Researchers investigate the multi-omic landscape of steatosis-to-NASH progression in mice

by Higher Education PressPlasma GDF3 levels are significantly associated with histologic features in patients with NASH. Credit:Life Metabolism(2022). DOI: 10.1093/lifemeta/loac034The glob

Updated on: February 19,2024

Researchers investigate the multi-omic landscape of steatosis-to-NASH progression in mice

by Higher Education PressPlasma GDF3 levels are significantly associated with histologic features in patients with NASH. Credit:Life Metabolism(2022). DOI: 10.1093/lifemeta/loac034The glob

Updated on:February 19,2024

New cause identified for metabolic disease that strikes Native Americans

by Duke University Medical CenterCredit: Shawn Rocco/Duke HealthDuke Health researchers have identified the cause of an inherited metabolic disease common among people with Lumbee and other Nativ

Updated on: January 31,2024

New cause identified for metabolic disease that strikes Native Americans

by Duke University Medical CenterCredit: Shawn Rocco/Duke HealthDuke Health researchers have identified the cause of an inherited metabolic disease common among people with Lumbee and other Nativ

Updated on:January 31,2024

Obesity disrupts normal liver function in mice, study finds

by University of TokyoThe omics included in this study were transcriptome (mRNAs), proteome (proteins), metabolome (metabolites), lipidome (lipids), phosphoproteomes and insulin-signaling molecul

Updated on: March 08,2024

Obesity disrupts normal liver function in mice, study finds

by University of TokyoThe omics included in this study were transcriptome (mRNAs), proteome (proteins), metabolome (metabolites), lipidome (lipids), phosphoproteomes and insulin-signaling molecul

Updated on:March 08,2024

Scientists discover that metabolic sensor may play role in Alzheimer's disease

by Atrium Health Wake Forest BaptistCredit:JCI Insight(2023). DOI: 10.1172/jci.insight.162454It's well-known that people with type 2 diabetes are at an increased risk of developing Alz

Updated on: February 03,2024

Scientists discover that metabolic sensor may play role in Alzheimer's disease

by Atrium Health Wake Forest BaptistCredit:JCI Insight(2023). DOI: 10.1172/jci.insight.162454It's well-known that people with type 2 diabetes are at an increased risk of developing Alz

Updated on:February 03,2024

Expression of p-STAT3 and c-Myc correlates with P2-HNF4α expression in nonalcoholic fatty liver disease (NAFLD)

by Impact Journals LLCExamples of positive nuclear expression of (A) P1-HNF4α; (B) P2-HNF4α; (C) p-STAT3 and (D) c-Myc and human liver biopsies with non-alcoholic fatty liver disease (NAFLD). 20X micr

Updated on: February 03,2024

Expression of p-STAT3 and c-Myc correlates with P2-HNF4α expression in nonalcoholic fatty liver disease (NAFLD)

by Impact Journals LLCExamples of positive nuclear expression of (A) P1-HNF4α; (B) P2-HNF4α; (C) p-STAT3 and (D) c-Myc and human liver biopsies with non-alcoholic fatty liver disease (NAFLD). 20X micr

Updated on:February 03,2024

Turning down the hormone dial could improve IVF live birth rates

by Emilie Lorditch,Michigan State UniversityCredit: Pixabay/CC0 Public DomainIn a first-of-its-kind study, researchers at Michigan State University are studying ovarian stimulation protocols in

Updated on: February 05,2024

Turning down the hormone dial could improve IVF live birth rates

by Emilie Lorditch,Michigan State UniversityCredit: Pixabay/CC0 Public DomainIn a first-of-its-kind study, researchers at Michigan State University are studying ovarian stimulation protocols in

Updated on:February 05,2024

Are midlife women doomed to gain weight?

by The North American Menopause SocietyCredit: Pixabay/CC0 Public DomainWeight gain is a common complaint of midlife women, with more than two-thirds of midlife US women being over the ideal weig

Updated on: February 21,2024

Are midlife women doomed to gain weight?

by The North American Menopause SocietyCredit: Pixabay/CC0 Public DomainWeight gain is a common complaint of midlife women, with more than two-thirds of midlife US women being over the ideal weig

Updated on:February 21,2024

Iron accumulation: A new insight into fibrotic diseases

byInstitute for Research in Biomedicine (IRB Barcelona)Iron accumulation: a new insight into fibrotic diseases. Credit: IRB BarcelonaFibrosis is associated with various chronic and life-threaten

Updated on: January 20,2024

Iron accumulation: A new insight into fibrotic diseases

byInstitute for Research in Biomedicine (IRB Barcelona)Iron accumulation: a new insight into fibrotic diseases. Credit: IRB BarcelonaFibrosis is associated with various chronic and life-threaten

Updated on:January 20,2024

Metformin cuts insulin resistance and chances of kidney disease in young, obese rats

byAmerican Physiological SocietyAbstract. Credit:American Journal of Physiology-Renal Physiology(2023). DOI: 10.1152/ajprenal.00078.2023Improving insulin resistance with metformin, a

Updated on: January 18,2024

Metformin cuts insulin resistance and chances of kidney disease in young, obese rats

byAmerican Physiological SocietyAbstract. Credit:American Journal of Physiology-Renal Physiology(2023). DOI: 10.1152/ajprenal.00078.2023Improving insulin resistance with metformin, a

Updated on:January 18,2024

Scientists discover a new understanding of how an old hormone works, paving way for better therapies

byMonash UniversityCredit:Nature Communications(2024). DOI: 10.1038/s41467-024-52703-wMonash University researchers have discovered how the hormone peptide glucagon could better trea

Updated on: October 22,2024

Scientists discover a new understanding of how an old hormone works, paving way for better therapies

byMonash UniversityCredit:Nature Communications(2024). DOI: 10.1038/s41467-024-52703-wMonash University researchers have discovered how the hormone peptide glucagon could better trea

Updated on:October 22,2024

Diabetes: When circadian lipid rhythms go wrong

byUniversity of GenevaHuman pancreatic islet cells with compromised clocks bear decreased membrane lipid fluidity, as compared to the islet cells with functional clocks © 2022. Petrenko et al. (

Updated on: February 19,2024

Diabetes: When circadian lipid rhythms go wrong

byUniversity of GenevaHuman pancreatic islet cells with compromised clocks bear decreased membrane lipid fluidity, as compared to the islet cells with functional clocks © 2022. Petrenko et al. (

Updated on:February 19,2024

Reprogramming of energy metabolism restores cardiac function after infarction in mice

byMax Planck SocietyIn mice with an inactive Cpt1b gene, the heart can regenerate after an infarction. Credit: MPI for Heart and Lung Research, created with Biorender.comAfter birth, the human h

Updated on: January 17,2024

Reprogramming of energy metabolism restores cardiac function after infarction in mice

byMax Planck SocietyIn mice with an inactive Cpt1b gene, the heart can regenerate after an infarction. Credit: MPI for Heart and Lung Research, created with Biorender.comAfter birth, the human h

Updated on:January 17,2024