Study links intestinal glycan modifications to obesity and inflammation

byChiba UniversityChst4–/–mice lacking GlcNAc-6-O-sulfation of the mucinO-glycans showed significant weight gain, increased intestinal inflammation, and significantly reduced immunoglobuli

Updated on: January 18,2024

Study links intestinal glycan modifications to obesity and inflammation

byChiba UniversityChst4–/–mice lacking GlcNAc-6-O-sulfation of the mucinO-glycans showed significant weight gain, increased intestinal inflammation, and significantly reduced immunoglobuli

Updated on:January 18,2024

Research boosts case for new gene therapy to treat severe form of epilepsy

by Josh Barney,University of VirginiaCredit: CC0 Public DomainResearch from the University of Virginia School of Medicine suggests how a newly developed gene therapy can treat Dravet syndrome, a

Updated on: February 21,2024

Research boosts case for new gene therapy to treat severe form of epilepsy

by Josh Barney,University of VirginiaCredit: CC0 Public DomainResearch from the University of Virginia School of Medicine suggests how a newly developed gene therapy can treat Dravet syndrome, a

Updated on:February 21,2024

Diabetic retinopathy tied to lower vision-related quality of life

by Lori SolomonVision-related quality of life (VRQoL) declines with the presence and higher severity of diabetic retinopathy (DR), according to a review published online Feb. 1 inJAMA Ophthalmol

Updated on: March 14,2024

Diabetic retinopathy tied to lower vision-related quality of life

by Lori SolomonVision-related quality of life (VRQoL) declines with the presence and higher severity of diabetic retinopathy (DR), according to a review published online Feb. 1 inJAMA Ophthalmol

Updated on:March 14,2024

Obesity alters molecular architecture of liver cells. Repairing structure reverses metabolic disease

by Harvard School of Public HealthThe endoplasmic reticulum (ER) is white and lipid droplets appear yellow In this three-dimensional image of the interior of a diseased mouse liver cell created b

Updated on: January 31,2024

Obesity alters molecular architecture of liver cells. Repairing structure reverses metabolic disease

by Harvard School of Public HealthThe endoplasmic reticulum (ER) is white and lipid droplets appear yellow In this three-dimensional image of the interior of a diseased mouse liver cell created b

Updated on:January 31,2024

Low sodium levels linked to adverse outcomes after total joint replacement

by Wolters Kluwer HealthCredit: Pixabay/CC0 Public DomainPatients with low sodium levels before or after total knee or hip arthroplasty are more likely to experience complications and other adver

Updated on: January 31,2024

Low sodium levels linked to adverse outcomes after total joint replacement

by Wolters Kluwer HealthCredit: Pixabay/CC0 Public DomainPatients with low sodium levels before or after total knee or hip arthroplasty are more likely to experience complications and other adver

Updated on:January 31,2024

Offspring of people who were obese as teens are likely to be obese as well, study finds

by Bob Yirka , Medical XpressMean Body Mass Index (BMI) Distribution of Offspring According to Maternal and Paternal BMI Status. Analyses are based on 447,883 complete parent-offspring (of both sexes)

Updated on: July 08,2024

Offspring of people who were obese as teens are likely to be obese as well, study finds

by Bob Yirka , Medical XpressMean Body Mass Index (BMI) Distribution of Offspring According to Maternal and Paternal BMI Status. Analyses are based on 447,883 complete parent-offspring (of both sexes)

Updated on:July 08,2024

Hormone may predict ability to maintain weight loss

by University of Copenhagen"You could speculate whether the people who put on weight again simply lack the appetite-inhibiting effect which neurotensin appears to have,” says senior author S

Updated on: February 03,2024

Hormone may predict ability to maintain weight loss

by University of Copenhagen"You could speculate whether the people who put on weight again simply lack the appetite-inhibiting effect which neurotensin appears to have,” says senior author S

Updated on:February 03,2024

Indirectly influencing cancer's out-of-control cell replication

by Gunnar Bartsch,University of WürzburgDimeric structure of phosphoglycolate phosphatase. The enlarged section on the right shows the ligand-binding pocket in complex with the small molecule in

Updated on: February 05,2024

Indirectly influencing cancer's out-of-control cell replication

by Gunnar Bartsch,University of WürzburgDimeric structure of phosphoglycolate phosphatase. The enlarged section on the right shows the ligand-binding pocket in complex with the small molecule in

Updated on:February 05,2024

Genetic and environmental factors contribute to the overlap between depression and endocrine-metabolic disorders

by Karolinska InstitutetCredit: Unsplash/CC0 Public DomainDepression is common in individuals with endocrine-metabolic disorders and vice versa. In a study involving 2.2 million people in the Swe

Updated on: February 21,2024

Genetic and environmental factors contribute to the overlap between depression and endocrine-metabolic disorders

by Karolinska InstitutetCredit: Unsplash/CC0 Public DomainDepression is common in individuals with endocrine-metabolic disorders and vice versa. In a study involving 2.2 million people in the Swe

Updated on:February 21,2024

Low-cal vs. fasting diets: How does each affect the microbiome?

by Alan MozesWhen it comes to the array of different microorganisms found in the human gut, more is better: A more diverse microbiome is a healthier microbiome.Now, initial results of a small,on

Updated on: January 24,2024

Low-cal vs. fasting diets: How does each affect the microbiome?

by Alan MozesWhen it comes to the array of different microorganisms found in the human gut, more is better: A more diverse microbiome is a healthier microbiome.Now, initial results of a small,on

Updated on:January 24,2024

Metabolites may be better indicator than self-reported information for adherence to Mediterranean diet during pregnancy

by National University of SingaporeVolcano plots showing individual metabolite associated with peri-conception and first trimester alternate Mediterranean Diet (aMED) score reported at 8–13 weeks

Updated on: January 31,2024

Metabolites may be better indicator than self-reported information for adherence to Mediterranean diet during pregnancy

by National University of SingaporeVolcano plots showing individual metabolite associated with peri-conception and first trimester alternate Mediterranean Diet (aMED) score reported at 8–13 weeks

Updated on:January 31,2024

Dietary pyruvate targets cytosolic phospholipase A2 to mitigate inflammation and obesity in mice

by Higher Education PressThe mechanism of action of pyruvate by targeting cPLA2 and inhibiting cPLA2-mediated downstream signaling. Credit: Sadaf Hasan, Nabil Ghani, Xiangli Zhao, Julia Good, Amanda H

Updated on: July 25,2024

Dietary pyruvate targets cytosolic phospholipase A2 to mitigate inflammation and obesity in mice

by Higher Education PressThe mechanism of action of pyruvate by targeting cPLA2 and inhibiting cPLA2-mediated downstream signaling. Credit: Sadaf Hasan, Nabil Ghani, Xiangli Zhao, Julia Good, Amanda H

Updated on:July 25,2024