Inflammatory link discovered between arthritis and heart valve disease

by Walter and Eliza Hall InstituteAustralian researchers have used models to identify a potential link between excess production of inflammatory proteins that cause rheumatoid arthritis and the d

Updated on: March 24,2024

Inflammatory link discovered between arthritis and heart valve disease

by Walter and Eliza Hall InstituteAustralian researchers have used models to identify a potential link between excess production of inflammatory proteins that cause rheumatoid arthritis and the d

Updated on:March 24,2024

An antibody-drug combo to combat cancer

by Tokyo Medical and Dental UniversityCredit: Tokyo Medical and Dental UniversityLeukemias are debilitating cancers of the hematopoietic or blood-forming cells of the bone marrow. Now, researchers at

Updated on: May 05,2024

An antibody-drug combo to combat cancer

by Tokyo Medical and Dental UniversityCredit: Tokyo Medical and Dental UniversityLeukemias are debilitating cancers of the hematopoietic or blood-forming cells of the bone marrow. Now, researchers at

Updated on:May 05,2024

ATP-hydrolyzing ectoenzyme E-NTPD8 attenuates colitis

by Osaka UniversityE-NTPD8 in colonic epithelial cells maintains gut homeostasis through the hydrolysis of luminal ATP produced by commensal bacteria (left). An increased level of luminal ATP cau

Updated on: April 08,2024

ATP-hydrolyzing ectoenzyme E-NTPD8 attenuates colitis

by Osaka UniversityE-NTPD8 in colonic epithelial cells maintains gut homeostasis through the hydrolysis of luminal ATP produced by commensal bacteria (left). An increased level of luminal ATP cau

Updated on:April 08,2024

Inulin-gel-based oral immunotherapy may offer long-awaited treatment for food allergy sufferers

byUniversity of MichiganInulin gel/OVA protects mice against repeated allergen challenges with chicken egg white. Credit:Nature Materials(2024). DOI: 10.1038/s41563-024-01909-wA stud

Updated on: July 10,2024

Inulin-gel-based oral immunotherapy may offer long-awaited treatment for food allergy sufferers

byUniversity of MichiganInulin gel/OVA protects mice against repeated allergen challenges with chicken egg white. Credit:Nature Materials(2024). DOI: 10.1038/s41563-024-01909-wA stud

Updated on:July 10,2024

TLK protein inhibition activates the innate immune system

by Institute for Research in Biomedicine - IRBCancer cells with TLK inhibition show replication intermediates (green) at chromosome ends (red). Credit: IRB BarcelonaTousled-like kinases (TLKs) are a p

Updated on: April 24,2024

TLK protein inhibition activates the innate immune system

by Institute for Research in Biomedicine - IRBCancer cells with TLK inhibition show replication intermediates (green) at chromosome ends (red). Credit: IRB BarcelonaTousled-like kinases (TLKs) are a p

Updated on:April 24,2024

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on: April 16,2024

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on:April 16,2024

A key gene modifies regulatory T cells to fine-tune the immune response

by Salk InstituteA histology image showing inflammation in colon epithelium. Weakening of regulatory T cell function induces infiltration of immune cells (small blue dots) into colon epithelium (

Updated on: May 07,2024

A key gene modifies regulatory T cells to fine-tune the immune response

by Salk InstituteA histology image showing inflammation in colon epithelium. Weakening of regulatory T cell function induces infiltration of immune cells (small blue dots) into colon epithelium (

Updated on:May 07,2024

Lupus, rheumatoid arthritis tied to higher risk for adverse obstetric, birth outcomes

by Lori SolomonWomen with rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE) and their infants experience higher rates of adverse obstetric and birth outcomes, according to a study publis

Updated on: June 15,2024

Lupus, rheumatoid arthritis tied to higher risk for adverse obstetric, birth outcomes

by Lori SolomonWomen with rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE) and their infants experience higher rates of adverse obstetric and birth outcomes, according to a study publis

Updated on:June 15,2024

Study aims to unravel the genetic causes of osteoarthritis

by Wellcome Trust Sanger InstituteA hip with osteoarthritis. In an X-ray of a healthy hip, the heads of the hip bone have smooth, evenly curved surfaces and there is a 'gap' between the h

Updated on: March 28,2024

Study aims to unravel the genetic causes of osteoarthritis

by Wellcome Trust Sanger InstituteA hip with osteoarthritis. In an X-ray of a healthy hip, the heads of the hip bone have smooth, evenly curved surfaces and there is a 'gap' between the h

Updated on:March 28,2024

Women with rheumatoid arthritis more likely to achieve remission if they take sex hormones, finds research

by University of South AustraliaGraphical abstract. Credit:Rheumatology(2022). DOI: 10.1093/rheumatology/keac357A large study of women with rheumatoid arthritis has found that those t

Updated on: June 01,2024

Women with rheumatoid arthritis more likely to achieve remission if they take sex hormones, finds research

by University of South AustraliaGraphical abstract. Credit:Rheumatology(2022). DOI: 10.1093/rheumatology/keac357A large study of women with rheumatoid arthritis has found that those t

Updated on:June 01,2024

Anaphylaxis treatment remains confusing for patients, caregivers and emergency personnel, research finds

byAmerican College of Allergy, Asthma, and ImmunologyCredit: Unsplash/CC0 Public DomainAnaphylaxis can come on suddenly and without warning, and because its symptoms can be fatal, it is scary fo

Updated on: November 01,2024

Anaphylaxis treatment remains confusing for patients, caregivers and emergency personnel, research finds

byAmerican College of Allergy, Asthma, and ImmunologyCredit: Unsplash/CC0 Public DomainAnaphylaxis can come on suddenly and without warning, and because its symptoms can be fatal, it is scary fo

Updated on:November 01,2024

Low back pain? Don't blame the weather

by WileyCloud in Nepali sky. Credit: WikipediaAustralian researchers reveal that sudden, acute episodes of low back pain are not linked to weather conditions such as temperature, humidity, air pr

Updated on: March 24,2024

Low back pain? Don't blame the weather

by WileyCloud in Nepali sky. Credit: WikipediaAustralian researchers reveal that sudden, acute episodes of low back pain are not linked to weather conditions such as temperature, humidity, air pr

Updated on:March 24,2024