New insight into when CAR T is effective against childhood leukemia

by University College LondonA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/Wikimedia/CC BY-SA 3.0Scientists an

Updated on: April 08,2024 11

New insight into when CAR T is effective against childhood leukemia

by University College LondonA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/Wikimedia/CC BY-SA 3.0Scientists an

Updated on:April 08,2024 11

How mutation of the APC gene disrupts lymphocyte migration in colon cancer

by Pasteur InstituteMigrating human T lymphocytes revealing a broad protrusion at the leading edge and long adhesive protrusions at the rear. Image obtained by confocal fluorescence microscopy: f

Updated on: April 08,2024 19

How mutation of the APC gene disrupts lymphocyte migration in colon cancer

by Pasteur InstituteMigrating human T lymphocytes revealing a broad protrusion at the leading edge and long adhesive protrusions at the rear. Image obtained by confocal fluorescence microscopy: f

Updated on:April 08,2024 19

B cells gone bad could be the culprit in rheumatoid arthritis

by Laurie Fickman,University of HoustonBiomolecular researcher Navin Varadarajan anticipates that his data will serve as a foundation for investigating multiple hypotheses on the roles of B cell

Updated on: April 08,2024 14

B cells gone bad could be the culprit in rheumatoid arthritis

by Laurie Fickman,University of HoustonBiomolecular researcher Navin Varadarajan anticipates that his data will serve as a foundation for investigating multiple hypotheses on the roles of B cell

Updated on:April 08,2024 14

B cells linked to immunotherapy for melanoma

by European Molecular Biology LaboratoryUsing multiplex-immunostaining to characterise B cells. Credit: Christine WagnerResearchers at EMBL's European Bioinformatics Institute and the Medical

Updated on: April 08,2024 19

B cells linked to immunotherapy for melanoma

by European Molecular Biology LaboratoryUsing multiplex-immunostaining to characterise B cells. Credit: Christine WagnerResearchers at EMBL's European Bioinformatics Institute and the Medical

Updated on:April 08,2024 19

How B cells are programmed early in life can impact long-term immune health

by Lund UniversityGraphical abstract. Credit:Immunity(2022). DOI: 10.1016/j.immuni.2022.08.018B cells and the antibodies they produce play an important role in our immune system, prot

Updated on: April 08,2024 17

How B cells are programmed early in life can impact long-term immune health

by Lund UniversityGraphical abstract. Credit:Immunity(2022). DOI: 10.1016/j.immuni.2022.08.018B cells and the antibodies they produce play an important role in our immune system, prot

Updated on:April 08,2024 17

CAR T therapy shows long-lasting remissions in non-hodgkin lymphoma

by Perelman School of Medicine at the University of PennsylvaniaCredit: Unsplash/CC0 Public DomainA significant number of non-Hodgkin lymphoma (NHL) patients in a Penn Medicine-initiated clinical

Updated on: April 08,2024 20

CAR T therapy shows long-lasting remissions in non-hodgkin lymphoma

by Perelman School of Medicine at the University of PennsylvaniaCredit: Unsplash/CC0 Public DomainA significant number of non-Hodgkin lymphoma (NHL) patients in a Penn Medicine-initiated clinical

Updated on:April 08,2024 20

Guidance for coronary patients with ASA/NSAID sensitivity

(HealthDay)—In patients with stable chronic ischemic heart disease (CIHD) and histories of nonsevere hypersensitivity reactions to acetylsalicylic acid (ASA)/nonsteroidal anti-inflammatory drugs (NSAI

Updated on: April 08,2024 19

Guidance for coronary patients with ASA/NSAID sensitivity

(HealthDay)—In patients with stable chronic ischemic heart disease (CIHD) and histories of nonsevere hypersensitivity reactions to acetylsalicylic acid (ASA)/nonsteroidal anti-inflammatory drugs (NSAI

Updated on:April 08,2024 19

ATP-hydrolyzing ectoenzyme E-NTPD8 attenuates colitis

by Osaka UniversityE-NTPD8 in colonic epithelial cells maintains gut homeostasis through the hydrolysis of luminal ATP produced by commensal bacteria (left). An increased level of luminal ATP cau

Updated on: April 08,2024 19

ATP-hydrolyzing ectoenzyme E-NTPD8 attenuates colitis

by Osaka UniversityE-NTPD8 in colonic epithelial cells maintains gut homeostasis through the hydrolysis of luminal ATP produced by commensal bacteria (left). An increased level of luminal ATP cau

Updated on:April 08,2024 19

AID/APOBECs among important factors in body's defence against SARS-CoV-2

by Johannes Angerer,Medical University of ViennaCredit: Unsplash/CC0 Public DomainTogether with their multifaceted action mechanisms, activation-induced cytidine deaminase (AID) and so-called AP

Updated on: April 08,2024 16

AID/APOBECs among important factors in body's defence against SARS-CoV-2

by Johannes Angerer,Medical University of ViennaCredit: Unsplash/CC0 Public DomainTogether with their multifaceted action mechanisms, activation-induced cytidine deaminase (AID) and so-called AP

Updated on:April 08,2024 16

Autoimmune diseases in ALS patients linked to genetic mutation

by Sarah Lichtman,Cedars-Sinai Medical CenterRobert Baloh, MD, PhD, at work in his laboratory. Credit: Cedars-SinaiA study published today in the journalNaturecould help explain why

Updated on: April 08,2024 20

Autoimmune diseases in ALS patients linked to genetic mutation

by Sarah Lichtman,Cedars-Sinai Medical CenterRobert Baloh, MD, PhD, at work in his laboratory. Credit: Cedars-SinaiA study published today in the journalNaturecould help explain why

Updated on:April 08,2024 20

GABA released by B-cells blunts the immune response to tumors

by RIKENFig. 1: Metabolic remodeling of immunized LNs and B cell-dependent GABA production. a–e, Mice were injected in the foot pad with OVA + CFA, and iLNs and cLNs were collected for metabolite

Updated on: April 08,2024 15

GABA released by B-cells blunts the immune response to tumors

by RIKENFig. 1: Metabolic remodeling of immunized LNs and B cell-dependent GABA production. a–e, Mice were injected in the foot pad with OVA + CFA, and iLNs and cLNs were collected for metabolite

Updated on:April 08,2024 15

Higher incidence of edema with bacteriuria in C1-INH-HAE

(HealthDay)—For patients with hereditary angioedema due to C1-inhibitor deficiency (C1-INH-HAE), those with bacteriuria have a higher number of edematous attacks, according to a study published online

Updated on: April 08,2024 12

Higher incidence of edema with bacteriuria in C1-INH-HAE

(HealthDay)—For patients with hereditary angioedema due to C1-inhibitor deficiency (C1-INH-HAE), those with bacteriuria have a higher number of edematous attacks, according to a study published online

Updated on:April 08,2024 12