Dietary pyruvate targets cytosolic phospholipase A2 to mitigate inflammation and obesity in mice

by Higher Education PressThe mechanism of action of pyruvate by targeting cPLA2 and inhibiting cPLA2-mediated downstream signaling. Credit: Sadaf Hasan, Nabil Ghani, Xiangli Zhao, Julia Good, Amanda H

Updated on: July 25,2024

Dietary pyruvate targets cytosolic phospholipase A2 to mitigate inflammation and obesity in mice

by Higher Education PressThe mechanism of action of pyruvate by targeting cPLA2 and inhibiting cPLA2-mediated downstream signaling. Credit: Sadaf Hasan, Nabil Ghani, Xiangli Zhao, Julia Good, Amanda H

Updated on:July 25,2024

Suicidal ideation, behaviors show no increase with GLP-1 RAs for seniors with type 2 diabetes: Study

by Elana GotkineFor older adults with type 2 diabetes (T2D), use of glucagon-like peptide 1 receptor agonists (GLP-1 RAs) is not associated with a significantly increased risk for suicidal ideation an

Updated on: July 17,2024

Suicidal ideation, behaviors show no increase with GLP-1 RAs for seniors with type 2 diabetes: Study

by Elana GotkineFor older adults with type 2 diabetes (T2D), use of glucagon-like peptide 1 receptor agonists (GLP-1 RAs) is not associated with a significantly increased risk for suicidal ideation an

Updated on:July 17,2024

Obesity risk may pass from mothers to daughters

by The Endocrine SocietyCredit: CC0 Public DomainWomen with obesity may share risk for the disease with their daughters, but not their sons, according to a new study published in theJournal

Updated on: February 03,2024

Obesity risk may pass from mothers to daughters

by The Endocrine SocietyCredit: CC0 Public DomainWomen with obesity may share risk for the disease with their daughters, but not their sons, according to a new study published in theJournal

Updated on:February 03,2024

Study identifies potential new approach for treating diabetes complications

by Karolinska InstitutetHypoxia increases circulating ROS in patients with diabetes but not in control subjects without diabetes. Healthy controls (A) and subjects with type 1 diabetes (B) were e

Updated on: February 21,2024

Study identifies potential new approach for treating diabetes complications

by Karolinska InstitutetHypoxia increases circulating ROS in patients with diabetes but not in control subjects without diabetes. Healthy controls (A) and subjects with type 1 diabetes (B) were e

Updated on:February 21,2024

FDA halts sale of off-brand Ozempic and other GLP-1 drugs

Updated on: June 02,2025

FDA halts sale of off-brand Ozempic and other GLP-1 drugs

Updated on:June 02,2025

Experimental compound counters diabetic complications

by NYU Langone HealthThelarger, centrally located structure shown here is a glomerulus in a mouse kidney, which is known to be damaged by diabetes, as made evident by the scar tissue dyed p

Updated on: February 21,2024

Experimental compound counters diabetic complications

by NYU Langone HealthThelarger, centrally located structure shown here is a glomerulus in a mouse kidney, which is known to be damaged by diabetes, as made evident by the scar tissue dyed p

Updated on:February 21,2024

'Tiny but mighty' gene fragments are crucial for maintaining blood glucose levels, shows study

by Center for Genomic RegulationPancreatic islets in mice, specialized tissues that host beta cells. On the left, a healthy pancreatic islet is shown with its typical morphology with alpha cells in th

Updated on: February 19,2024

'Tiny but mighty' gene fragments are crucial for maintaining blood glucose levels, shows study

by Center for Genomic RegulationPancreatic islets in mice, specialized tissues that host beta cells. On the left, a healthy pancreatic islet is shown with its typical morphology with alpha cells in th

Updated on:February 19,2024

Ovary removal when young could raise Parkinson's risk

by Cara MurezWomen who have both of their ovaries removed before age 43 have an increased risk of developing Parkinson's disease or parkinsonism, according to a recent study.This may owe to the su

Updated on: February 21,2024

Ovary removal when young could raise Parkinson's risk

by Cara MurezWomen who have both of their ovaries removed before age 43 have an increased risk of developing Parkinson's disease or parkinsonism, according to a recent study.This may owe to the su

Updated on:February 21,2024

New connections between circadian rhythm and muscle repair identified

by Melissa Rohman,Northwestern UniversityCredit: Pixabay/CC0 Public DomainNorthwestern Medicine investigators have discovered a novel mechanism that connects circadian rhythm-controlled cellular

Updated on: February 03,2024

New connections between circadian rhythm and muscle repair identified

by Melissa Rohman,Northwestern UniversityCredit: Pixabay/CC0 Public DomainNorthwestern Medicine investigators have discovered a novel mechanism that connects circadian rhythm-controlled cellular

Updated on:February 03,2024

Antidepressants may improve outcomes in people with diabetes and depression

by The Endocrine SocietyCredit: CC0 Public DomainPeople with diabetes and depression who take antidepressants may have a lower risk of death and of serious diabetes complications, according to a

Updated on: February 05,2024

Antidepressants may improve outcomes in people with diabetes and depression

by The Endocrine SocietyCredit: CC0 Public DomainPeople with diabetes and depression who take antidepressants may have a lower risk of death and of serious diabetes complications, according to a

Updated on:February 05,2024

Clinical report addresses screening, management of congenital hypothyroidism

by Elana GotkineNewborn screening (NBS) and management of congenital hypothyroidism is addressed in a clinical report published online Dec. 19 inPediatrics.Noting that prompt diagnosis ofc

Updated on: February 05,2024

Clinical report addresses screening, management of congenital hypothyroidism

by Elana GotkineNewborn screening (NBS) and management of congenital hypothyroidism is addressed in a clinical report published online Dec. 19 inPediatrics.Noting that prompt diagnosis ofc

Updated on:February 05,2024

Active brown adipose tissue protects against 'pre-prediabetes'

by Society of Nuclear Medicine and Molecular ImagingImages showing detection and segmentation of brown adipose tissue on FDG PET in order to measure total brown adipose tissue volume. Credit:Jou

Updated on: February 05,2024

Active brown adipose tissue protects against 'pre-prediabetes'

by Society of Nuclear Medicine and Molecular ImagingImages showing detection and segmentation of brown adipose tissue on FDG PET in order to measure total brown adipose tissue volume. Credit:Jou

Updated on:February 05,2024