3-D 'mini-gut' model reflects autoimmune response to gluten in celiac patient tissue

by Massachusetts General HospitalCredit: CC0 Public DomainIn pursuit of a novel tool for the research and treatment of celiac disease, scientists at the Mucosal Immunology and Biology Research Ce

Updated on: April 02,2024

3-D 'mini-gut' model reflects autoimmune response to gluten in celiac patient tissue

by Massachusetts General HospitalCredit: CC0 Public DomainIn pursuit of a novel tool for the research and treatment of celiac disease, scientists at the Mucosal Immunology and Biology Research Ce

Updated on:April 02,2024

Novel microfluidic device models gut neuro-epithelial connections

by TranSpreadCreating enteric neuro-epithelial co-cultures in a microfluidic device. Credit:Microsystems & Nanoengineering(2023). DOI: 10.1038/s41378-023-00615-yEpithelial cells and se

Updated on: March 05,2024

Novel microfluidic device models gut neuro-epithelial connections

by TranSpreadCreating enteric neuro-epithelial co-cultures in a microfluidic device. Credit:Microsystems & Nanoengineering(2023). DOI: 10.1038/s41378-023-00615-yEpithelial cells and se

Updated on:March 05,2024

Treatment for inflammatory bowel disease doesn't always work; new study uncovers why

by Children's Hospital Los AngelesCredit: CC0 Public DomainInflammatory bowel disease (IBD) affects more than 70,000 children in the United States and the prevalence is rising. In fact, 25% o

Updated on: March 12,2024

Treatment for inflammatory bowel disease doesn't always work; new study uncovers why

by Children's Hospital Los AngelesCredit: CC0 Public DomainInflammatory bowel disease (IBD) affects more than 70,000 children in the United States and the prevalence is rising. In fact, 25% o

Updated on:March 12,2024

Study investigates potential for gut microbiome to alter drug safety and efficacy

by Princeton UniversityResearchers at Princeton created a system for evaluating how the body's gut bacteria alter the safety and efficacy of everyday drugs. The system can be used in pharmace

Updated on: April 20,2024

Study investigates potential for gut microbiome to alter drug safety and efficacy

by Princeton UniversityResearchers at Princeton created a system for evaluating how the body's gut bacteria alter the safety and efficacy of everyday drugs. The system can be used in pharmace

Updated on:April 20,2024

People with advanced bowel cancer are less likely to have participated in cancer screenings

by King's College LondonCredit: CC0 Public DomainA collaboration between a team at King's College London led by Peter Sasieni and a QMUL-based group led by Stephen Duffy collected data fr

Updated on: June 14,2024

People with advanced bowel cancer are less likely to have participated in cancer screenings

by King's College LondonCredit: CC0 Public DomainA collaboration between a team at King's College London led by Peter Sasieni and a QMUL-based group led by Stephen Duffy collected data fr

Updated on:June 14,2024

Hydrogen generated by Si-based agent attenuates inflammation in ulcerative colitis mouse model

by Osaka UniversityFig. 1. Amount of hydrogen generated per 1 g of the mouse gastrointestinal tract in the control group compared with in the mice given the silicon (Si)-based agent. Credit:&nbsp

Updated on: June 14,2024

Hydrogen generated by Si-based agent attenuates inflammation in ulcerative colitis mouse model

by Osaka UniversityFig. 1. Amount of hydrogen generated per 1 g of the mouse gastrointestinal tract in the control group compared with in the mice given the silicon (Si)-based agent. Credit:&nbsp

Updated on:June 14,2024

Microbes help orchestrate how the gut uses its genes

by Karl Leif Bates,Duke UniversityA confocal microscopy image of small villi in the small intestine shows cell nuclei in blue and absorbed dietary fat in red. Credit: John Rawls Lab, Duke Microb

Updated on: May 17,2024

Microbes help orchestrate how the gut uses its genes

by Karl Leif Bates,Duke UniversityA confocal microscopy image of small villi in the small intestine shows cell nuclei in blue and absorbed dietary fat in red. Credit: John Rawls Lab, Duke Microb

Updated on:May 17,2024

New study identifies potential therapeutic target for colonic disorders

by ElsevierNeuropilin 2 (Nrp2) expression is enriched in mouse and human colonic smooth muscle. A–C: The 8-week–old C57BL/6 mouse colon (A and B) or small intestine (C) expressing strong Nrp2 sig

Updated on: May 09,2024

New study identifies potential therapeutic target for colonic disorders

by ElsevierNeuropilin 2 (Nrp2) expression is enriched in mouse and human colonic smooth muscle. A–C: The 8-week–old C57BL/6 mouse colon (A and B) or small intestine (C) expressing strong Nrp2 sig

Updated on:May 09,2024

Risk for all-cause mortality no higher with inflammatory bowel disease

The risk for cardiovascular diseases and infections may be higher in some subgroups of Crohn disease (CD) patients, according to a study published online Oct. 14 in theJournal of Crohn's and

Updated on: April 24,2024

Risk for all-cause mortality no higher with inflammatory bowel disease

The risk for cardiovascular diseases and infections may be higher in some subgroups of Crohn disease (CD) patients, according to a study published online Oct. 14 in theJournal of Crohn's and

Updated on:April 24,2024

Possible link between Alzheimer's disease and gut microbiome found in mice

by Catherine Purse,The ConversationCredit: AI-generated imageResearchers may have found an unlikely contributor to the development ofAlzheimer's disease: the bacteria in your gut.&nbsp

Updated on: March 26,2024

Possible link between Alzheimer's disease and gut microbiome found in mice

by Catherine Purse,The ConversationCredit: AI-generated imageResearchers may have found an unlikely contributor to the development ofAlzheimer's disease: the bacteria in your gut.&nbsp

Updated on:March 26,2024

Engineered probiotic can 'sense' inflammatory bowel disease

by Olivia Dimmer,Northwestern UniversityEcN show distinct gene expression changes in response to calprotectin. (A) RNA-seq was performed on EcN that were treated with calprotectin in either mini

Updated on: June 17,2024

Engineered probiotic can 'sense' inflammatory bowel disease

by Olivia Dimmer,Northwestern UniversityEcN show distinct gene expression changes in response to calprotectin. (A) RNA-seq was performed on EcN that were treated with calprotectin in either mini

Updated on:June 17,2024

Acupuncture may aid irritable bowel syndrome with diarrhea

by Lori SolomonAcupuncture is safe and feasible for patients with irritable bowel syndrome with diarrhea (IBS-D), according to a pilot study published online Dec. 29 inJAMA Network Open.Ling-Yu

Updated on: March 12,2024

Acupuncture may aid irritable bowel syndrome with diarrhea

by Lori SolomonAcupuncture is safe and feasible for patients with irritable bowel syndrome with diarrhea (IBS-D), according to a pilot study published online Dec. 29 inJAMA Network Open.Ling-Yu

Updated on:March 12,2024