ATP from sensory neuron-interneuron crosstalk is key to spreading inflammation in rheumatoid arthritis

by Hokkaido UniversityThe inflammation signal (IL-6 amplifier) in the affected joint (L) causes the secretion of ATP that transmits a signal through the spinal cord (DRG, L5), which in turn trigg

Updated on: June 06,2024 4

ATP from sensory neuron-interneuron crosstalk is key to spreading inflammation in rheumatoid arthritis

by Hokkaido UniversityThe inflammation signal (IL-6 amplifier) in the affected joint (L) causes the secretion of ATP that transmits a signal through the spinal cord (DRG, L5), which in turn trigg

Updated on:June 06,2024 4

How do I know if I need a cortisone shot?

by Carrie MacMillan,Yale UniversityCredit: Unsplash/CC0 Public DomainIf you're an athlete prone to overuse injuries or if you have a chronic condition like arthritis, chances are you've

Updated on: June 06,2024 6

How do I know if I need a cortisone shot?

by Carrie MacMillan,Yale UniversityCredit: Unsplash/CC0 Public DomainIf you're an athlete prone to overuse injuries or if you have a chronic condition like arthritis, chances are you've

Updated on:June 06,2024 6

Study finds lower risk of severe infection and hospitalization with belimumab compared to oral immunosuppressants

by American College of RheumatologyComparative Risk of Severe Infection and Hospitalizations for Severe Infections with Belimumab versus Oral Immunosuppressants. Hazard ratios and 95% confidence

Updated on: June 06,2024 3

Study finds lower risk of severe infection and hospitalization with belimumab compared to oral immunosuppressants

by American College of RheumatologyComparative Risk of Severe Infection and Hospitalizations for Severe Infections with Belimumab versus Oral Immunosuppressants. Hazard ratios and 95% confidence

Updated on:June 06,2024 3

Passive smoking linked to increased risk of rheumatoid arthritis

Passive smoking during childhood and/or adulthood is associated with increased risk of rheumatoid arthritis (RA), according to a study recently published inRMD Open.Yann Nguyen, M.D., M.P.H., fr

Updated on: June 06,2024 6

Passive smoking linked to increased risk of rheumatoid arthritis

Passive smoking during childhood and/or adulthood is associated with increased risk of rheumatoid arthritis (RA), according to a study recently published inRMD Open.Yann Nguyen, M.D., M.P.H., fr

Updated on:June 06,2024 6

Oral deucravacitinib benefits patients with lupus

by WileyCredit: CC0 Public DomainTyrosine kinases are enzymes that play central roles in signaling by cytokines involved in the pathogenesis of autoimmune diseases, including lupus. A recent phas

Updated on: June 06,2024 5

Oral deucravacitinib benefits patients with lupus

by WileyCredit: CC0 Public DomainTyrosine kinases are enzymes that play central roles in signaling by cytokines involved in the pathogenesis of autoimmune diseases, including lupus. A recent phas

Updated on:June 06,2024 5

Gene variant links trigger finger and carpal tunnel syndrome

by University of OxfordAssociation between trigger finger and carpal tunnel syndrome. Data from UK Biobank. (A) Overlap between trigger finger and carpal tunnel syndrome in UK Biobank, annotated

Updated on: June 06,2024 6

Gene variant links trigger finger and carpal tunnel syndrome

by University of OxfordAssociation between trigger finger and carpal tunnel syndrome. Data from UK Biobank. (A) Overlap between trigger finger and carpal tunnel syndrome in UK Biobank, annotated

Updated on:June 06,2024 6

Numerous jobs linked to increased risk of knee reconstruction

by University of SydneyExercises to avoid and treat osteoarthritis. Credit: Institute of Bone and Joint Research, University of SydneyKnee replacements are a huge burden on society and individual

Updated on: June 06,2024 3

Numerous jobs linked to increased risk of knee reconstruction

by University of SydneyExercises to avoid and treat osteoarthritis. Credit: Institute of Bone and Joint Research, University of SydneyKnee replacements are a huge burden on society and individual

Updated on:June 06,2024 3

Researchers identify new arthritis severity gene

by The Mount Sinai HospitalCredit: CC0 Public DomainA new gene associated with disease severity in models of rheumatoid arthritis has been identified by researchers at the Icahn School of Medicin

Updated on: June 06,2024 3

Researchers identify new arthritis severity gene

by The Mount Sinai HospitalCredit: CC0 Public DomainA new gene associated with disease severity in models of rheumatoid arthritis has been identified by researchers at the Icahn School of Medicin

Updated on:June 06,2024 3

How to talk to your doctor about arthritis pain

Chronic pain can be excruciating, debilitating and hard to describe.Yet the best way to get the right treatment for the exactpainyou're experiencing is to put those symptoms into words

Updated on: June 06,2024 7

How to talk to your doctor about arthritis pain

Chronic pain can be excruciating, debilitating and hard to describe.Yet the best way to get the right treatment for the exactpainyou're experiencing is to put those symptoms into words

Updated on:June 06,2024 7

Scientists identify reversible molecular defect underlying rheumatoid arthritis

by Bruce Goldman,Stanford University Medical CenterScanning electron micrograph of human T lymphocyte or T cell. Credit: NIAID/NIHIn rheumatoid arthritis, immune cells called helper T cells beha

Updated on: June 06,2024 5

Scientists identify reversible molecular defect underlying rheumatoid arthritis

by Bruce Goldman,Stanford University Medical CenterScanning electron micrograph of human T lymphocyte or T cell. Credit: NIAID/NIHIn rheumatoid arthritis, immune cells called helper T cells beha

Updated on:June 06,2024 5

New research identifies injury-induced molecular changes in chondrocytes, at single-cell level

by Anne M Stark,Lawrence Livermore National LaboratoryGene expression in mouse knee joint chondrocytes was analyzed using single-cell RNA sequencing, which identified nine chondrocyte subpopulat

Updated on: June 06,2024 8

New research identifies injury-induced molecular changes in chondrocytes, at single-cell level

by Anne M Stark,Lawrence Livermore National LaboratoryGene expression in mouse knee joint chondrocytes was analyzed using single-cell RNA sequencing, which identified nine chondrocyte subpopulat

Updated on:June 06,2024 8

Running, even in excess, doesn't lead to more osteoarthritis and hip replacements

by Dan Krotz,Lawrence Berkeley National LaboratoryCredit: Berkeley Lab photographer Roy Kaltschmidt(Medical Xpress)—Need another reason to dust off those running shoes in the back of the closet?

Updated on: June 06,2024 5

Running, even in excess, doesn't lead to more osteoarthritis and hip replacements

by Dan Krotz,Lawrence Berkeley National LaboratoryCredit: Berkeley Lab photographer Roy Kaltschmidt(Medical Xpress)—Need another reason to dust off those running shoes in the back of the closet?

Updated on:June 06,2024 5