Engineers' new capsule aims to deliver drugs—and hope—to GI patients

by Rebecca Copeland,University of MarylandActuation and SMAD delivery principle. a) Capsule transits through a GI tract with inflammatory lesions and delivers the SMAD to an inflammatory site fo

Updated on: June 17,2024

Engineers' new capsule aims to deliver drugs—and hope—to GI patients

by Rebecca Copeland,University of MarylandActuation and SMAD delivery principle. a) Capsule transits through a GI tract with inflammatory lesions and delivers the SMAD to an inflammatory site fo

Updated on:June 17,2024

Smart pill could be game changer in diagnosis, treatment of bowel diseases

by Elizabeth A. Thomson,Materials Research Laboratory, Massachusetts Institute of TechnologyMIT and Boston University researchers and colleagues report a smart pill the size of a blueberry that

Updated on: March 12,2024

Smart pill could be game changer in diagnosis, treatment of bowel diseases

by Elizabeth A. Thomson,Materials Research Laboratory, Massachusetts Institute of TechnologyMIT and Boston University researchers and colleagues report a smart pill the size of a blueberry that

Updated on:March 12,2024

Study reveals colon tumor location matters for metastatic disease

by Yale Cancer Center/Smilow Cancer HospitalHuman anatomy of the gastrointestinal (GI) system; the GI system is divided in stomach, small and large intestines; the large intestine (colon) is subdivide

Updated on: April 03,2024

Study reveals colon tumor location matters for metastatic disease

by Yale Cancer Center/Smilow Cancer HospitalHuman anatomy of the gastrointestinal (GI) system; the GI system is divided in stomach, small and large intestines; the large intestine (colon) is subdivide

Updated on:April 03,2024

AGA releases largest report on safety and effectiveness of fecal microbiota transplantation

byAmerican Gastroenterological AssociationCredit: CC0 Public DomainToday, the American Gastroenterological Association (AGA) released the first results from the NIH-funded AGA Fecal Microbiota T

Updated on: February 19,2024

AGA releases largest report on safety and effectiveness of fecal microbiota transplantation

byAmerican Gastroenterological AssociationCredit: CC0 Public DomainToday, the American Gastroenterological Association (AGA) released the first results from the NIH-funded AGA Fecal Microbiota T

Updated on:February 19,2024

Research shows stimulating tuft cell production reverses intestinal inflammation

by Marissa Shapiro,Vanderbilt UniversityRestoration of the finger-like architecture of the intestine upon tuft cell stimulation in Crohn’s disease model (left) untreated, (right) treated. Arrows

Updated on: April 20,2024

Research shows stimulating tuft cell production reverses intestinal inflammation

by Marissa Shapiro,Vanderbilt UniversityRestoration of the finger-like architecture of the intestine upon tuft cell stimulation in Crohn’s disease model (left) untreated, (right) treated. Arrows

Updated on:April 20,2024

Obscure gastrointestinal bleeding: Rebleeding rates and rebleeding predictors found

by Osaka Metropolitan UniversityThe overall cumulative rebleeding rate in the five years after capsule endoscopy (CE) was as high as 41.7%. Overt obscure gastrointestinal bleeding (OGIB), anticoagulan

Updated on: March 28,2024

Obscure gastrointestinal bleeding: Rebleeding rates and rebleeding predictors found

by Osaka Metropolitan UniversityThe overall cumulative rebleeding rate in the five years after capsule endoscopy (CE) was as high as 41.7%. Overt obscure gastrointestinal bleeding (OGIB), anticoagulan

Updated on:March 28,2024

Constipation associated with increased risk of hypertension, cardiovascular events in elderly Australian patients

by La Trobe UniversitySummary of the findings. This study found that constipation was positively associated with hypertension and cardiovascular events. CI, confidence interval; OR, odds ratio. T

Updated on: March 26,2024

Constipation associated with increased risk of hypertension, cardiovascular events in elderly Australian patients

by La Trobe UniversitySummary of the findings. This study found that constipation was positively associated with hypertension and cardiovascular events. CI, confidence interval; OR, odds ratio. T

Updated on:March 26,2024

Small intestine found to adapt its size according to nutrient intake

by University of CopenhagenThe activin signaling pathway control turnover of intestinal cells. Credit:Nature Communications(2024). DOI: 10.1038/s41467-023-44553-9Resizing of the intes

Updated on: March 05,2024

Small intestine found to adapt its size according to nutrient intake

by University of CopenhagenThe activin signaling pathway control turnover of intestinal cells. Credit:Nature Communications(2024). DOI: 10.1038/s41467-023-44553-9Resizing of the intes

Updated on:March 05,2024

Human norovirus GII.4 exploits unexpected entry mechanism to cause gastroenteritis

by Baylor College of MedicineGII.4 capsid protein elicits acidification and endocytosis in HIEs.aViral replication at 24 h (black dots) compared to bound virus at 1 h (blue dots) and

Updated on: May 26,2024

Human norovirus GII.4 exploits unexpected entry mechanism to cause gastroenteritis

by Baylor College of MedicineGII.4 capsid protein elicits acidification and endocytosis in HIEs.aViral replication at 24 h (black dots) compared to bound virus at 1 h (blue dots) and

Updated on:May 26,2024

Metabolic dysfunction-associated fatty liver disease is associated with greater impairment of lung function: Study

by Xia & He Publishing Inc.Flowchart of subject recruitment. Credit:Journal of Clinical and Translational Hepatology(2022). DOI: 10.14218/JCTH.2021.00306Recent research, which involved

Updated on: January 24,2024

Metabolic dysfunction-associated fatty liver disease is associated with greater impairment of lung function: Study

by Xia & He Publishing Inc.Flowchart of subject recruitment. Credit:Journal of Clinical and Translational Hepatology(2022). DOI: 10.14218/JCTH.2021.00306Recent research, which involved

Updated on:January 24,2024

New drug target to treat pain from visceral organs

by Thomas Jefferson UniversityGraphical abstract. Credit:Journal of Clinical Investigation(2022). DOI: 10.1172/JCI165578An approved drug for chronic constipation also relieves the pai

Updated on: March 12,2024

New drug target to treat pain from visceral organs

by Thomas Jefferson UniversityGraphical abstract. Credit:Journal of Clinical Investigation(2022). DOI: 10.1172/JCI165578An approved drug for chronic constipation also relieves the pai

Updated on:March 12,2024

Age and aging have critical effects on the gut microbiome

by Cedars-Sinai Medical CenterA new study led by Ruchi Mathur, MD, found that aging produces significant changes in the microbiome of the human small intestine. Credit: Cedars-SinaiResearchers at

Updated on: May 28,2024

Age and aging have critical effects on the gut microbiome

by Cedars-Sinai Medical CenterA new study led by Ruchi Mathur, MD, found that aging produces significant changes in the microbiome of the human small intestine. Credit: Cedars-SinaiResearchers at

Updated on:May 28,2024