TLK protein inhibition activates the innate immune system

by Institute for Research in Biomedicine - IRBCancer cells with TLK inhibition show replication intermediates (green) at chromosome ends (red). Credit: IRB BarcelonaTousled-like kinases (TLKs) are a p

Updated on: April 24,2024

TLK protein inhibition activates the innate immune system

by Institute for Research in Biomedicine - IRBCancer cells with TLK inhibition show replication intermediates (green) at chromosome ends (red). Credit: IRB BarcelonaTousled-like kinases (TLKs) are a p

Updated on:April 24,2024

How a COVID-19 infection spurs antibodies against common colds

by The Scripps Research InstituteResearchers analyzed the structures of antibodies (colored) from healthy donors as the molecules bound to the spike protein from common coronaviruses like OC43 (s

Updated on: April 10,2024

How a COVID-19 infection spurs antibodies against common colds

by The Scripps Research InstituteResearchers analyzed the structures of antibodies (colored) from healthy donors as the molecules bound to the spike protein from common coronaviruses like OC43 (s

Updated on:April 10,2024

COVID-19 can cause severe inflammation in the brain

by Albert Ludwigs University of FreiburgGraphical Abstract. Credit:Immunity(2021). DOI: 10.1016/j.immuni.2021.06.002Both during and after infection with the Coronavirus SARS-CoV-2, pa

Updated on: April 10,2024

COVID-19 can cause severe inflammation in the brain

by Albert Ludwigs University of FreiburgGraphical Abstract. Credit:Immunity(2021). DOI: 10.1016/j.immuni.2021.06.002Both during and after infection with the Coronavirus SARS-CoV-2, pa

Updated on:April 10,2024

Suppressing graft-versus-host disease using immunosuppressive iPS cell-derived regulatory T cells

by Kyoto UniversityGraphical abstract. Credit:Cell Stem Cell(2024). DOI: 10.1016/j.stem.2024.05.004A recent study by a team led by Professor Shin Kaneko successfully induced regulator

Updated on: June 15,2024

Suppressing graft-versus-host disease using immunosuppressive iPS cell-derived regulatory T cells

by Kyoto UniversityGraphical abstract. Credit:Cell Stem Cell(2024). DOI: 10.1016/j.stem.2024.05.004A recent study by a team led by Professor Shin Kaneko successfully induced regulator

Updated on:June 15,2024

An antibody-drug combo to combat cancer

by Tokyo Medical and Dental UniversityCredit: Tokyo Medical and Dental UniversityLeukemias are debilitating cancers of the hematopoietic or blood-forming cells of the bone marrow. Now, researchers at

Updated on: May 05,2024

An antibody-drug combo to combat cancer

by Tokyo Medical and Dental UniversityCredit: Tokyo Medical and Dental UniversityLeukemias are debilitating cancers of the hematopoietic or blood-forming cells of the bone marrow. Now, researchers at

Updated on:May 05,2024

Inflammatory link discovered between arthritis and heart valve disease

by Walter and Eliza Hall InstituteAustralian researchers have used models to identify a potential link between excess production of inflammatory proteins that cause rheumatoid arthritis and the d

Updated on: March 24,2024

Inflammatory link discovered between arthritis and heart valve disease

by Walter and Eliza Hall InstituteAustralian researchers have used models to identify a potential link between excess production of inflammatory proteins that cause rheumatoid arthritis and the d

Updated on:March 24,2024

ATP-hydrolyzing ectoenzyme E-NTPD8 attenuates colitis

by Osaka UniversityE-NTPD8 in colonic epithelial cells maintains gut homeostasis through the hydrolysis of luminal ATP produced by commensal bacteria (left). An increased level of luminal ATP cau

Updated on: April 08,2024

ATP-hydrolyzing ectoenzyme E-NTPD8 attenuates colitis

by Osaka UniversityE-NTPD8 in colonic epithelial cells maintains gut homeostasis through the hydrolysis of luminal ATP produced by commensal bacteria (left). An increased level of luminal ATP cau

Updated on:April 08,2024

Inulin-gel-based oral immunotherapy may offer long-awaited treatment for food allergy sufferers

byUniversity of MichiganInulin gel/OVA protects mice against repeated allergen challenges with chicken egg white. Credit:Nature Materials(2024). DOI: 10.1038/s41563-024-01909-wA stud

Updated on: July 10,2024

Inulin-gel-based oral immunotherapy may offer long-awaited treatment for food allergy sufferers

byUniversity of MichiganInulin gel/OVA protects mice against repeated allergen challenges with chicken egg white. Credit:Nature Materials(2024). DOI: 10.1038/s41563-024-01909-wA stud

Updated on:July 10,2024

A key gene modifies regulatory T cells to fine-tune the immune response

by Salk InstituteA histology image showing inflammation in colon epithelium. Weakening of regulatory T cell function induces infiltration of immune cells (small blue dots) into colon epithelium (

Updated on: May 07,2024

A key gene modifies regulatory T cells to fine-tune the immune response

by Salk InstituteA histology image showing inflammation in colon epithelium. Weakening of regulatory T cell function induces infiltration of immune cells (small blue dots) into colon epithelium (

Updated on:May 07,2024

Low back pain? Don't blame the weather

by WileyCloud in Nepali sky. Credit: WikipediaAustralian researchers reveal that sudden, acute episodes of low back pain are not linked to weather conditions such as temperature, humidity, air pr

Updated on: March 24,2024

Low back pain? Don't blame the weather

by WileyCloud in Nepali sky. Credit: WikipediaAustralian researchers reveal that sudden, acute episodes of low back pain are not linked to weather conditions such as temperature, humidity, air pr

Updated on:March 24,2024

Macrophages produce heat from brown adipose tissue in response to cold, study reveals

by University of TsukubaGraphical abstract. Credit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113978Researchers from University of Tsukuba have elucidated the molecular mechanism

Updated on: March 27,2024

Macrophages produce heat from brown adipose tissue in response to cold, study reveals

by University of TsukubaGraphical abstract. Credit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113978Researchers from University of Tsukuba have elucidated the molecular mechanism

Updated on:March 27,2024

Dupilumab cuts exacerbations in late-onset asthma

(HealthDay)—Dupilumab is associated with significantly reduced severe exacerbation rates in patients with late-onset asthma with or without fixed airway obstruction, according to a study presented at

Updated on: April 15,2024

Dupilumab cuts exacerbations in late-onset asthma

(HealthDay)—Dupilumab is associated with significantly reduced severe exacerbation rates in patients with late-onset asthma with or without fixed airway obstruction, according to a study presented at

Updated on:April 15,2024