RNA proofreading mistakes drive group of autoimmune diseases

by The Scripps Research InstituteScripps Research Professor Patrick Griffin, PhD, of Jupiter, Florida, co-chairman of the Department of Molecular Medicine, used hydrogen-deuterium exchange mass s

Updated on: April 22,2024 14

RNA proofreading mistakes drive group of autoimmune diseases

by The Scripps Research InstituteScripps Research Professor Patrick Griffin, PhD, of Jupiter, Florida, co-chairman of the Department of Molecular Medicine, used hydrogen-deuterium exchange mass s

Updated on:April 22,2024 14

SARS-CoV-2 variant B.1.617 attacks immune system

by The German Primate CenterThe spike protein on the surface of SARS-CoV-2 virions mediates entry into target cells. It Is the main target for neutralizing antibodies that are produced following

Updated on: April 22,2024 20

SARS-CoV-2 variant B.1.617 attacks immune system

by The German Primate CenterThe spike protein on the surface of SARS-CoV-2 virions mediates entry into target cells. It Is the main target for neutralizing antibodies that are produced following

Updated on:April 22,2024 20

SARS-CoV-2 disrupts timing of immune response

by Charité - Universitätsmedizin BerlinAssay to detect the biochemical messenger TGFβ (COVID-19 research). Credit: Charité | Arne SattlerOnce an infection is under control, the body normally uses

Updated on: April 22,2024 17

SARS-CoV-2 disrupts timing of immune response

by Charité - Universitätsmedizin BerlinAssay to detect the biochemical messenger TGFβ (COVID-19 research). Credit: Charité | Arne SattlerOnce an infection is under control, the body normally uses

Updated on:April 22,2024 17

The double face of RNase as a treatment for systemic autoimmune diseases

by Osaka UniversityThe RNA-degrading enzyme enhances the function of immune complexes formed by autoantibodies against Ro/SSA and La/SSB antigens. Credit: Ryota Naito et al. JCI Insight 2023Syste

Updated on: April 22,2024 20

The double face of RNase as a treatment for systemic autoimmune diseases

by Osaka UniversityThe RNA-degrading enzyme enhances the function of immune complexes formed by autoantibodies against Ro/SSA and La/SSB antigens. Credit: Ryota Naito et al. JCI Insight 2023Syste

Updated on:April 22,2024 20

Detecting pathogens faster and more accurately by melting DNA

by Ioana Patringenaru,University of California - San DiegoResearchers use this chip to analyze the microbes present in whole blood samples. Credit: David Baillot/University of California San Die

Updated on: April 23,2024 0

Detecting pathogens faster and more accurately by melting DNA

by Ioana Patringenaru,University of California - San DiegoResearchers use this chip to analyze the microbes present in whole blood samples. Credit: David Baillot/University of California San Die

Updated on:April 23,2024 0

Scientists use blood test to track gene expression in the brain

by Kayt Sukel,Rice UniversityScan of mouse hippocampus and cortex, where the red signal derives from immunostaining for the synthetic marker developed by the Szablowski lab and the blue from the

Updated on: April 23,2024 0

Scientists use blood test to track gene expression in the brain

by Kayt Sukel,Rice UniversityScan of mouse hippocampus and cortex, where the red signal derives from immunostaining for the synthetic marker developed by the Szablowski lab and the blue from the

Updated on:April 23,2024 0

Oral interleukin-23-receptor antagonist peptide shows greater efficacy than placebo for plaque psoriasis

by Elana GotkineFor patients with moderate-to-severe plaque psoriasis, the interleukin-23-receptor antagonist peptide JNJ-77242113 shows greater efficacy than placebo, according to a study published i

Updated on: April 23,2024 17

Oral interleukin-23-receptor antagonist peptide shows greater efficacy than placebo for plaque psoriasis

by Elana GotkineFor patients with moderate-to-severe plaque psoriasis, the interleukin-23-receptor antagonist peptide JNJ-77242113 shows greater efficacy than placebo, according to a study published i

Updated on:April 23,2024 17

Parents scrambling after asthma inhaler Flovent removed from market

by Dennis ThompsonA popular asthma inhaler was discontinued on Jan. 1, and the business move has left families scrambling to find a replacement for their kids.Flovent was one of the most commonly pres

Updated on: April 23,2024 13

Parents scrambling after asthma inhaler Flovent removed from market

by Dennis ThompsonA popular asthma inhaler was discontinued on Jan. 1, and the business move has left families scrambling to find a replacement for their kids.Flovent was one of the most commonly pres

Updated on:April 23,2024 13

tRNA fragments are involved in poststroke immune reactions

by Goethe University Frankfurt am MainCredit: Pixabay/CC0 Public DomainSebastian Lobentanzer of Goethe University, Frankfurt, has been studying small RNA dynamics in various contexts using bioinf

Updated on: April 24,2024 14

tRNA fragments are involved in poststroke immune reactions

by Goethe University Frankfurt am MainCredit: Pixabay/CC0 Public DomainSebastian Lobentanzer of Goethe University, Frankfurt, has been studying small RNA dynamics in various contexts using bioinf

Updated on:April 24,2024 14

How T cells recognize infection or disease

by Monash UniversityResearch illuminating an elusive component of the adaptive immune system, how gamma delta T cells sense the metabolite-antigen presenting molecule MR1. Credit: (C) Dr Erica Ta

Updated on: April 24,2024 15

How T cells recognize infection or disease

by Monash UniversityResearch illuminating an elusive component of the adaptive immune system, how gamma delta T cells sense the metabolite-antigen presenting molecule MR1. Credit: (C) Dr Erica Ta

Updated on:April 24,2024 15

A turncoat protein allows viruses to ride roughshod in the liver, paving the way to cancer

by Delthia Ricks , Medical XpressImages showing the distribution of tagged STING and HA-HPN proteins in liver cells. Credit: F. Hsin et al.,Science Signaling(2021)Chronic viral infections

Updated on: April 24,2024 19

A turncoat protein allows viruses to ride roughshod in the liver, paving the way to cancer

by Delthia Ricks , Medical XpressImages showing the distribution of tagged STING and HA-HPN proteins in liver cells. Credit: F. Hsin et al.,Science Signaling(2021)Chronic viral infections

Updated on:April 24,2024 19

An unconventional ion channel

by Ludwig Maximilian University of MunichTRPML2 channels (green) on vacuolin-enlarged fast recycling vesicles (positive for the fast-recycling marker RAB4A (red)), permitting to microdissect thes

Updated on: April 24,2024 20

An unconventional ion channel

by Ludwig Maximilian University of MunichTRPML2 channels (green) on vacuolin-enlarged fast recycling vesicles (positive for the fast-recycling marker RAB4A (red)), permitting to microdissect thes

Updated on:April 24,2024 20