weight

by University of Montreal Hospital Research Centre (CRCHUM)Credit: CC0 Public DomainObese people run a higher-than-average risk of depression or anxiety, the result of a combination of factors: poor d

Updated on: February 05,2024

Anxiodepressive disorders: Much more than a matter of weight

by University of Montreal Hospital Research Centre (CRCHUM)Credit: CC0 Public DomainObese people run a higher-than-average risk of depression or anxiety, the result of a combination of factors: poor d

Updated on:February 05,2024

Metformin cuts insulin resistance and chances of kidney disease in young, obese rats

byAmerican Physiological SocietyAbstract. Credit:American Journal of Physiology-Renal Physiology(2023). DOI: 10.1152/ajprenal.00078.2023Improving insulin resistance with metformin, a

Updated on: January 18,2024

Metformin cuts insulin resistance and chances of kidney disease in young, obese rats

byAmerican Physiological SocietyAbstract. Credit:American Journal of Physiology-Renal Physiology(2023). DOI: 10.1152/ajprenal.00078.2023Improving insulin resistance with metformin, a

Updated on:January 18,2024

Gut-derived exosomes as a novel mediator of hepatic lipid metabolism

by Frontiers JournalsScientific hypothesis: intestinal epithelium-derived exosomes regulate hepatic metabolic activities by carrying substances such as microRNA. Credit:Life Metabolism(202

Updated on: January 19,2024

Gut-derived exosomes as a novel mediator of hepatic lipid metabolism

by Frontiers JournalsScientific hypothesis: intestinal epithelium-derived exosomes regulate hepatic metabolic activities by carrying substances such as microRNA. Credit:Life Metabolism(202

Updated on:January 19,2024

Single 'smart' insulin injection regulates glucose levels in mice and minipigs up to one week

by Bob Yirka , Medical XpressDually glucose-responsive complex for insulin delivery. Schematic of complex formation and insulin release with dual glucose-responsive mechanisms. The negatively charged

Updated on: March 14,2024

Single 'smart' insulin injection regulates glucose levels in mice and minipigs up to one week

by Bob Yirka , Medical XpressDually glucose-responsive complex for insulin delivery. Schematic of complex formation and insulin release with dual glucose-responsive mechanisms. The negatively charged

Updated on:March 14,2024

The human lipidome reveals new indicators of health, disease and aging

byStanford University Medical CenterLipid–cytokine associations.a–e, Network of 1,245 significant (BH FDR < 5%) lipid–cytokine associations, indicating positive (red) and negative (blue

Updated on: January 19,2024

The human lipidome reveals new indicators of health, disease and aging

byStanford University Medical CenterLipid–cytokine associations.a–e, Network of 1,245 significant (BH FDR < 5%) lipid–cytokine associations, indicating positive (red) and negative (blue

Updated on:January 19,2024