For the first time, researchers visualize metabolic process at the single-cell level

byUniversity of ChicagoA new PME imaging and machine learning technique can measure glycolysis at both the cellular and sub-cellular levels, potentially leading to new methods for treating a wid

Updated on: February 21,2024

For the first time, researchers visualize metabolic process at the single-cell level

byUniversity of ChicagoA new PME imaging and machine learning technique can measure glycolysis at both the cellular and sub-cellular levels, potentially leading to new methods for treating a wid

Updated on:February 21,2024

Scientists create first humanized mouse model for rare genetic disease

by European Society of EndocrinologyCredit: CC0 Public DomainMice with a defective human gene responsible for a rare genetic disease called congenital adrenal hyperplasia, have been developed for the

Updated on: February 03,2024

Scientists create first humanized mouse model for rare genetic disease

by European Society of EndocrinologyCredit: CC0 Public DomainMice with a defective human gene responsible for a rare genetic disease called congenital adrenal hyperplasia, have been developed for the

Updated on:February 03,2024

While waiting for food: The surprising fetal gut cells that make insulin

by Weizmann Institute of ScienceIn both the FIKL cells in the small intestine (top) and beta cells in the pancreas (bottom), the mRNA molecules for making insulin (magenta) are found closer to th

Updated on: January 31,2024

While waiting for food: The surprising fetal gut cells that make insulin

by Weizmann Institute of ScienceIn both the FIKL cells in the small intestine (top) and beta cells in the pancreas (bottom), the mRNA molecules for making insulin (magenta) are found closer to th

Updated on:January 31,2024

Letting go of extra weight to control sleeping sickness

byInstituto de Medicina MolecularProtective effect of adipocyte lipolysis in murine T. brucei infection. Graphical representation of the effects of ATGL-dependent lipolysis. ATGL activity promot

Updated on: January 17,2024

Letting go of extra weight to control sleeping sickness

byInstituto de Medicina MolecularProtective effect of adipocyte lipolysis in murine T. brucei infection. Graphical representation of the effects of ATGL-dependent lipolysis. ATGL activity promot

Updated on:January 17,2024

Researchers determine timing is key for type 2 diabetes drug performance

by Rhiannon Koch,University of AdelaideStudy protocol. Credit:Diabetologia(2024). DOI: 10.1007/s00125-024-06131-6Researchers from the University of Adelaide could be closer to discov

Updated on: June 18,2024

Researchers determine timing is key for type 2 diabetes drug performance

by Rhiannon Koch,University of AdelaideStudy protocol. Credit:Diabetologia(2024). DOI: 10.1007/s00125-024-06131-6Researchers from the University of Adelaide could be closer to discov

Updated on:June 18,2024

A new injectable shows promise to prevent and treat hypoglycemia

byAmerican Chemical SocietyEncapsulated glucagon for insulin-induced hypoglycemia dissolves when sugar levels get seriously low (less than 60 milligrams per deciliter, mg/dL), releasing the horm

Updated on: October 09,2024

A new injectable shows promise to prevent and treat hypoglycemia

byAmerican Chemical SocietyEncapsulated glucagon for insulin-induced hypoglycemia dissolves when sugar levels get seriously low (less than 60 milligrams per deciliter, mg/dL), releasing the horm

Updated on:October 09,2024

Unveiling a new mechanism that accelerates aging of adipose tissues

Unveiling a new mechanism that accelerates aging of adipose tissuesbyPohang University of Science and TechnologyMetabolic phenotype affected by aging and adipocyte-specific Crtc2 knockout. Adipo

Updated on: January 24,2024

Unveiling a new mechanism that accelerates aging of adipose tissues

Unveiling a new mechanism that accelerates aging of adipose tissuesbyPohang University of Science and TechnologyMetabolic phenotype affected by aging and adipocyte-specific Crtc2 knockout. Adipo

Updated on:January 24,2024

Scientists redefine obesity with discovery of two major subtypes

by Van Andel Research InstituteDysregulated HDAC-related transcriptome precedes the Nnat+/-p-overgrowth. a, Venn diagram of differential gene expression analyses of islets transcriptome of 6 week

Updated on: February 03,2024

Scientists redefine obesity with discovery of two major subtypes

by Van Andel Research InstituteDysregulated HDAC-related transcriptome precedes the Nnat+/-p-overgrowth. a, Venn diagram of differential gene expression analyses of islets transcriptome of 6 week

Updated on:February 03,2024

New hope for patients with hereditary metabolic disease

by Fabio Bergamin,ETH ZurichIn methylmalonic aciduria, a specific metabolite accumulates in the body. This often leads to patients requiring intensive medical care. Credit: University Children&#

Updated on: February 19,2024

New hope for patients with hereditary metabolic disease

by Fabio Bergamin,ETH ZurichIn methylmalonic aciduria, a specific metabolite accumulates in the body. This often leads to patients requiring intensive medical care. Credit: University Children&#

Updated on:February 19,2024

Discovery could help reduce adverse side effects of popular next-generation obesity medications

byMonell Chemical Senses CenterActivating GLP1 receptor-expressing neurons in the nucleus tractus solitarius (magenta) increase sateity without causing nausea or aversion. Credit: Alisha Acosta,

Updated on: July 11,2024

Discovery could help reduce adverse side effects of popular next-generation obesity medications

byMonell Chemical Senses CenterActivating GLP1 receptor-expressing neurons in the nucleus tractus solitarius (magenta) increase sateity without causing nausea or aversion. Credit: Alisha Acosta,

Updated on:July 11,2024

Excess calories during development may alter the brain and spur adult overeating

by Rutgers UniversityBNST→LHA connectivity is primarily GABAergic and is negatively correlated with early life growth rate. A. Experimental schematic. AAV-Syn-ChR2-eYFP was injected in BNST. B. E

Updated on: February 03,2024

Excess calories during development may alter the brain and spur adult overeating

by Rutgers UniversityBNST→LHA connectivity is primarily GABAergic and is negatively correlated with early life growth rate. A. Experimental schematic. AAV-Syn-ChR2-eYFP was injected in BNST. B. E

Updated on:February 03,2024

Metabolic signature can help predict which smokers will develop type 2 diabetes

byDiabetologiaCredit: Unsplash/CC0 Public DomainNew research being presented at this year'sAnnual Meeting of The European Association for the Study of Diabetes (EASD)in Hamburg (

Updated on: January 18,2024

Metabolic signature can help predict which smokers will develop type 2 diabetes

byDiabetologiaCredit: Unsplash/CC0 Public DomainNew research being presented at this year'sAnnual Meeting of The European Association for the Study of Diabetes (EASD)in Hamburg (

Updated on:January 18,2024