Study reveals immune-modulatory mechanism of lurbinectedin in small-cell lung cancer

byThe Mount Sinai HospitalLurbinectedin augments the anti-tumor immune response of PD-L1 blockade in immunocompetent SCLC models. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.x

Updated on: January 21,2025 0

Study reveals immune-modulatory mechanism of lurbinectedin in small-cell lung cancer

byThe Mount Sinai HospitalLurbinectedin augments the anti-tumor immune response of PD-L1 blockade in immunocompetent SCLC models. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.x

Updated on:January 21,2025 0

CRISPR study silences gene mutations that drive aggressive cancers

byPeter MacCallum Cancer CentreMolecular principles of CRISPR-Cas13 mismatch intolerance enable selective silencing of point-mutated oncogenic RNA with single-base precision. Credit:Scienc

Updated on: January 21,2025 0

CRISPR study silences gene mutations that drive aggressive cancers

byPeter MacCallum Cancer CentreMolecular principles of CRISPR-Cas13 mismatch intolerance enable selective silencing of point-mutated oncogenic RNA with single-base precision. Credit:Scienc

Updated on:January 21,2025 0

Digital twin research finds colon cancer cells can be reverted to normal cells

byThe Korea Advanced Institute of Science and Technology (KAIST)igure 6. Schematic diagram of the research results. Professor Kwang-Hyun Cho's research team developed a source technology to

Updated on: January 21,2025 0

Digital twin research finds colon cancer cells can be reverted to normal cells

byThe Korea Advanced Institute of Science and Technology (KAIST)igure 6. Schematic diagram of the research results. Professor Kwang-Hyun Cho's research team developed a source technology to

Updated on:January 21,2025 0

Machine learning uncovers three osteosarcoma subtypes for targeted treatment

byUniversity of East AngliaLatent process decomposition model optimization, subtype assignment and clinical outcome. Credit:Briefings in Bioinformatics(2024). DOI: 10.1093/bib/bbae66

Updated on: January 21,2025 0

Machine learning uncovers three osteosarcoma subtypes for targeted treatment

byUniversity of East AngliaLatent process decomposition model optimization, subtype assignment and clinical outcome. Credit:Briefings in Bioinformatics(2024). DOI: 10.1093/bib/bbae66

Updated on:January 21,2025 0

Advanced cancer models could help personalize lymphoma treatments

Advanced cancer models could help personalize lymphoma treatmentsby Nik Papageorgiou,Ecole Polytechnique Federale de LausanneLymphomoid spiral. Credit: Albert Santamaria-MartinezScientists at EP

Updated on: January 20,2025 0

Advanced cancer models could help personalize lymphoma treatments

Advanced cancer models could help personalize lymphoma treatmentsby Nik Papageorgiou,Ecole Polytechnique Federale de LausanneLymphomoid spiral. Credit: Albert Santamaria-MartinezScientists at EP

Updated on:January 20,2025 0

Researchers find new way to 'starve' prostate cancer tumors at the cellular level

byIndiana UniversityKirk Staschke and Noah Sommers, a Ph.D. student at the IU School of Medicine, at the microscope. Credit: Kirk StaschkeNew research by a team of Indiana University School of M

Updated on: January 20,2025 0

Researchers find new way to 'starve' prostate cancer tumors at the cellular level

byIndiana UniversityKirk Staschke and Noah Sommers, a Ph.D. student at the IU School of Medicine, at the microscope. Credit: Kirk StaschkeNew research by a team of Indiana University School of M

Updated on:January 20,2025 0

Could a pill replace gene therapy for sickle cell disease? Research uncovers potential path to small-molecule drug

by Nancy Fliesler,Children's Hospital BostonNew work suggests ways to target the BCL11A protein with drugs, enabling patients with sickle cell disease to produce non-sickling fetal hemoglobi

Updated on: January 17,2025 0

Could a pill replace gene therapy for sickle cell disease? Research uncovers potential path to small-molecule drug

by Nancy Fliesler,Children's Hospital BostonNew work suggests ways to target the BCL11A protein with drugs, enabling patients with sickle cell disease to produce non-sickling fetal hemoglobi

Updated on:January 17,2025 0

Reducing dose of popular blood thinners may limit risk of future bleeding, study finds

byUniversity of MichiganCredit: Pixabay/CC0 Public DomainFor people taking popular blood thinners after having a blood clot, a reduced dose may limit the future risk of bleeding as well as hospi

Updated on: January 17,2025 0

Reducing dose of popular blood thinners may limit risk of future bleeding, study finds

byUniversity of MichiganCredit: Pixabay/CC0 Public DomainFor people taking popular blood thinners after having a blood clot, a reduced dose may limit the future risk of bleeding as well as hospi

Updated on:January 17,2025 0

Innovative red blood cell shape test promises better blood storage and transfusions

Innovative red blood cell shape test promises better blood storage and transfusionsbyUniversity of OxfordCredit: Pixabay/CC0 Public DomainScientists have developed a way of assessing the ability

Updated on: January 06,2025 0

Innovative red blood cell shape test promises better blood storage and transfusions

Innovative red blood cell shape test promises better blood storage and transfusionsbyUniversity of OxfordCredit: Pixabay/CC0 Public DomainScientists have developed a way of assessing the ability

Updated on:January 06,2025 0

Auto hematopoietic cell transplant not beneficial for mantle cell lymphoma with undetectable residual disease

by Elana GotkineAutologous hematopoietic cell transplant (auto-HCT) is not beneficial for patients with mantle cell lymphoma (MCL) in first complete remission (CR) with undetectable minimal residual d

Updated on: December 21,2024 0

Auto hematopoietic cell transplant not beneficial for mantle cell lymphoma with undetectable residual disease

by Elana GotkineAutologous hematopoietic cell transplant (auto-HCT) is not beneficial for patients with mantle cell lymphoma (MCL) in first complete remission (CR) with undetectable minimal residual d

Updated on:December 21,2024 0

Scientists expose cells driving aggressive tumor growth

byUniversity College LondonSPRINTER identifies tumor clone proliferation heterogeneity in patient CRUKP9145 with NSCLC. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01989-zT

Updated on: December 21,2024 0

Scientists expose cells driving aggressive tumor growth

byUniversity College LondonSPRINTER identifies tumor clone proliferation heterogeneity in patient CRUKP9145 with NSCLC. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01989-zT

Updated on:December 21,2024 0

Annual report reveals more cancers are being treated with personalized therapies before surgery

byAmerican College of SurgeonsWhat to know about breast cancer according to the National Cancer Database. Credit: American College of SurgeonsBreast, bladder, and pancreatic cancers are increasi

Updated on: December 21,2024 0

Annual report reveals more cancers are being treated with personalized therapies before surgery

byAmerican College of SurgeonsWhat to know about breast cancer according to the National Cancer Database. Credit: American College of SurgeonsBreast, bladder, and pancreatic cancers are increasi

Updated on:December 21,2024 0