Chaperoning fat storage: The molecular basis of adiposity

byOsaka UniversityBody fat levels vary due to physiological, pathological, environmental, hormonal, and genetic factors. Our study identifies HSP47—abundant in fat tissues—as a key determinant o

Updated on: January 09,2024 19

Chaperoning fat storage: The molecular basis of adiposity

byOsaka UniversityBody fat levels vary due to physiological, pathological, environmental, hormonal, and genetic factors. Our study identifies HSP47—abundant in fat tissues—as a key determinant o

Updated on:January 09,2024 19

Females less likely to heal from ACL injuries than males, finds study

by Sara LaJeunesse,Pennsylvania State UniversityCell viability with ex vivo loading. (A) Representative images in the deep portion of the tissue for each loading condition. Green (FDA) represent

Updated on: January 19,2024 15

Females less likely to heal from ACL injuries than males, finds study

by Sara LaJeunesse,Pennsylvania State UniversityCell viability with ex vivo loading. (A) Representative images in the deep portion of the tissue for each loading condition. Green (FDA) represent

Updated on:January 19,2024 15

Excess ceramide and disrupted iron metabolism in neuronal mitochondria found to be the cause for MEPAN syndrome

byTexas Children's HospitalMecr is enriched in a subset of glial cells in the larval brain and is present in mitochondria in salivary glands. a, Schematic diagram showing the mecr-GFP transg

Updated on: January 20,2024 12

Excess ceramide and disrupted iron metabolism in neuronal mitochondria found to be the cause for MEPAN syndrome

byTexas Children's HospitalMecr is enriched in a subset of glial cells in the larval brain and is present in mitochondria in salivary glands. a, Schematic diagram showing the mecr-GFP transg

Updated on:January 20,2024 12

Researchers uncover mechanism for treating dangerous liver condition

by Steve Lundeberg,Oregon State UniversityNASH mouse model outlines all expression/omics data, DHA/EPA treatment effects on outcome. Credit:EMBO Molecular Medicine(2023). DOI: 10.152

Updated on: January 19,2024 10

Researchers uncover mechanism for treating dangerous liver condition

by Steve Lundeberg,Oregon State UniversityNASH mouse model outlines all expression/omics data, DHA/EPA treatment effects on outcome. Credit:EMBO Molecular Medicine(2023). DOI: 10.152

Updated on:January 19,2024 10

Studies help explain why some prostate cancers become resistant to hormone therapy

byUniversity of California, Los AngelesGraphical abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113221Two new studies led by researchers from the UCLA Jonsson Compre

Updated on: January 09,2024 7

Studies help explain why some prostate cancers become resistant to hormone therapy

byUniversity of California, Los AngelesGraphical abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113221Two new studies led by researchers from the UCLA Jonsson Compre

Updated on:January 09,2024 7

Research advances one step closer to stem cell therapy for type 1 diabetes

by Salk InstituteFunctional beta cells made from human pluripotent stem cells. Insulin (red) and NKX6.1 (green) indicate two proteins produced by beta cells. Credit: Salk InstituteType 1 diabetes

Updated on: February 03,2024 24

Research advances one step closer to stem cell therapy for type 1 diabetes

by Salk InstituteFunctional beta cells made from human pluripotent stem cells. Insulin (red) and NKX6.1 (green) indicate two proteins produced by beta cells. Credit: Salk InstituteType 1 diabetes

Updated on:February 03,2024 24

Study finds mice make better distance runners on time-restricted diet

by Justin Jackson , Medical XpressEffects of time-restricted feeding on metabolic and physical fitness. Credit:Nature Metabolism(2023). DOI: 10.1038/s42255-023-00833-8A study led by the De

Updated on: January 22,2024 23

Study finds mice make better distance runners on time-restricted diet

by Justin Jackson , Medical XpressEffects of time-restricted feeding on metabolic and physical fitness. Credit:Nature Metabolism(2023). DOI: 10.1038/s42255-023-00833-8A study led by the De

Updated on:January 22,2024 23

New 'atlas' maps bacteria and metabolites associated with elevated risk of cardiovascular disease

byCleveland ClinicCredit: CC0 Public DomainA Cleveland Clinic research team has published an "atlas" of metabolites associated with cardiovascular disease in theEuropean Heart Jo

Updated on: January 22,2024 18

New 'atlas' maps bacteria and metabolites associated with elevated risk of cardiovascular disease

byCleveland ClinicCredit: CC0 Public DomainA Cleveland Clinic research team has published an "atlas" of metabolites associated with cardiovascular disease in theEuropean Heart Jo

Updated on:January 22,2024 18

Researchers connect diet to changes in the microbiome

by Kara Mason,CU Anschutz Medical CampusCross-sectional associations between DNAme and gut microbiota. The Sankey plot displays associations between gut microbiota and DNAme of CpGs within label

Updated on: January 22,2024 14

Researchers connect diet to changes in the microbiome

by Kara Mason,CU Anschutz Medical CampusCross-sectional associations between DNAme and gut microbiota. The Sankey plot displays associations between gut microbiota and DNAme of CpGs within label

Updated on:January 22,2024 14

Fiber against pounds: Resistant starch found to support weight loss

by Antje Nieber,Friedrich Schiller University of JenaRS intake facilitates weight loss in humans by reshaping the gut microbiota. Credit:Nature Metabolism(2024). DOI: 10.1038/s42255-

Updated on: March 08,2024 15

Fiber against pounds: Resistant starch found to support weight loss

by Antje Nieber,Friedrich Schiller University of JenaRS intake facilitates weight loss in humans by reshaping the gut microbiota. Credit:Nature Metabolism(2024). DOI: 10.1038/s42255-

Updated on:March 08,2024 15

Metformin treatment linked to slowed cognitive decline

by Garvan Institute of Medical ResearchCredit: CC0 Public DomainMetformin is the first-line treatment for most cases of type 2 diabetes and one of the most commonly prescribed medications worldwi

Updated on: May 28,2024 5

Metformin treatment linked to slowed cognitive decline

by Garvan Institute of Medical ResearchCredit: CC0 Public DomainMetformin is the first-line treatment for most cases of type 2 diabetes and one of the most commonly prescribed medications worldwi

Updated on:May 28,2024 5

Eating dark chocolate linked to reduced risk of type 2 diabetes: Clinical trials needed to confirm, say experts

byBritish Medical JournalCredit: CC0 Public DomainEating five servings of dark chocolate a week is associated with a reduction in the risk of type 2 diabetes, according to a long-term US study&n

Updated on: December 11,2024 0

Eating dark chocolate linked to reduced risk of type 2 diabetes: Clinical trials needed to confirm, say experts

byBritish Medical JournalCredit: CC0 Public DomainEating five servings of dark chocolate a week is associated with a reduction in the risk of type 2 diabetes, according to a long-term US study&n

Updated on:December 11,2024 0