Shifting focus: Investigators describe changes to pancreatic β cells at onset of type 1 diabetes

by Joslin Diabetes CenterIn vivo AAV8-mediated overexpression of Mettl3 in NOD mouse β-cells delays T1D progression. Credit:Nature Cell Biology(2024). DOI: 10.1038/s41556-024-01368-0A

Updated on: March 14,2024

Shifting focus: Investigators describe changes to pancreatic β cells at onset of type 1 diabetes

by Joslin Diabetes CenterIn vivo AAV8-mediated overexpression of Mettl3 in NOD mouse β-cells delays T1D progression. Credit:Nature Cell Biology(2024). DOI: 10.1038/s41556-024-01368-0A

Updated on:March 14,2024

Understanding how exercise induces systemic metabolic benefits

by Olivia Dimmer,Northwestern UniversityGraphical abstract. Credit:Cell Metabolism(2023). DOI: 10.1016/j.cmet.2023.01.011Northwestern Medicine scientists have uncovered a mechanism b

Updated on: February 05,2024

Understanding how exercise induces systemic metabolic benefits

by Olivia Dimmer,Northwestern UniversityGraphical abstract. Credit:Cell Metabolism(2023). DOI: 10.1016/j.cmet.2023.01.011Northwestern Medicine scientists have uncovered a mechanism b

Updated on:February 05,2024

Abnormal lactate metabolism linked to kidney injury in diabetic patients

by Federico Graciano,Duke-NUS Medical SchoolCredit: Pixabay/CC0 Public DomainDisrupted kidney metabolism is a key driver of progressive kidney injury in diabetic kidney disease (DKD), according

Updated on: January 17,2024

Abnormal lactate metabolism linked to kidney injury in diabetic patients

by Federico Graciano,Duke-NUS Medical SchoolCredit: Pixabay/CC0 Public DomainDisrupted kidney metabolism is a key driver of progressive kidney injury in diabetic kidney disease (DKD), according

Updated on:January 17,2024

AI and machine learning can successfully diagnose polycystic ovary syndrome

byNational Institutes of HealthSelection process of the studies. Article selection flow chart for studies related to AI/ML and PCOS according to Preferred Reporting Items for Systematic Reviews

Updated on: January 18,2024

AI and machine learning can successfully diagnose polycystic ovary syndrome

byNational Institutes of HealthSelection process of the studies. Article selection flow chart for studies related to AI/ML and PCOS according to Preferred Reporting Items for Systematic Reviews

Updated on:January 18,2024

International comprehensive consensus issued on management of achondroplasia

by Nemours Children's Health SystemCredit: Pixabay/CC0 Public DomainFifty-five experts from 16 countries have collaborated on a new consensus statement on the management of achondroplasia (AC

Updated on: February 21,2024

International comprehensive consensus issued on management of achondroplasia

by Nemours Children's Health SystemCredit: Pixabay/CC0 Public DomainFifty-five experts from 16 countries have collaborated on a new consensus statement on the management of achondroplasia (AC

Updated on:February 21,2024

Scientists demonstrate a combination treatment can increase human insulin-producing cells in vivo

byThe Mount Sinai HospitalCredit: CC0 Public DomainIn preclinical studies, a team of researchers from Mount Sinai Health System in New York City and City of Hope in Los Angeles report new findin

Updated on: July 17,2024

Scientists demonstrate a combination treatment can increase human insulin-producing cells in vivo

byThe Mount Sinai HospitalCredit: CC0 Public DomainIn preclinical studies, a team of researchers from Mount Sinai Health System in New York City and City of Hope in Los Angeles report new findin

Updated on:July 17,2024

GLP-1 RA use tied to lower rate of venous thromboembolism in diabetes

by Elana GotkineFor patients with type 2 diabetes mellitus (T2DM), glucagon-like peptide 1 receptor agonist (GLP-1 RA) use is associated with a lower risk for venous thromboembolism (VTE), according t

Updated on: November 21,2024

GLP-1 RA use tied to lower rate of venous thromboembolism in diabetes

by Elana GotkineFor patients with type 2 diabetes mellitus (T2DM), glucagon-like peptide 1 receptor agonist (GLP-1 RA) use is associated with a lower risk for venous thromboembolism (VTE), according t

Updated on:November 21,2024

New study links high birth weight to childhood obesity in the US

by TranSpreadCredit: Pixabay/CC0 Public DomainA new studypublishedin the journalReproductive and Developmental Medicinehas found a strong association between fetal macrosomia (

Updated on: March 13,2024

New study links high birth weight to childhood obesity in the US

by TranSpreadCredit: Pixabay/CC0 Public DomainA new studypublishedin the journalReproductive and Developmental Medicinehas found a strong association between fetal macrosomia (

Updated on:March 13,2024

Single 'smart' insulin injection regulates glucose levels in mice and minipigs up to one week

by Bob Yirka , Medical XpressDually glucose-responsive complex for insulin delivery. Schematic of complex formation and insulin release with dual glucose-responsive mechanisms. The negatively charged

Updated on: March 14,2024

Single 'smart' insulin injection regulates glucose levels in mice and minipigs up to one week

by Bob Yirka , Medical XpressDually glucose-responsive complex for insulin delivery. Schematic of complex formation and insulin release with dual glucose-responsive mechanisms. The negatively charged

Updated on:March 14,2024

Researchers uncover mechanism for treating dangerous liver condition

by Steve Lundeberg,Oregon State UniversityNASH mouse model outlines all expression/omics data, DHA/EPA treatment effects on outcome. Credit:EMBO Molecular Medicine(2023). DOI: 10.152

Updated on: January 19,2024

Researchers uncover mechanism for treating dangerous liver condition

by Steve Lundeberg,Oregon State UniversityNASH mouse model outlines all expression/omics data, DHA/EPA treatment effects on outcome. Credit:EMBO Molecular Medicine(2023). DOI: 10.152

Updated on:January 19,2024

Unraveling the mechanism behind obesity-induced pancreatic β-cell dysfunction

byUniversity of TsukubaCredit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112914Obesity not only increases the risk of metabolic syndrome-related diseases, such as diabetes, fatty

Updated on: January 17,2024

Unraveling the mechanism behind obesity-induced pancreatic β-cell dysfunction

byUniversity of TsukubaCredit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112914Obesity not only increases the risk of metabolic syndrome-related diseases, such as diabetes, fatty

Updated on:January 17,2024

Worrying regional disparities found in lower limb amputation caused by arterial disease

by University of SheffieldPopulation-based AKA and BKA rates by age, sex and diabetes status; England (April 2006 to March 2018) AKA, above knee amputation; BKA, below knee amputation. Credit:&nb

Updated on: March 27,2024

Worrying regional disparities found in lower limb amputation caused by arterial disease

by University of SheffieldPopulation-based AKA and BKA rates by age, sex and diabetes status; England (April 2006 to March 2018) AKA, above knee amputation; BKA, below knee amputation. Credit:&nb

Updated on:March 27,2024