Proof-of-concept study demonstrates novel strategy to develop liver-targeting chimeras for disease treatment

by Liu Jia,Chinese Academy of SciencesCredit:Journal of Controlled Release(2024). DOI: 10.1016/j.jconrel.2024.08.044Liver cancer ranks as the fourth most common cancer and the second

Updated on: September 15,2024

Proof-of-concept study demonstrates novel strategy to develop liver-targeting chimeras for disease treatment

by Liu Jia,Chinese Academy of SciencesCredit:Journal of Controlled Release(2024). DOI: 10.1016/j.jconrel.2024.08.044Liver cancer ranks as the fourth most common cancer and the second

Updated on:September 15,2024

Study reveals genetic drivers of metabolic dysfunction-associated steatotic liver disease

by Becky Ham,Translational Genomics Research InstituteOverview of the study design. Credit:Life Science Alliance(2024). DOI: 10.26508/lsa.202302517In the largest study of its kind, r

Updated on: April 06,2024

Study reveals genetic drivers of metabolic dysfunction-associated steatotic liver disease

by Becky Ham,Translational Genomics Research InstituteOverview of the study design. Credit:Life Science Alliance(2024). DOI: 10.26508/lsa.202302517In the largest study of its kind, r

Updated on:April 06,2024

Maddening itch of liver disease comes from a surprising source

by Duke University School of NursingExcess lipids produced by liver failure signal an itching sensation directly to the skin cells, through a receptor called TRPV4 and a microRNA. Credit: Wolfgan

Updated on: May 29,2024

Maddening itch of liver disease comes from a surprising source

by Duke University School of NursingExcess lipids produced by liver failure signal an itching sensation directly to the skin cells, through a receptor called TRPV4 and a microRNA. Credit: Wolfgan

Updated on:May 29,2024

The role of non-parenchymal cells in liver metabolism and disease

Updated on: July 20,2024

The role of non-parenchymal cells in liver metabolism and disease

Updated on:July 20,2024

Nature:Pluripotent stem cells build liver-like organs to help treat liver disease

Updated on: April 22,2025

Nature:Pluripotent stem cells build liver-like organs to help treat liver disease

Updated on:April 22,2025

A novel malaria vaccine vector that targets the liver

by Kanazawa UniversityThe IVIS imaging results for the livers collected from mice on day 8 or day 224 post-administration of AAV-Luc showed that systemic administration of AAV8 induced ~24–43 tim

Updated on: March 25,2024

A novel malaria vaccine vector that targets the liver

by Kanazawa UniversityThe IVIS imaging results for the livers collected from mice on day 8 or day 224 post-administration of AAV-Luc showed that systemic administration of AAV8 induced ~24–43 tim

Updated on:March 25,2024

YKT6 gene variants cause a new neurological disorder, finds study

byTexas Children's HospitalCredit: Unsplash/CC0 Public DomainA recent collaborative study has discovered rare variants in the YKT6 gene as the cause of a new neurological disorder characteri

Updated on: April 06,2024

YKT6 gene variants cause a new neurological disorder, finds study

byTexas Children's HospitalCredit: Unsplash/CC0 Public DomainA recent collaborative study has discovered rare variants in the YKT6 gene as the cause of a new neurological disorder characteri

Updated on:April 06,2024

New algorithm can predict advanced liver disease

(HealthDay)—A model that uses routine primary care data can predict the risk for advanced liver disease, according to a study published online Feb. 11 inBMJ Open.Theresa Hydes, Ph.D., from the U

Updated on: April 29,2024

New algorithm can predict advanced liver disease

(HealthDay)—A model that uses routine primary care data can predict the risk for advanced liver disease, according to a study published online Feb. 11 inBMJ Open.Theresa Hydes, Ph.D., from the U

Updated on:April 29,2024

Providing clinicians with an AI sidekick to help to identify cirrhosis

by Sarah Dooley,Medical University of South CarolinaFuturistic illustration of a liver, suggesting use of artificial intelligence to improve liver health. Credit: Jihad Obeid, Medical University

Updated on: May 17,2024

Providing clinicians with an AI sidekick to help to identify cirrhosis

by Sarah Dooley,Medical University of South CarolinaFuturistic illustration of a liver, suggesting use of artificial intelligence to improve liver health. Credit: Jihad Obeid, Medical University

Updated on:May 17,2024

Inflammation discovery advances the fight against chronic liver disease

by QIMR Berghofer Medical Research InstituteInhibition of late endosome/lysosome function on ICAM-1 distribution in FTH-treated rat HSCs. Credit:Science Signaling(2024). DOI: 10.1126/scisi

Updated on: April 27,2024

Inflammation discovery advances the fight against chronic liver disease

by QIMR Berghofer Medical Research InstituteInhibition of late endosome/lysosome function on ICAM-1 distribution in FTH-treated rat HSCs. Credit:Science Signaling(2024). DOI: 10.1126/scisi

Updated on:April 27,2024

Researchers identify a potential therapeutic target against cirrhosis and liver inflammation

by University of BarcelonaA new study by a team of the University of Barcelona could promote the design of drugs to treat these pathologies. Credit: University of BarcelonaThe RNF41 protein could

Updated on: January 29,2024

Researchers identify a potential therapeutic target against cirrhosis and liver inflammation

by University of BarcelonaA new study by a team of the University of Barcelona could promote the design of drugs to treat these pathologies. Credit: University of BarcelonaThe RNF41 protein could

Updated on:January 29,2024

Cytoglobin: Key player in preventing liver disease

by Osaka City University6His tagged recombinant human CYGB (His-CYGB) was endocytosed into the HSCs via Clathrin-mediated pathway, scavenged ROS, such as O2- and OH-, and induced IFN-β secretion media

Updated on: May 09,2024

Cytoglobin: Key player in preventing liver disease

by Osaka City University6His tagged recombinant human CYGB (His-CYGB) was endocytosed into the HSCs via Clathrin-mediated pathway, scavenged ROS, such as O2- and OH-, and induced IFN-β secretion media

Updated on:May 09,2024