Dietary pyruvate targets cytosolic phospholipase A2 to mitigate inflammation and obesity in mice

by Higher Education PressThe mechanism of action of pyruvate by targeting cPLA2 and inhibiting cPLA2-mediated downstream signaling. Credit: Sadaf Hasan, Nabil Ghani, Xiangli Zhao, Julia Good, Amanda H

Updated on: July 25,2024

Dietary pyruvate targets cytosolic phospholipase A2 to mitigate inflammation and obesity in mice

by Higher Education PressThe mechanism of action of pyruvate by targeting cPLA2 and inhibiting cPLA2-mediated downstream signaling. Credit: Sadaf Hasan, Nabil Ghani, Xiangli Zhao, Julia Good, Amanda H

Updated on:July 25,2024

Blood test could determine diabetes risks

by Edith Cowan UniversityCumulative incidence of type 2 diabetes across CumCRP-by-CumMHR strata.G1 CumCRP < 1mg/L & CumMHR < 0.2340; G2 1 ≤ CumCRP < 3mg/L & Cum

Updated on: March 14,2024

Blood test could determine diabetes risks

by Edith Cowan UniversityCumulative incidence of type 2 diabetes across CumCRP-by-CumMHR strata.G1 CumCRP < 1mg/L & CumMHR < 0.2340; G2 1 ≤ CumCRP < 3mg/L & Cum

Updated on:March 14,2024

Metabolites may be better indicator than self-reported information for adherence to Mediterranean diet during pregnancy

by National University of SingaporeVolcano plots showing individual metabolite associated with peri-conception and first trimester alternate Mediterranean Diet (aMED) score reported at 8–13 weeks

Updated on: January 31,2024

Metabolites may be better indicator than self-reported information for adherence to Mediterranean diet during pregnancy

by National University of SingaporeVolcano plots showing individual metabolite associated with peri-conception and first trimester alternate Mediterranean Diet (aMED) score reported at 8–13 weeks

Updated on:January 31,2024

Offspring of people who were obese as teens are likely to be obese as well, study finds

by Bob Yirka , Medical XpressMean Body Mass Index (BMI) Distribution of Offspring According to Maternal and Paternal BMI Status. Analyses are based on 447,883 complete parent-offspring (of both sexes)

Updated on: July 08,2024

Offspring of people who were obese as teens are likely to be obese as well, study finds

by Bob Yirka , Medical XpressMean Body Mass Index (BMI) Distribution of Offspring According to Maternal and Paternal BMI Status. Analyses are based on 447,883 complete parent-offspring (of both sexes)

Updated on:July 08,2024

Extracellular vesicles offer new insights into treating endocrine disorders

by The Endocrine SocietyCredit: Pixabay/CC0 Public DomainIn a new Scientific Statement released today, the Endocrine Society describes the importance of extracellular vesicles as a new research t

Updated on: February 19,2024

Extracellular vesicles offer new insights into treating endocrine disorders

by The Endocrine SocietyCredit: Pixabay/CC0 Public DomainIn a new Scientific Statement released today, the Endocrine Society describes the importance of extracellular vesicles as a new research t

Updated on:February 19,2024

Molecule boosts fat burning

by University of BonnHuman brown adipocytes, lipid stained red (RedO oil stain). Credit: Laia Reverte Salisa / University of BonnNormally, fat cells store energy. In brown fat cells, however, ene

Updated on: February 03,2024

Molecule boosts fat burning

by University of BonnHuman brown adipocytes, lipid stained red (RedO oil stain). Credit: Laia Reverte Salisa / University of BonnNormally, fat cells store energy. In brown fat cells, however, ene

Updated on:February 03,2024

Study links intestinal glycan modifications to obesity and inflammation

byChiba UniversityChst4–/–mice lacking GlcNAc-6-O-sulfation of the mucinO-glycans showed significant weight gain, increased intestinal inflammation, and significantly reduced immunoglobuli

Updated on: January 18,2024

Study links intestinal glycan modifications to obesity and inflammation

byChiba UniversityChst4–/–mice lacking GlcNAc-6-O-sulfation of the mucinO-glycans showed significant weight gain, increased intestinal inflammation, and significantly reduced immunoglobuli

Updated on:January 18,2024

Obesity alters molecular architecture of liver cells. Repairing structure reverses metabolic disease

by Harvard School of Public HealthThe endoplasmic reticulum (ER) is white and lipid droplets appear yellow In this three-dimensional image of the interior of a diseased mouse liver cell created b

Updated on: January 31,2024

Obesity alters molecular architecture of liver cells. Repairing structure reverses metabolic disease

by Harvard School of Public HealthThe endoplasmic reticulum (ER) is white and lipid droplets appear yellow In this three-dimensional image of the interior of a diseased mouse liver cell created b

Updated on:January 31,2024

It's time to rethink our attitude toward obesity, academic argues

byTaylor & FrancisCredit: Pixabay from PexelsPrejudice against fat people is endemic in our society and public health initiatives aimed at reducing obesity have only worsened the problem, ac

Updated on: July 09,2024

It's time to rethink our attitude toward obesity, academic argues

byTaylor & FrancisCredit: Pixabay from PexelsPrejudice against fat people is endemic in our society and public health initiatives aimed at reducing obesity have only worsened the problem, ac

Updated on:July 09,2024

Do-It-Yourself artificial pancreas given approval by team of experts

by King's College LondonCredit: CC0 Public DomainMore than 40 healthcare professionals and legal experts have issued the first guidance of its kind to support people with type 1 diabetes usin

Updated on: February 19,2024

Do-It-Yourself artificial pancreas given approval by team of experts

by King's College LondonCredit: CC0 Public DomainMore than 40 healthcare professionals and legal experts have issued the first guidance of its kind to support people with type 1 diabetes usin

Updated on:February 19,2024

Research boosts case for new gene therapy to treat severe form of epilepsy

by Josh Barney,University of VirginiaCredit: CC0 Public DomainResearch from the University of Virginia School of Medicine suggests how a newly developed gene therapy can treat Dravet syndrome, a

Updated on: February 21,2024

Research boosts case for new gene therapy to treat severe form of epilepsy

by Josh Barney,University of VirginiaCredit: CC0 Public DomainResearch from the University of Virginia School of Medicine suggests how a newly developed gene therapy can treat Dravet syndrome, a

Updated on:February 21,2024

Genetic and environmental factors contribute to the overlap between depression and endocrine-metabolic disorders

by Karolinska InstitutetCredit: Unsplash/CC0 Public DomainDepression is common in individuals with endocrine-metabolic disorders and vice versa. In a study involving 2.2 million people in the Swe

Updated on: February 21,2024

Genetic and environmental factors contribute to the overlap between depression and endocrine-metabolic disorders

by Karolinska InstitutetCredit: Unsplash/CC0 Public DomainDepression is common in individuals with endocrine-metabolic disorders and vice versa. In a study involving 2.2 million people in the Swe

Updated on:February 21,2024