Scientists discover roles of hypothalamic amino acid sensing in antidepressant effects

by Higher Education PressDeprivation of an essential amino acid leucine exhibits antidepressant effects under chronic stress by stimulating GCN2 and neural activity in AgRP neurons. Credit: Feixiang Y

Updated on: February 03,2024

Scientists discover roles of hypothalamic amino acid sensing in antidepressant effects

by Higher Education PressDeprivation of an essential amino acid leucine exhibits antidepressant effects under chronic stress by stimulating GCN2 and neural activity in AgRP neurons. Credit: Feixiang Y

Updated on:February 03,2024

Treating acne with systemic antibiotics can have unintended consequences on maturing adolescent skeleton

by Medical University of South CarolinaCredit:JCIInsight(2022).DOI:10.1172/jci.insight.160578During adolescence, sex hormones drive significant physiologic changes. One of the most un

Updated on: February 21,2024

Treating acne with systemic antibiotics can have unintended consequences on maturing adolescent skeleton

by Medical University of South CarolinaCredit:JCIInsight(2022).DOI:10.1172/jci.insight.160578During adolescence, sex hormones drive significant physiologic changes. One of the most un

Updated on:February 21,2024

Weight loss program shown to improve eating disorder symptoms in at-risk people with type 2 diabetes

Updated on: June 25,2025

Weight loss program shown to improve eating disorder symptoms in at-risk people with type 2 diabetes

Updated on:June 25,2025

Excess calories during development may alter the brain and spur adult overeating

by Rutgers UniversityBNST→LHA connectivity is primarily GABAergic and is negatively correlated with early life growth rate. A. Experimental schematic. AAV-Syn-ChR2-eYFP was injected in BNST. B. E

Updated on: February 03,2024

Excess calories during development may alter the brain and spur adult overeating

by Rutgers UniversityBNST→LHA connectivity is primarily GABAergic and is negatively correlated with early life growth rate. A. Experimental schematic. AAV-Syn-ChR2-eYFP was injected in BNST. B. E

Updated on:February 03,2024

Scientists study links between obesity, age and body chemistry

by Clemson UniversityComparison of total body, liver, and WAT weights between all treatment groups. Total body weight, liver weight, hepatic somatic index (HSI), WAT weight, and WAT somatic index

Updated on: February 05,2024

Scientists study links between obesity, age and body chemistry

by Clemson UniversityComparison of total body, liver, and WAT weights between all treatment groups. Total body weight, liver weight, hepatic somatic index (HSI), WAT weight, and WAT somatic index

Updated on:February 05,2024

Longer siestas linked to higher risk of obesity, metabolic syndrome and high blood pressure

byBrigham and Women's Hospital(A) Mediated total effect of long siestas vs. no siesta on BMI. (B) Mediated total effect of long siestas vs. no siesta on glucose. (C) Mediated total effect of

Updated on: February 21,2024

Longer siestas linked to higher risk of obesity, metabolic syndrome and high blood pressure

byBrigham and Women's Hospital(A) Mediated total effect of long siestas vs. no siesta on BMI. (B) Mediated total effect of long siestas vs. no siesta on glucose. (C) Mediated total effect of

Updated on:February 21,2024

Study first to use novel glucagon isotopes to measure glucagon metabolism in Type 1 diabetes

Updated on: June 25,2025

Study first to use novel glucagon isotopes to measure glucagon metabolism in Type 1 diabetes

Updated on:June 25,2025

Scientists redefine obesity with discovery of two major subtypes

by Van Andel Research InstituteDysregulated HDAC-related transcriptome precedes the Nnat+/-p-overgrowth. a, Venn diagram of differential gene expression analyses of islets transcriptome of 6 week

Updated on: February 03,2024

Scientists redefine obesity with discovery of two major subtypes

by Van Andel Research InstituteDysregulated HDAC-related transcriptome precedes the Nnat+/-p-overgrowth. a, Venn diagram of differential gene expression analyses of islets transcriptome of 6 week

Updated on:February 03,2024

What is type 1.5 diabetes? It's a bit like type 1 and a bit like type 2—but it's often misdiagnosed

by Emily Burch and Lauren Ball,The ConversationCredit: Pixabay/CC0 Public DomainWhile you're likely familiar with type 1 and type 2 diabetes, you've probably heard less about type 1.5 di

Updated on: September 02,2024

What is type 1.5 diabetes? It's a bit like type 1 and a bit like type 2—but it's often misdiagnosed

by Emily Burch and Lauren Ball,The ConversationCredit: Pixabay/CC0 Public DomainWhile you're likely familiar with type 1 and type 2 diabetes, you've probably heard less about type 1.5 di

Updated on:September 02,2024

Could cholesterol explain why childhood obesity leads to early puberty?

by University of CopenhagenDietary cholesterol systemically promotes growth through insulin signaling(A) Larval growth on synthetic medium, reflected in pupal size, increases with increasing diet

Updated on: February 03,2024

Could cholesterol explain why childhood obesity leads to early puberty?

by University of CopenhagenDietary cholesterol systemically promotes growth through insulin signaling(A) Larval growth on synthetic medium, reflected in pupal size, increases with increasing diet

Updated on:February 03,2024

Direct-to-consumer online platforms expand access, but often fail to convey risks of testosterone therapy

by Northwestern Memorial HealthCareCredit: Unsplash/CC0 Public DomainDemand for testosterone therapy has soared in the United States with more men seeking to increase hormone levels in hopes of enhanc

Updated on: February 19,2024

Direct-to-consumer online platforms expand access, but often fail to convey risks of testosterone therapy

by Northwestern Memorial HealthCareCredit: Unsplash/CC0 Public DomainDemand for testosterone therapy has soared in the United States with more men seeking to increase hormone levels in hopes of enhanc

Updated on:February 19,2024

Metabolism may be key to future treatment of kidney diseases

by Aarhus UniversityCredit: Pixabay/CC0 Public DomainCan you eat your way out of a kidney disease? Perhaps you can—according to a new study from Aarhus University.In the study, Associate Professo

Updated on: January 31,2024

Metabolism may be key to future treatment of kidney diseases

by Aarhus UniversityCredit: Pixabay/CC0 Public DomainCan you eat your way out of a kidney disease? Perhaps you can—according to a new study from Aarhus University.In the study, Associate Professo

Updated on:January 31,2024