YBX1 as a key regulator of mitochondrial pyruvate uptake

by Frontiers JournalsYBX1 resides in the mitochondrial IMS. (a) Representative images of colocalization of YBX1 and PDHA1 in MDA-MB-231, MHCC-97H, and HEK293T cells. Red indicates YBX1 and green indic

Updated on: January 18,2024

YBX1 as a key regulator of mitochondrial pyruvate uptake

by Frontiers JournalsYBX1 resides in the mitochondrial IMS. (a) Representative images of colocalization of YBX1 and PDHA1 in MDA-MB-231, MHCC-97H, and HEK293T cells. Red indicates YBX1 and green indic

Updated on:January 18,2024

Synergistic effect of a traditional Chinese medicinal compound on existing diabetes drug found

by Justin Jackson , Medical XpressDiscovery and inhibition of a gut microbial–host isozyme to regulate host metabolism. Differences in the gut microbiota may explain why some individuals respond to an

Updated on: January 24,2024

Synergistic effect of a traditional Chinese medicinal compound on existing diabetes drug found

by Justin Jackson , Medical XpressDiscovery and inhibition of a gut microbial–host isozyme to regulate host metabolism. Differences in the gut microbiota may explain why some individuals respond to an

Updated on:January 24,2024

Thyroid hormone replacement undertreatment linked to worse hospital outcomes

by The Endocrine SocietyCredit: Pixabay/CC0 Public DomainUndertreatment with thyroid hormone replacement can put patients with hypothyroidism at risk for worse hospital outcomes, including longer

Updated on: February 03,2024

Thyroid hormone replacement undertreatment linked to worse hospital outcomes

by The Endocrine SocietyCredit: Pixabay/CC0 Public DomainUndertreatment with thyroid hormone replacement can put patients with hypothyroidism at risk for worse hospital outcomes, including longer

Updated on:February 03,2024

Drunk mice sober up after a hormone shot

by Cell PressFGF21 counteracts alcohol intoxication by activating the noradrenergic nervous system. Credit:Cell Metabolism/Choi et al.A hormone called fibroblast growth factor 21 (FGF21) pr

Updated on: February 03,2024

Drunk mice sober up after a hormone shot

by Cell PressFGF21 counteracts alcohol intoxication by activating the noradrenergic nervous system. Credit:Cell Metabolism/Choi et al.A hormone called fibroblast growth factor 21 (FGF21) pr

Updated on:February 03,2024

First patient receives Moderna mRNA trial infusion for glycogen storage disease

by Jennifer Walker,University of ConnecticutLove Joy, a nurse at UConn Health takes Loveah Hernandez's blood pressure. Credit: Shaylee KingPrior to COVID-19 vaccines most people had never he

Updated on: February 03,2024

First patient receives Moderna mRNA trial infusion for glycogen storage disease

by Jennifer Walker,University of ConnecticutLove Joy, a nurse at UConn Health takes Loveah Hernandez's blood pressure. Credit: Shaylee KingPrior to COVID-19 vaccines most people had never he

Updated on:February 03,2024

Hepatic hydrogen sulfide levels are reduced in mouse model of progeria

by Impact Journals LLCHepatic protein levels of H2S producing enzymes. Credit: 2023 Wilkie et al.Hutchinson-Gilford progeria syndrome (HGPS) is a rare human disease characterized by accelerated biolog

Updated on: January 22,2024

Hepatic hydrogen sulfide levels are reduced in mouse model of progeria

by Impact Journals LLCHepatic protein levels of H2S producing enzymes. Credit: 2023 Wilkie et al.Hutchinson-Gilford progeria syndrome (HGPS) is a rare human disease characterized by accelerated biolog

Updated on:January 22,2024

How the ACE2 protein is critical in the damage done to the insulin-producing cells of the pancreas

byDiabetologiaThe detailed mechanism of how SARS-CoV-2 attacks the insulin-producing cells of the pancreas by targeting the angiotensin converting enzyme 2 (ACE2) protein on the surface of those

Updated on: January 27,2024

How the ACE2 protein is critical in the damage done to the insulin-producing cells of the pancreas

byDiabetologiaThe detailed mechanism of how SARS-CoV-2 attacks the insulin-producing cells of the pancreas by targeting the angiotensin converting enzyme 2 (ACE2) protein on the surface of those

Updated on:January 27,2024

Researchers have uncovered a regulator of body weight that could lead to new treatments for metabolic disorders

by Yale UniversityCredit: Pixabay/CC0 Public DomainYale scientists have discovered that a protein known as augmentor-alpha regulates body weight in mice, an insight that could lead to new treatme

Updated on: February 19,2024

Researchers have uncovered a regulator of body weight that could lead to new treatments for metabolic disorders

by Yale UniversityCredit: Pixabay/CC0 Public DomainYale scientists have discovered that a protein known as augmentor-alpha regulates body weight in mice, an insight that could lead to new treatme

Updated on:February 19,2024

Endocrine-disrupting chemicals may impair bone health in male teens

by The Endocrine SocietyCredit: Unsplash/CC0 Public DomainPer- and polyfluoroalkyl substances (PFAS) and phthalates (two types of endocrine-disrupting chemicals) may be associated with lower bone

Updated on: January 31,2024

Endocrine-disrupting chemicals may impair bone health in male teens

by The Endocrine SocietyCredit: Unsplash/CC0 Public DomainPer- and polyfluoroalkyl substances (PFAS) and phthalates (two types of endocrine-disrupting chemicals) may be associated with lower bone

Updated on:January 31,2024

Acetate controls endothelial-to-mesenchymal transition: Potential therapeutic target for reducing atherosclerosis

by Yale School of MedicineGraphical abstract. Credit:Cell Metabolism(2023). DOI: 10.1016/j.cmet.2023.05.010In a new study, researchers including Yale School of Medicine's Michael Simon

Updated on: January 24,2024

Acetate controls endothelial-to-mesenchymal transition: Potential therapeutic target for reducing atherosclerosis

by Yale School of MedicineGraphical abstract. Credit:Cell Metabolism(2023). DOI: 10.1016/j.cmet.2023.05.010In a new study, researchers including Yale School of Medicine's Michael Simon

Updated on:January 24,2024

Century-old vaccine found to protect type 1 diabetics from infectious diseases

byMassachusetts General HospitalGraphical abstract. Credit:iScience(2024). DOI: 10.1016/j.isci.2024.109881In new research, investigators at Massachusetts General Hospital (MGH) show

Updated on: May 30,2024

Century-old vaccine found to protect type 1 diabetics from infectious diseases

byMassachusetts General HospitalGraphical abstract. Credit:iScience(2024). DOI: 10.1016/j.isci.2024.109881In new research, investigators at Massachusetts General Hospital (MGH) show

Updated on:May 30,2024

Parathyroidectomy no better for mild primary hyperparathyroidism

For patients with mild primary hyperparathyroidism (PHPT), outcomes at 10 years do not differ for parathyroidectomy (PTX) compared with observation without intervention (OBS), according to a study pub

Updated on: February 03,2024

Parathyroidectomy no better for mild primary hyperparathyroidism

For patients with mild primary hyperparathyroidism (PHPT), outcomes at 10 years do not differ for parathyroidectomy (PTX) compared with observation without intervention (OBS), according to a study pub

Updated on:February 03,2024