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Hepatobiliary&Pancreas Surgery
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Alcohol-related liver disease: Mechanism could form basis for development of new therapies

Alcohol-related liver disease: Mechanism could form basis for development of new therapies

by Medical University of ViennaCredit: AI-generated imageAlcohol-related liver disease is among the most common causes of morbidity and mortality worldwide. Due to an incomplete understanding of

Alcohol-related liver disease: Mechanism could form basis for development of new therapies

by Medical University of ViennaCredit: AI-generated imageAlcohol-related liver disease is among the most common causes of morbidity and mortality worldwide. Due to an incomplete understanding of
Study shows seladelpar beneficial for patients with primary biliary cholangitis

Study shows seladelpar beneficial for patients with primary biliary cholangitis

by Elana GotkineFor patients with primary biliary cholangitis, more receiving the peroxisome proliferator-activated receptor delta (PPARδ) agonist seladelpar have a biochemical response and alkaline p

Study shows seladelpar beneficial for patients with primary biliary cholangitis

by Elana GotkineFor patients with primary biliary cholangitis, more receiving the peroxisome proliferator-activated receptor delta (PPARδ) agonist seladelpar have a biochemical response and alkaline p
Scientists find omega-3 lysolipids may prevent fatty liver disease

Scientists find omega-3 lysolipids may prevent fatty liver disease

by Duke-NUS Medical SchoolDetection of the lysolipid transporter Mfsd2a in hepatocytes, stained green, in proximity to a bile duct, stained magenta. Credit: Chin Cheen FeiLong-running research by

Scientists find omega-3 lysolipids may prevent fatty liver disease

by Duke-NUS Medical SchoolDetection of the lysolipid transporter Mfsd2a in hepatocytes, stained green, in proximity to a bile duct, stained magenta. Credit: Chin Cheen FeiLong-running research by
Popular diabetes drug may also reduce the risk of severe liver disease

Popular diabetes drug may also reduce the risk of severe liver disease

by Karolinska InstitutetCredit: Pixabay/CC0 Public DomainOzempic and other GLP1 agonists are associated with a reduced risk of developing cirrhosis and liver cancer in people with type 2 diabetes

Popular diabetes drug may also reduce the risk of severe liver disease

by Karolinska InstitutetCredit: Pixabay/CC0 Public DomainOzempic and other GLP1 agonists are associated with a reduced risk of developing cirrhosis and liver cancer in people with type 2 diabetes
Using social determinants of health to guide liver disease screening

Using social determinants of health to guide liver disease screening

by Ariana Baldassano,Rush University Medical CenterCredit:JHEP Reports(2023). DOI: 10.1016/j.jhepr.2023.100696Black people face a higher risk of developing severe liver fibrosis, but

Using social determinants of health to guide liver disease screening

by Ariana Baldassano,Rush University Medical CenterCredit:JHEP Reports(2023). DOI: 10.1016/j.jhepr.2023.100696Black people face a higher risk of developing severe liver fibrosis, but
New standards to quantify hepatitis B virus reservoirs in liver cells

New standards to quantify hepatitis B virus reservoirs in liver cells

by Nicola Wittekindt, Deutsches Zentrum für InfektionsforschungThe effect of different DNA extraction methods on cccDNA quantification by qPCR and SB in HBV-infected USG mouse liver tissue. (A) Schema

New standards to quantify hepatitis B virus reservoirs in liver cells

by Nicola Wittekindt, Deutsches Zentrum für InfektionsforschungThe effect of different DNA extraction methods on cccDNA quantification by qPCR and SB in HBV-infected USG mouse liver tissue. (A) Schema
Maddening itch of liver disease comes from a surprising source

Maddening itch of liver disease comes from a surprising source

by Duke University School of NursingExcess lipids produced by liver failure signal an itching sensation directly to the skin cells, through a receptor called TRPV4 and a microRNA. Credit: Wolfgan

Maddening itch of liver disease comes from a surprising source

by Duke University School of NursingExcess lipids produced by liver failure signal an itching sensation directly to the skin cells, through a receptor called TRPV4 and a microRNA. Credit: Wolfgan
Two-organ chip developed to answer fatty liver questions

Two-organ chip developed to answer fatty liver questions

by Kyoto UniversityThe interaction between the small intestine and the liver of patients with non-alcoholic fatty liver disease (NAFLD) has been reproduced on a small chip. Credit: Mindy Takamiya

Two-organ chip developed to answer fatty liver questions

by Kyoto UniversityThe interaction between the small intestine and the liver of patients with non-alcoholic fatty liver disease (NAFLD) has been reproduced on a small chip. Credit: Mindy Takamiya
Immune therapies against chronic hepatitis B

Immune therapies against chronic hepatitis B

by Ehime UniversityTwo main types of immune therapies have been employed to treat chronic hepatitis B during the last 4 decades. However, it seems that HBV-antigen-specific immune therapy may be safe

Immune therapies against chronic hepatitis B

by Ehime UniversityTwo main types of immune therapies have been employed to treat chronic hepatitis B during the last 4 decades. However, it seems that HBV-antigen-specific immune therapy may be safe
Gut microbiota harnessed as tool to diagnose diseases, promising results for fatty liver diagnosis

Gut microbiota harnessed as tool to diagnose diseases, promising results for fatty liver diagnosis

by University of JyväskyläThe diversity of the gut microbiota in the low (n = 25) and high (n = 37) liver fat groups. (A) Shannon index, a measure of alpha-diversity indicating species diversity.

Gut microbiota harnessed as tool to diagnose diseases, promising results for fatty liver diagnosis

by University of JyväskyläThe diversity of the gut microbiota in the low (n = 25) and high (n = 37) liver fat groups. (A) Shannon index, a measure of alpha-diversity indicating species diversity.
Assessing the mechanisms for liver fibrosis

Assessing the mechanisms for liver fibrosis

by First Hospital of Jilin UniversityHepatocyte-mediated activation of HSC, the innate and adaptive immune activation in the metabolic syndrome. Soluble mediators are in red. Credit: Wajahat MehalChro

Assessing the mechanisms for liver fibrosis

by First Hospital of Jilin UniversityHepatocyte-mediated activation of HSC, the innate and adaptive immune activation in the metabolic syndrome. Soluble mediators are in red. Credit: Wajahat MehalChro