Shifting focus: Investigators describe changes to pancreatic β cells at onset of type 1 diabetes

by Joslin Diabetes CenterIn vivo AAV8-mediated overexpression of Mettl3 in NOD mouse β-cells delays T1D progression. Credit:Nature Cell Biology(2024). DOI: 10.1038/s41556-024-01368-0A

Updated on: March 14,2024

Shifting focus: Investigators describe changes to pancreatic β cells at onset of type 1 diabetes

by Joslin Diabetes CenterIn vivo AAV8-mediated overexpression of Mettl3 in NOD mouse β-cells delays T1D progression. Credit:Nature Cell Biology(2024). DOI: 10.1038/s41556-024-01368-0A

Updated on:March 14,2024

New study links high birth weight to childhood obesity in the US

by TranSpreadCredit: Pixabay/CC0 Public DomainA new studypublishedin the journalReproductive and Developmental Medicinehas found a strong association between fetal macrosomia (

Updated on: March 13,2024

New study links high birth weight to childhood obesity in the US

by TranSpreadCredit: Pixabay/CC0 Public DomainA new studypublishedin the journalReproductive and Developmental Medicinehas found a strong association between fetal macrosomia (

Updated on:March 13,2024

'Diabetes distress' can increase risk of mental health problems among young people living with type 1 diabetes

byUniversity of CambridgeCredit: CC0 Public DomainChildren diagnosed with type 1 diabetes are at significantly higher risk of a number of mental health issues, including mood and anxiety disorde

Updated on: July 30,2024

'Diabetes distress' can increase risk of mental health problems among young people living with type 1 diabetes

byUniversity of CambridgeCredit: CC0 Public DomainChildren diagnosed with type 1 diabetes are at significantly higher risk of a number of mental health issues, including mood and anxiety disorde

Updated on:July 30,2024

Scientists demonstrate a combination treatment can increase human insulin-producing cells in vivo

byThe Mount Sinai HospitalCredit: CC0 Public DomainIn preclinical studies, a team of researchers from Mount Sinai Health System in New York City and City of Hope in Los Angeles report new findin

Updated on: July 17,2024

Scientists demonstrate a combination treatment can increase human insulin-producing cells in vivo

byThe Mount Sinai HospitalCredit: CC0 Public DomainIn preclinical studies, a team of researchers from Mount Sinai Health System in New York City and City of Hope in Los Angeles report new findin

Updated on:July 17,2024

Hormone therapy for gender dysphoria may raise cardiovascular risks

by American College of CardiologyCredit: Pixabay/CC0 Public DomainPeople with gender dysphoria taking hormone replacements as part of gender affirmation therapy face a substantially increased ris

Updated on: February 21,2024

Hormone therapy for gender dysphoria may raise cardiovascular risks

by American College of CardiologyCredit: Pixabay/CC0 Public DomainPeople with gender dysphoria taking hormone replacements as part of gender affirmation therapy face a substantially increased ris

Updated on:February 21,2024

Abnormal lactate metabolism linked to kidney injury in diabetic patients

by Federico Graciano,Duke-NUS Medical SchoolCredit: Pixabay/CC0 Public DomainDisrupted kidney metabolism is a key driver of progressive kidney injury in diabetic kidney disease (DKD), according

Updated on: January 17,2024

Abnormal lactate metabolism linked to kidney injury in diabetic patients

by Federico Graciano,Duke-NUS Medical SchoolCredit: Pixabay/CC0 Public DomainDisrupted kidney metabolism is a key driver of progressive kidney injury in diabetic kidney disease (DKD), according

Updated on:January 17,2024

Food companies' sponsorship of children's sports encourages children to buy their products, Canadian research suggests

by European Association for the Study of ObesityCredit: CC0 Public DomainResearch to be presented at theEuropean Congress on Obesity(ECO 2024) held in Venice 12–15 May, has found that food

Updated on: March 27,2024

Food companies' sponsorship of children's sports encourages children to buy their products, Canadian research suggests

by European Association for the Study of ObesityCredit: CC0 Public DomainResearch to be presented at theEuropean Congress on Obesity(ECO 2024) held in Venice 12–15 May, has found that food

Updated on:March 27,2024

Metformin may lower dementia risk in black patients with T2DM

(HealthDay)—Metformin use is associated with a substantially lower risk for dementia among younger African-American patients with diabetes compared with sulfonylurea initiation, according to a study p

Updated on: May 28,2024

Metformin may lower dementia risk in black patients with T2DM

(HealthDay)—Metformin use is associated with a substantially lower risk for dementia among younger African-American patients with diabetes compared with sulfonylurea initiation, according to a study p

Updated on:May 28,2024

Researchers find cold-activated brown fat asks for more sugar via signaling RNAkines

by Nanjing University School of Life SciencesBAT stimulates hepatic gluconeogenesis upon cold exposure.a–jEight-week-old male C57BL6/J mice were placed in RT (25 °C) or cold (4 °C) for 72 

Updated on: January 19,2024

Researchers find cold-activated brown fat asks for more sugar via signaling RNAkines

by Nanjing University School of Life SciencesBAT stimulates hepatic gluconeogenesis upon cold exposure.a–jEight-week-old male C57BL6/J mice were placed in RT (25 °C) or cold (4 °C) for 72 

Updated on:January 19,2024

Worrying regional disparities found in lower limb amputation caused by arterial disease

by University of SheffieldPopulation-based AKA and BKA rates by age, sex and diabetes status; England (April 2006 to March 2018) AKA, above knee amputation; BKA, below knee amputation. Credit:&nb

Updated on: March 27,2024

Worrying regional disparities found in lower limb amputation caused by arterial disease

by University of SheffieldPopulation-based AKA and BKA rates by age, sex and diabetes status; England (April 2006 to March 2018) AKA, above knee amputation; BKA, below knee amputation. Credit:&nb

Updated on:March 27,2024

What makes mice fat, but not rats? Suppressing NMU, study finds

by Okayama UniversityAccording to a new study conducted by Okayama University researchers, the species-specific expression pattern of the NMU gene was responsible for different functions in rats

Updated on: February 21,2024

What makes mice fat, but not rats? Suppressing NMU, study finds

by Okayama UniversityAccording to a new study conducted by Okayama University researchers, the species-specific expression pattern of the NMU gene was responsible for different functions in rats

Updated on:February 21,2024

Risk prediction using genes and gut bacteria can improve early detection of diseases like type 2 diabetes

by Tracey Ellis,University of CambridgeCross-validated Ridge logistic regression models for incident (a) CAD, (b) T2D, (c) AD and (d) prostate cancer using gut microbiome composition. The ROC cu

Updated on: March 27,2024

Risk prediction using genes and gut bacteria can improve early detection of diseases like type 2 diabetes

by Tracey Ellis,University of CambridgeCross-validated Ridge logistic regression models for incident (a) CAD, (b) T2D, (c) AD and (d) prostate cancer using gut microbiome composition. The ROC cu

Updated on:March 27,2024