Nucleic acid drug iSN40 shows promise for osteoporosis treatment

byShinshu UniversityIn a new study, researchers from Japan reveal that iSN40 suppresses osteoclast differentiation and bone matrix resorption, offering a potential therapeutic approach for osteo

Updated on: January 18,2025

Nucleic acid drug iSN40 shows promise for osteoporosis treatment

byShinshu UniversityIn a new study, researchers from Japan reveal that iSN40 suppresses osteoclast differentiation and bone matrix resorption, offering a potential therapeutic approach for osteo

Updated on:January 18,2025

Scientists identify rare gene variants which confer up to 6-fold increase in risk of obesity

by UK Research and InnovationCredit: Pixabay/CC0 Public DomainA study led by Medical Research Council (MRC) researchers has identified genetic variants in two genes that have some of the largest

Updated on: April 06,2024

Scientists identify rare gene variants which confer up to 6-fold increase in risk of obesity

by UK Research and InnovationCredit: Pixabay/CC0 Public DomainA study led by Medical Research Council (MRC) researchers has identified genetic variants in two genes that have some of the largest

Updated on:April 06,2024

Drug may counteract muscle loss and osteoporosis after rapid weight loss

Updated on: March 17,2025

Drug may counteract muscle loss and osteoporosis after rapid weight loss

Updated on:March 17,2025

WTAP regulates the postnatal development and thermogenesis of iBAT

by Higher Education PressWorking model for WTAP/METTL3 in the regulation of postnatal development and maturation of BAT. Credit:Life Metabolism(2022). DOI: 10.1093/lifemeta/loac028Obesity

Updated on: January 28,2024

WTAP regulates the postnatal development and thermogenesis of iBAT

by Higher Education PressWorking model for WTAP/METTL3 in the regulation of postnatal development and maturation of BAT. Credit:Life Metabolism(2022). DOI: 10.1093/lifemeta/loac028Obesity

Updated on:January 28,2024

Under-the-skin implant could treat type I diabetes

by David Nutt,Cornell UniversityDesign of the SHEATH system.a, Schematic illustrating the creation of the vascularized subcutaneous site achieved by implantation of a catheter 4–6 weeks be

Updated on: March 14,2024

Under-the-skin implant could treat type I diabetes

by David Nutt,Cornell UniversityDesign of the SHEATH system.a, Schematic illustrating the creation of the vascularized subcutaneous site achieved by implantation of a catheter 4–6 weeks be

Updated on:March 14,2024

Diabetes and Liver Cancer: What Is the Relationship?

Diabetes and Liver Cancer: What Is the Relationship?ByJames Myhre & Dennis Sifris, MDPublished on November 17, 2022Medically reviewed byIsabel Casimiro, MD, PhDDiabetes&nbs

Updated on: July 01,2024

Diabetes and Liver Cancer: What Is the Relationship?

Diabetes and Liver Cancer: What Is the Relationship?ByJames Myhre & Dennis Sifris, MDPublished on November 17, 2022Medically reviewed byIsabel Casimiro, MD, PhDDiabetes&nbs

Updated on:July 01,2024

New data analysis supports hedonic overdrive model in high-fat diet-induced mice

FEBRUARY 27, 2024byThe Obesity SocietyCredit: Pixabay/CC0 Public DomainHigh-fat diets cause obesity in male mice. The underlying mechanism, however, remains controversial. After assessing three

Updated on: March 25,2024

New data analysis supports hedonic overdrive model in high-fat diet-induced mice

FEBRUARY 27, 2024byThe Obesity SocietyCredit: Pixabay/CC0 Public DomainHigh-fat diets cause obesity in male mice. The underlying mechanism, however, remains controversial. After assessing three

Updated on:March 25,2024

Cycle of fasting and feeding is crucial for healthy aging, killifish study suggests

byMax Planck SocietyKillifish age in fast motion. The bright colours of their youth fade after just a few months. Credit: K. Link / Max Planck Institute for Biology of AgeingFasting intervention

Updated on: January 09,2024

Cycle of fasting and feeding is crucial for healthy aging, killifish study suggests

byMax Planck SocietyKillifish age in fast motion. The bright colours of their youth fade after just a few months. Credit: K. Link / Max Planck Institute for Biology of AgeingFasting intervention

Updated on:January 09,2024

Sugar boosts cravings for fat, Drosophila study finds

by Sara-Lena Brännström,Umea UniversityGraphical abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113387People are eating too much sugar, and research increasingly sug

Updated on: January 09,2024

Sugar boosts cravings for fat, Drosophila study finds

by Sara-Lena Brännström,Umea UniversityGraphical abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113387People are eating too much sugar, and research increasingly sug

Updated on:January 09,2024

Researchers identify protein that increases the formation of good brown fat

by Inka Väth,University Hospital BonnEPAC1 signaling promotes BAT growth and function in vivo. Credit:Nature Cell Biology(2024). DOI: 10.1038/s41556-023-01311-9Brown fat cells conver

Updated on: March 08,2024

Researchers identify protein that increases the formation of good brown fat

by Inka Väth,University Hospital BonnEPAC1 signaling promotes BAT growth and function in vivo. Credit:Nature Cell Biology(2024). DOI: 10.1038/s41556-023-01311-9Brown fat cells conver

Updated on:March 08,2024

Chaperoning fat storage: The molecular basis of adiposity

byOsaka UniversityBody fat levels vary due to physiological, pathological, environmental, hormonal, and genetic factors. Our study identifies HSP47—abundant in fat tissues—as a key determinant o

Updated on: January 09,2024

Chaperoning fat storage: The molecular basis of adiposity

byOsaka UniversityBody fat levels vary due to physiological, pathological, environmental, hormonal, and genetic factors. Our study identifies HSP47—abundant in fat tissues—as a key determinant o

Updated on:January 09,2024

Remote height and weight measurements for children proven as accurate as in-person

by Louisiana State UniversityConfirmed by researchers at Pennington Biomedical, remotely gathered physical measurements to bridge gap for families who may be unable to attend in-person studies or

Updated on: March 13,2024

Remote height and weight measurements for children proven as accurate as in-person

by Louisiana State UniversityConfirmed by researchers at Pennington Biomedical, remotely gathered physical measurements to bridge gap for families who may be unable to attend in-person studies or

Updated on:March 13,2024