Diabetes & Endocrinology

Shifting focus: Investigators describe changes to pancreatic β cells at onset of type 1 diabetes

by Joslin Diabetes CenterIn vivo AAV8-mediated overexpression of Mettl3 in NOD mouse β-cells delays T1D progression. Credit:Nature Cell Biology(2024). DOI: 10.1038/s41556-024-01368-0A

Updated on: March 14,2024

Shifting focus: Investigators describe changes to pancreatic β cells at onset of type 1 diabetes

by Joslin Diabetes CenterIn vivo AAV8-mediated overexpression of Mettl3 in NOD mouse β-cells delays T1D progression. Credit:Nature Cell Biology(2024). DOI: 10.1038/s41556-024-01368-0A

Updated on:March 14,2024

Higher blood fats more harmful than first thought

by University of LeedsMicroscopy image showing human muscle cells with nuclei in blue, and stress caused by the ceramide stress signals shown in red. Credit: Lee RobertsIncreased levels of blood

Updated on: January 31,2024

Higher blood fats more harmful than first thought

by University of LeedsMicroscopy image showing human muscle cells with nuclei in blue, and stress caused by the ceramide stress signals shown in red. Credit: Lee RobertsIncreased levels of blood

Updated on:January 31,2024

Expression pattern of key receptors in the hypothalamus revealed

by Susann-C. Ruprecht, Deutsches Institut für Ernährungsforschung Potsdam-RehbrückeBrain slices of the mouse are placed onto a glass slide, for further imaging. Credit: David AusserhoferThere is growi

Updated on: January 17,2024

Expression pattern of key receptors in the hypothalamus revealed

by Susann-C. Ruprecht, Deutsches Institut für Ernährungsforschung Potsdam-RehbrückeBrain slices of the mouse are placed onto a glass slide, for further imaging. Credit: David AusserhoferThere is growi

Updated on:January 17,2024

Experts weigh in on new generation of weight loss medications

by Julie Rafferty,Tufts UniversityCredit: Pixabay/CC0 Public DomainWe've all seen the ads and read about celebrities who have successfully lost weight using one of the new weight loss medica

Updated on: July 10,2024

Experts weigh in on new generation of weight loss medications

by Julie Rafferty,Tufts UniversityCredit: Pixabay/CC0 Public DomainWe've all seen the ads and read about celebrities who have successfully lost weight using one of the new weight loss medica

Updated on:July 10,2024

An overactive sweet tooth may spell trouble for our cellular powerplants

by Van Andel Research InstituteCredit: CC0 Public DomainThe average American eatsroughly 22 teaspoons of added sugar a day—more than three times the recommended amount for women and more th

Updated on: February 05,2024

An overactive sweet tooth may spell trouble for our cellular powerplants

by Van Andel Research InstituteCredit: CC0 Public DomainThe average American eatsroughly 22 teaspoons of added sugar a day—more than three times the recommended amount for women and more th

Updated on:February 05,2024

Diabetes and Liver Cancer: What Is the Relationship?

Diabetes and Liver Cancer: What Is the Relationship?ByJames Myhre & Dennis Sifris, MDPublished on November 17, 2022Medically reviewed byIsabel Casimiro, MD, PhDDiabetes&nbs

Updated on: July 01,2024

Diabetes and Liver Cancer: What Is the Relationship?

Diabetes and Liver Cancer: What Is the Relationship?ByJames Myhre & Dennis Sifris, MDPublished on November 17, 2022Medically reviewed byIsabel Casimiro, MD, PhDDiabetes&nbs

Updated on:July 01,2024

Gulf War Illness significantly reduces white blood cells' ability to make energy, study finds

byDuke UniversityUS Troops in the Persian Gulf War (1991). Gulf War Illness (GWI), which affects approximately 250,000 U.S. veterans, has been found to significantly reduce the ability of white

Updated on: January 09,2024

Gulf War Illness significantly reduces white blood cells' ability to make energy, study finds

byDuke UniversityUS Troops in the Persian Gulf War (1991). Gulf War Illness (GWI), which affects approximately 250,000 U.S. veterans, has been found to significantly reduce the ability of white

Updated on:January 09,2024

Females less likely to heal from ACL injuries than males, finds study

by Sara LaJeunesse,Pennsylvania State UniversityCell viability with ex vivo loading. (A) Representative images in the deep portion of the tissue for each loading condition. Green (FDA) represent

Updated on: January 19,2024

Females less likely to heal from ACL injuries than males, finds study

by Sara LaJeunesse,Pennsylvania State UniversityCell viability with ex vivo loading. (A) Representative images in the deep portion of the tissue for each loading condition. Green (FDA) represent

Updated on:January 19,2024

Study reveals the role of ERRγ in the regulation of FGF23 gene expression following acute liver injury

by TranSpreadCCl4-induced acute liver injury increases FGF23 gene expression and secretion in mouse liver through ERRγ. (A, B) Quantitative PCR analysis of total RNA obtained from the livers of mice i

Updated on: January 18,2024

Study reveals the role of ERRγ in the regulation of FGF23 gene expression following acute liver injury

by TranSpreadCCl4-induced acute liver injury increases FGF23 gene expression and secretion in mouse liver through ERRγ. (A, B) Quantitative PCR analysis of total RNA obtained from the livers of mice i

Updated on:January 18,2024

Mouse study highlights potential therapeutic for one of the major chronic diseases of aging

by Buck Institute for Research on AgingGraphical abstract. Credit:Free Radical Biology and Medicine(2023). DOI: 10.1016/j.freeradbiomed.2023.05.022Mopping up free radicals with antioxidant

Updated on: January 22,2024

Mouse study highlights potential therapeutic for one of the major chronic diseases of aging

by Buck Institute for Research on AgingGraphical abstract. Credit:Free Radical Biology and Medicine(2023). DOI: 10.1016/j.freeradbiomed.2023.05.022Mopping up free radicals with antioxidant

Updated on:January 22,2024

Study shows medial preoptic area mediates depressive-like behaviors associated with ovarian hormone fluctuations

by Ingrid Fadelli , Medical XpressElectrophysiological recording from MPOA GABAergic neurons (Vgat+) demonstrated that these neurons reduced their spiking activity in HW-treated mice compared to non-H