Shifting focus: Investigators describe changes to pancreatic β cells at onset of type 1 diabetes

by Joslin Diabetes CenterIn vivo AAV8-mediated overexpression of Mettl3 in NOD mouse β-cells delays T1D progression. Credit:Nature Cell Biology(2024). DOI: 10.1038/s41556-024-01368-0A

Updated on: March 14,2024

Shifting focus: Investigators describe changes to pancreatic β cells at onset of type 1 diabetes

by Joslin Diabetes CenterIn vivo AAV8-mediated overexpression of Mettl3 in NOD mouse β-cells delays T1D progression. Credit:Nature Cell Biology(2024). DOI: 10.1038/s41556-024-01368-0A

Updated on:March 14,2024

Gulf War Illness significantly reduces white blood cells' ability to make energy, study finds

byDuke UniversityUS Troops in the Persian Gulf War (1991). Gulf War Illness (GWI), which affects approximately 250,000 U.S. veterans, has been found to significantly reduce the ability of white

Updated on: January 09,2024

Gulf War Illness significantly reduces white blood cells' ability to make energy, study finds

byDuke UniversityUS Troops in the Persian Gulf War (1991). Gulf War Illness (GWI), which affects approximately 250,000 U.S. veterans, has been found to significantly reduce the ability of white

Updated on:January 09,2024

High out-of-pocket costs hindering treatment of diabetes

by University of MichiganHigh out-of-pocket costs hindering treatment of diabetes. Credit: Jacob Dwyer/Michigan MedicineActively managing diabetes is crucial to preventing long-term health compli

Updated on: March 14,2024

High out-of-pocket costs hindering treatment of diabetes

by University of MichiganHigh out-of-pocket costs hindering treatment of diabetes. Credit: Jacob Dwyer/Michigan MedicineActively managing diabetes is crucial to preventing long-term health compli

Updated on:March 14,2024

Scurvy: Not just an 18th-century sailors' disease

byCanadian Medical Association JournalCredit: Unsplash/CC0 Public DomainScurvy, or vitamin C deficiency, is not just an 18th-century seafarers' disease, as a case study of a 65-year-old woma

Updated on: November 11,2024

Scurvy: Not just an 18th-century sailors' disease

byCanadian Medical Association JournalCredit: Unsplash/CC0 Public DomainScurvy, or vitamin C deficiency, is not just an 18th-century seafarers' disease, as a case study of a 65-year-old woma

Updated on:November 11,2024

Study reveals the role of ERRγ in the regulation of FGF23 gene expression following acute liver injury

by TranSpreadCCl4-induced acute liver injury increases FGF23 gene expression and secretion in mouse liver through ERRγ. (A, B) Quantitative PCR analysis of total RNA obtained from the livers of mice i

Updated on: January 18,2024

Study reveals the role of ERRγ in the regulation of FGF23 gene expression following acute liver injury

by TranSpreadCCl4-induced acute liver injury increases FGF23 gene expression and secretion in mouse liver through ERRγ. (A, B) Quantitative PCR analysis of total RNA obtained from the livers of mice i

Updated on:January 18,2024

Study links hormones, blood sugar, blood lipids, and BMI to the severity of major depressive disorder and suicide risk

byAssociation of Basic Medical Sciences of FBIHHypothalamus-pituitary-adrenal axis (HPA axis) dysfunction is one of the important biochemical changes in depression. The development of depression

Updated on: January 22,2024

Study links hormones, blood sugar, blood lipids, and BMI to the severity of major depressive disorder and suicide risk

byAssociation of Basic Medical Sciences of FBIHHypothalamus-pituitary-adrenal axis (HPA axis) dysfunction is one of the important biochemical changes in depression. The development of depression

Updated on:January 22,2024

Stress from rising population numbers may cause a decline in human fertility

by The Endocrine SocietyCredit: CC0 Public DomainA predicted population drop at the end of the century could be explained by stress from meaningless social interactions, according to a review art

Updated on: February 21,2024

Stress from rising population numbers may cause a decline in human fertility

by The Endocrine SocietyCredit: CC0 Public DomainA predicted population drop at the end of the century could be explained by stress from meaningless social interactions, according to a review art

Updated on:February 21,2024

Stem cell 'messages' fast-track healing of diabetic wounds

by TranSpreadCredit:Burns & Trauma(2024). DOI: 10.1093/burnst/tkae001The increasing prevalence of diabetes worldwide has led to a rise in diabetic wounds, such as diabetic foot ulcers,

Updated on: March 27,2024

Stem cell 'messages' fast-track healing of diabetic wounds

by TranSpreadCredit:Burns & Trauma(2024). DOI: 10.1093/burnst/tkae001The increasing prevalence of diabetes worldwide has led to a rise in diabetic wounds, such as diabetic foot ulcers,

Updated on:March 27,2024

Some chronic disease medications found to impair the body's cooling ability

by Amanda Yap,National University of SingaporeCredit: Pixabay/CC0 Public DomainMedications to treat various chronic diseases may hinder the body's ability to lose heat and regulate its core

Updated on: January 24,2024

Some chronic disease medications found to impair the body's cooling ability

by Amanda Yap,National University of SingaporeCredit: Pixabay/CC0 Public DomainMedications to treat various chronic diseases may hinder the body's ability to lose heat and regulate its core

Updated on:January 24,2024

Tirzepatide has unique activity to stimulate insulin secretion, suggests study

by Duke University Medical CenterCredit: CC0 Public DomainTirzepatide, a drug approved for diabetes and on the fast track for approval as a weight loss therapy, works through a unique ability to

Updated on: February 21,2024

Tirzepatide has unique activity to stimulate insulin secretion, suggests study

by Duke University Medical CenterCredit: CC0 Public DomainTirzepatide, a drug approved for diabetes and on the fast track for approval as a weight loss therapy, works through a unique ability to

Updated on:February 21,2024

Higher blood fats more harmful than first thought

by University of LeedsMicroscopy image showing human muscle cells with nuclei in blue, and stress caused by the ceramide stress signals shown in red. Credit: Lee RobertsIncreased levels of blood

Updated on: January 31,2024

Higher blood fats more harmful than first thought

by University of LeedsMicroscopy image showing human muscle cells with nuclei in blue, and stress caused by the ceramide stress signals shown in red. Credit: Lee RobertsIncreased levels of blood

Updated on:January 31,2024

How a gut microbe can exacerbate obesity

by RIKENGraphical abstract. Credit:Cell Metabolism(2023). DOI: 10.1016/j.cmet.2022.12.013RIKEN researchers have discovered how a species of gut microbe exacerbates obesity in mice fed

Updated on: January 28,2024

How a gut microbe can exacerbate obesity

by RIKENGraphical abstract. Credit:Cell Metabolism(2023). DOI: 10.1016/j.cmet.2022.12.013RIKEN researchers have discovered how a species of gut microbe exacerbates obesity in mice fed

Updated on:January 28,2024