The spike of SARS-CoV-2 promotes metabolic rewiring in hepatocytes

by CIC bioGUNEProteomic analyses reveal changes in hACE2 mouse hepatocytes after infection with pseudotyped viral particles expressing the spike of SARS-CoV-2. a Volcano plot showing the 354 different

Updated on: January 28,2024

The spike of SARS-CoV-2 promotes metabolic rewiring in hepatocytes

by CIC bioGUNEProteomic analyses reveal changes in hACE2 mouse hepatocytes after infection with pseudotyped viral particles expressing the spike of SARS-CoV-2. a Volcano plot showing the 354 different

Updated on:January 28,2024

Researchers uncover how sugar substitutes disrupt liver detoxification

by Experimental BiologyNon-nutritive sweeteners (NNS) consumed in the diet enter the liver from the blood circulation. Researchers found that in liver cells, the detoxifying transporter P-glycoprotein

Updated on: February 21,2024

Researchers uncover how sugar substitutes disrupt liver detoxification

by Experimental BiologyNon-nutritive sweeteners (NNS) consumed in the diet enter the liver from the blood circulation. Researchers found that in liver cells, the detoxifying transporter P-glycoprotein

Updated on:February 21,2024

International comprehensive consensus issued on management of achondroplasia

by Nemours Children's Health SystemCredit: Pixabay/CC0 Public DomainFifty-five experts from 16 countries have collaborated on a new consensus statement on the management of achondroplasia (AC

Updated on: February 21,2024

International comprehensive consensus issued on management of achondroplasia

by Nemours Children's Health SystemCredit: Pixabay/CC0 Public DomainFifty-five experts from 16 countries have collaborated on a new consensus statement on the management of achondroplasia (AC

Updated on:February 21,2024

Cortisol is essential for a healthy stress response, say researchers

by Theresa Larkin and Susan J Thomas,The ConversationCredit:Kinga Howard/UnsplashHave you been craving certain foods and gaining weight? Maybe you're fatigued and can't concentrate

Updated on: February 21,2024

Cortisol is essential for a healthy stress response, say researchers

by Theresa Larkin and Susan J Thomas,The ConversationCredit:Kinga Howard/UnsplashHave you been craving certain foods and gaining weight? Maybe you're fatigued and can't concentrate

Updated on:February 21,2024

Uncovering how low-protein diets might reprogram metabolism

by Eric Hamilton,University of Wisconsin-MadisonCredit: CC0 Public DomainIn 2014, Dudley Lamming was readinga study out of Australiathat looked at how mice responded to dozens of con

Updated on: February 05,2024

Uncovering how low-protein diets might reprogram metabolism

by Eric Hamilton,University of Wisconsin-MadisonCredit: CC0 Public DomainIn 2014, Dudley Lamming was readinga study out of Australiathat looked at how mice responded to dozens of con

Updated on:February 05,2024

Metabolism changes with age, just not when you might think

by Duke University School of NursingCredit: CC0 Public DomainMost of us remember a time when we could eat anything we wanted and not gain weight. But a new study suggests your metabolism—the rate

Updated on: February 21,2024

Metabolism changes with age, just not when you might think

by Duke University School of NursingCredit: CC0 Public DomainMost of us remember a time when we could eat anything we wanted and not gain weight. But a new study suggests your metabolism—the rate

Updated on:February 21,2024

New biomarker for predicting non-lymphocytic lesions, including germinoma, in patients with central diabetes insipidus

byFujita Health UniversityMicroscopic image reveals the presence of germinomas in a clinical sample of central diabetes insipidus. Credit: Germinoma he x200Central diabetes insipidus (CDI), a ra

Updated on: January 09,2024

New biomarker for predicting non-lymphocytic lesions, including germinoma, in patients with central diabetes insipidus

byFujita Health UniversityMicroscopic image reveals the presence of germinomas in a clinical sample of central diabetes insipidus. Credit: Germinoma he x200Central diabetes insipidus (CDI), a ra

Updated on:January 09,2024

Type 1 diabetes research sheds light on biomarkers in partial remission phase

by Germans Trias i Pujol Research InstituteCredit: Unsplash/CC0 Public DomainResearchers from the Germans Trias i Pujol Research Institute (IGTP) have led a comprehensive review study on biomarkers fo

Updated on: January 09,2024

Type 1 diabetes research sheds light on biomarkers in partial remission phase

by Germans Trias i Pujol Research InstituteCredit: Unsplash/CC0 Public DomainResearchers from the Germans Trias i Pujol Research Institute (IGTP) have led a comprehensive review study on biomarkers fo

Updated on:January 09,2024

Hot flashes, yet another early indicator for Alzheimer's disease

byThe North American Menopause SocietyCredit: Unsplash/CC0 Public DomainAs if hot flashes alone weren't bad enough for women going through the menopause transition, a new study suggests that

Updated on: January 17,2024

Hot flashes, yet another early indicator for Alzheimer's disease

byThe North American Menopause SocietyCredit: Unsplash/CC0 Public DomainAs if hot flashes alone weren't bad enough for women going through the menopause transition, a new study suggests that

Updated on:January 17,2024

Researchers identify new mechanism that could improve the efficiency of diabetes treatments

by University of BarcelonaProposed mechanistic model for the hepatic effects of Gdf15 deficiency on fibrosis, gluconeogenesis and fatty liver via the TGF-β1-SMAD3 pathway. Credit:Metabolism

Updated on: March 05,2024

Researchers identify new mechanism that could improve the efficiency of diabetes treatments

by University of BarcelonaProposed mechanistic model for the hepatic effects of Gdf15 deficiency on fibrosis, gluconeogenesis and fatty liver via the TGF-β1-SMAD3 pathway. Credit:Metabolism

Updated on:March 05,2024

ABarginase, the first-in-class drug for multiple obesity-related metabolic diseases

by Hong Kong Polytechnic University3D molecular models of ABarginase, albumin and FcRn receptor on a cell surface. Credit: Hong Kong Polytechnic UniversityResearchers from The Hong Kong Polytechn

Updated on: February 05,2024

ABarginase, the first-in-class drug for multiple obesity-related metabolic diseases

by Hong Kong Polytechnic University3D molecular models of ABarginase, albumin and FcRn receptor on a cell surface. Credit: Hong Kong Polytechnic UniversityResearchers from The Hong Kong Polytechn

Updated on:February 05,2024

An important step toward next-generation probiotics

by University of GothenburgCo-isolation and cross-feeding ofF. prausnitziiandD. pigerin vitro.a, Co-culture ofF. prausnitziiDSM 32186 andD. piger&n

Updated on: May 29,2024

An important step toward next-generation probiotics

by University of GothenburgCo-isolation and cross-feeding ofF. prausnitziiandD. pigerin vitro.a, Co-culture ofF. prausnitziiDSM 32186 andD. piger&n

Updated on:May 29,2024