Shifting focus: Investigators describe changes to pancreatic β cells at onset of type 1 diabetes

by Joslin Diabetes CenterIn vivo AAV8-mediated overexpression of Mettl3 in NOD mouse β-cells delays T1D progression. Credit:Nature Cell Biology(2024). DOI: 10.1038/s41556-024-01368-0A

Updated on: March 14,2024

Shifting focus: Investigators describe changes to pancreatic β cells at onset of type 1 diabetes

by Joslin Diabetes CenterIn vivo AAV8-mediated overexpression of Mettl3 in NOD mouse β-cells delays T1D progression. Credit:Nature Cell Biology(2024). DOI: 10.1038/s41556-024-01368-0A

Updated on:March 14,2024

Study finds targeting mitochondria shows promise in treating obesity

by University of California, IrvineCredit: CC0 Public DomainA team of University of California, Irvine, scientists have discovered a novel pharmacological approach to attenuate the mitochondrial

Updated on: February 19,2024

Study finds targeting mitochondria shows promise in treating obesity

by University of California, IrvineCredit: CC0 Public DomainA team of University of California, Irvine, scientists have discovered a novel pharmacological approach to attenuate the mitochondrial

Updated on:February 19,2024

Researchers show how lipids and diabetes are closely linked

byUniversity of GenevaCredit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101299While sugar is the most frequently named culprit in the development of type 2 diabetes, a bet

Updated on: January 09,2024

Researchers show how lipids and diabetes are closely linked

byUniversity of GenevaCredit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101299While sugar is the most frequently named culprit in the development of type 2 diabetes, a bet

Updated on:January 09,2024

Pancreas 'crosstalk' may influence course of type 1 and type 2 diabetes

by Bill Snyder,Vanderbilt UniversityMethod for quantification of ADM lobules. ADM-positive lobules (outlined in green) were tallied per section. Total pancreatic tissue (orange) was outlined man

Updated on: January 09,2024

Pancreas 'crosstalk' may influence course of type 1 and type 2 diabetes

by Bill Snyder,Vanderbilt UniversityMethod for quantification of ADM lobules. ADM-positive lobules (outlined in green) were tallied per section. Total pancreatic tissue (orange) was outlined man

Updated on:January 09,2024

Peptide with anti-obesity action successfully tested in animal trial

by Thais Szegö,FAPESPChemical structure of Pep19. Credit: Researchers' archiveA study conducted at the University of São Paulo (USP) in Brazil shows that the synthetic molecule Pep19 acts on

Updated on: February 03,2024

Peptide with anti-obesity action successfully tested in animal trial

by Thais Szegö,FAPESPChemical structure of Pep19. Credit: Researchers' archiveA study conducted at the University of São Paulo (USP) in Brazil shows that the synthetic molecule Pep19 acts on

Updated on:February 03,2024

Some chronic disease medications found to impair the body's cooling ability

by Amanda Yap,National University of SingaporeCredit: Pixabay/CC0 Public DomainMedications to treat various chronic diseases may hinder the body's ability to lose heat and regulate its core

Updated on: January 24,2024

Some chronic disease medications found to impair the body's cooling ability

by Amanda Yap,National University of SingaporeCredit: Pixabay/CC0 Public DomainMedications to treat various chronic diseases may hinder the body's ability to lose heat and regulate its core

Updated on:January 24,2024

ER-positive breast cancer presents differing metabolic signatures in African American, white women: Study

by Sharita Forrest,University of Illinois at Urbana-Champaign(A) Boxplot of the relative concentration of 10 differential metabolites in AA individuals divided by cancer cases and healthy contro

Updated on: January 19,2024

ER-positive breast cancer presents differing metabolic signatures in African American, white women: Study

by Sharita Forrest,University of Illinois at Urbana-Champaign(A) Boxplot of the relative concentration of 10 differential metabolites in AA individuals divided by cancer cases and healthy contro

Updated on:January 19,2024

Novel insights into how muscles change during endurance training

by Katrin Bühler,University of BaselMuscles adapt to endurance training thus becoming more efficient and resilient. Credit: PixabayThe more we exercise our endurance, the fitter we become—and so

Updated on: January 20,2024

Novel insights into how muscles change during endurance training

by Katrin Bühler,University of BaselMuscles adapt to endurance training thus becoming more efficient and resilient. Credit: PixabayThe more we exercise our endurance, the fitter we become—and so

Updated on:January 20,2024

Many autoimmune disease patients struggle with diagnosis, costs, inattentive care

by Andy Miller, KFF Health NewsCredit: Pixabay/CC0 Public DomainAfter years of debilitating bouts of fatigue, Beth VanOrden finally thought she had an answer to her problems in 2016 when she was diagn

Updated on: January 09,2024

Many autoimmune disease patients struggle with diagnosis, costs, inattentive care

by Andy Miller, KFF Health NewsCredit: Pixabay/CC0 Public DomainAfter years of debilitating bouts of fatigue, Beth VanOrden finally thought she had an answer to her problems in 2016 when she was diagn

Updated on:January 09,2024

Link found between obesity during pregnancy and increased risk of sudden unexpected infant death

by Bob Yirka , Medical XpressCredit: CC0 Public DomainA multi-institutional team of statistical researchers has found a slightly heightened risk of sudden unexpected infant death (SUID) in babies born

Updated on: August 31,2024

Link found between obesity during pregnancy and increased risk of sudden unexpected infant death

by Bob Yirka , Medical XpressCredit: CC0 Public DomainA multi-institutional team of statistical researchers has found a slightly heightened risk of sudden unexpected infant death (SUID) in babies born

Updated on:August 31,2024

People with 'healthy obesity' are still at increased risk of disease

by DiabetologiaCredit: CC0 Public DomainA new study published inDiabetologiareveals that having a normal metabolic profile does not mean that a person with obesity is actually healthy

Updated on: February 03,2024

People with 'healthy obesity' are still at increased risk of disease

by DiabetologiaCredit: CC0 Public DomainA new study published inDiabetologiareveals that having a normal metabolic profile does not mean that a person with obesity is actually healthy

Updated on:February 03,2024

Investigating the role of DNA damage in cardiac hypertrophy

by Melissa Rohman,Northwestern UniversityRepresentative immunofluorescence images of H9c2 cardiomyoblast cells treated with control or Snrk siRNA and stained with Phalloidin-iFluor 488 to assess

Updated on: January 20,2024

Investigating the role of DNA damage in cardiac hypertrophy

by Melissa Rohman,Northwestern UniversityRepresentative immunofluorescence images of H9c2 cardiomyoblast cells treated with control or Snrk siRNA and stained with Phalloidin-iFluor 488 to assess

Updated on:January 20,2024