Gut microbes may determine patients' response to a drug that delays onset of type 1 diabetes

by Delthia Ricks , Medical XpressTeplizumab delays type 1 diabetes (T1D) in at-risk individuals in TN10 trial, but participants respond differently to the treatment. Systemic, non-pathogenic antibody

Updated on: March 14,2024 20

Gut microbes may determine patients' response to a drug that delays onset of type 1 diabetes

by Delthia Ricks , Medical XpressTeplizumab delays type 1 diabetes (T1D) in at-risk individuals in TN10 trial, but participants respond differently to the treatment. Systemic, non-pathogenic antibody

Updated on:March 14,2024 20

Unveiling a new mechanism that accelerates aging of adipose tissues

Unveiling a new mechanism that accelerates aging of adipose tissuesbyPohang University of Science and TechnologyMetabolic phenotype affected by aging and adipocyte-specific Crtc2 knockout. Adipo

Updated on: January 24,2024 10

Unveiling a new mechanism that accelerates aging of adipose tissues

Unveiling a new mechanism that accelerates aging of adipose tissuesbyPohang University of Science and TechnologyMetabolic phenotype affected by aging and adipocyte-specific Crtc2 knockout. Adipo

Updated on:January 24,2024 10

Is menopause making me put on weight? No, but it's complicated

by Nick Fuller,The ConversationCredit: AI-generated imageIt's a question people ask often: does menopause cause weight gain?Women commonly put onweightas they entermenopaus

Updated on: January 31,2024 21

Is menopause making me put on weight? No, but it's complicated

by Nick Fuller,The ConversationCredit: AI-generated imageIt's a question people ask often: does menopause cause weight gain?Women commonly put onweightas they entermenopaus

Updated on:January 31,2024 21

Preservation of C-peptide secretion examined in youth with type 1 diabetes

Intensive glucose control for 24 months does not slow the decline in residual C-peptide secretion among youth with new-onset type 1 diabetes, according to a study published in the Sept. 8 issue of the

Updated on: July 01,2024 8

Preservation of C-peptide secretion examined in youth with type 1 diabetes

Intensive glucose control for 24 months does not slow the decline in residual C-peptide secretion among youth with new-onset type 1 diabetes, according to a study published in the Sept. 8 issue of the

Updated on:July 01,2024 8

Intestinal bacteria release molecular 'brake' on weight gain, study finds

byUT Southwestern Medical CenterSecondary structure of long non-coding RNA Snhg9. (A) Secondary structure of Snhg9 RNA predicted by RNAfold (49) with nucleotide positions indicated. (B) Location

Updated on: January 17,2024 16

Intestinal bacteria release molecular 'brake' on weight gain, study finds

byUT Southwestern Medical CenterSecondary structure of long non-coding RNA Snhg9. (A) Secondary structure of Snhg9 RNA predicted by RNAfold (49) with nucleotide positions indicated. (B) Location

Updated on:January 17,2024 16

Researchers investigate the multi-omic landscape of steatosis-to-NASH progression in mice

by Higher Education PressPlasma GDF3 levels are significantly associated with histologic features in patients with NASH. Credit:Life Metabolism(2022). DOI: 10.1093/lifemeta/loac034The glob

Updated on: February 19,2024 14

Researchers investigate the multi-omic landscape of steatosis-to-NASH progression in mice

by Higher Education PressPlasma GDF3 levels are significantly associated with histologic features in patients with NASH. Credit:Life Metabolism(2022). DOI: 10.1093/lifemeta/loac034The glob

Updated on:February 19,2024 14

Humanized mice reveal arsenic may raise diabetes risk only for males

by Krishna Ramanujan,Cornell UniversityMeasuring arsenic in liver and adipose tissue of humanized and wild-type mice. (A) Arsenical quantification in isolated liver of mice (WT male, n=5; WT fem

Updated on: March 14,2024 15

Humanized mice reveal arsenic may raise diabetes risk only for males

by Krishna Ramanujan,Cornell UniversityMeasuring arsenic in liver and adipose tissue of humanized and wild-type mice. (A) Arsenical quantification in isolated liver of mice (WT male, n=5; WT fem

Updated on:March 14,2024 15

Study shows that AgRP neurons encode circadian feeding time in mice

by Ingrid Fadelli , Medical XpressImage of the AgRP neurons. Credit: Hyojin Kim (University of Iowa).Animals and humans follow specific daily patterns known as circadian rhythms, which naturally promp

Updated on: January 19,2024 15

Study shows that AgRP neurons encode circadian feeding time in mice

by Ingrid Fadelli , Medical XpressImage of the AgRP neurons. Credit: Hyojin Kim (University of Iowa).Animals and humans follow specific daily patterns known as circadian rhythms, which naturally promp

Updated on:January 19,2024 15

Mouse model of transgender men finds active testosterone worsens IVF outcomes

by The Endocrine SocietyCredit: CC0 Public DomainActive testosterone therapy for transgender men may negatively impact IVF outcomes, suggests a mouse study being presented Monday at ENDO 2022, th

Updated on: February 03,2024 12

Mouse model of transgender men finds active testosterone worsens IVF outcomes

by The Endocrine SocietyCredit: CC0 Public DomainActive testosterone therapy for transgender men may negatively impact IVF outcomes, suggests a mouse study being presented Monday at ENDO 2022, th

Updated on:February 03,2024 12

How a high fat diet allows expulsion of intestinal parasite worms

by Lancaster UniversityHigh fat diet induced obesity protects mice from chronic T. muris infection. Percentage change in basal start weight in wild-type C57BL/6 mice receiving 12 weeks of CD or H

Updated on: June 17,2024 8

How a high fat diet allows expulsion of intestinal parasite worms

by Lancaster UniversityHigh fat diet induced obesity protects mice from chronic T. muris infection. Percentage change in basal start weight in wild-type C57BL/6 mice receiving 12 weeks of CD or H

Updated on:June 17,2024 8

Does maternal obesity during pregnancy impact offspring's liver and skeletal muscle metabolism?

by WileyCredit:The FASEB Journal(2022). DOI: 10.1096/fj.202201473RA recent study inThe FASEB Journalhas identified metabolic perturbations in the liver and skeletal muscle

Updated on: February 19,2024 17

Does maternal obesity during pregnancy impact offspring's liver and skeletal muscle metabolism?

by WileyCredit:The FASEB Journal(2022). DOI: 10.1096/fj.202201473RA recent study inThe FASEB Journalhas identified metabolic perturbations in the liver and skeletal muscle

Updated on:February 19,2024 17

Metabolic remodeling during early mouse embryo development

by Zhejiang UniversityCredit: CC0 Public DomainA research team led by Prof. Zhang Jin from the Zhejiang University School of Medicine and the team led by Dr. Hu Zeping from the Tsinghua University Sch

Updated on: February 21,2024 17

Metabolic remodeling during early mouse embryo development

by Zhejiang UniversityCredit: CC0 Public DomainA research team led by Prof. Zhang Jin from the Zhejiang University School of Medicine and the team led by Dr. Hu Zeping from the Tsinghua University Sch

Updated on:February 21,2024 17