Immune receptor provides protective immunity against Group A Streptococcus

by Osaka UniversityFig. 1: The mechanism by which group A Streptococcus (GAS) evades the immune system. The immune receptor Mincle recognizes MGDG, an immunoactivating lipid present on GAS, and t

Updated on: April 16,2024

Immune receptor provides protective immunity against Group A Streptococcus

by Osaka UniversityFig. 1: The mechanism by which group A Streptococcus (GAS) evades the immune system. The immune receptor Mincle recognizes MGDG, an immunoactivating lipid present on GAS, and t

Updated on:April 16,2024

New study reveals specialization of immune cells in different tissues

byKarolinska InstitutetJohan Sandberg. Credit: Karolinska InstitutetA new study from Karolinska Institutet has mapped how MAIT cells, which play an important role in the body's defense again

Updated on: September 18,2024

New study reveals specialization of immune cells in different tissues

byKarolinska InstitutetJohan Sandberg. Credit: Karolinska InstitutetA new study from Karolinska Institutet has mapped how MAIT cells, which play an important role in the body's defense again

Updated on:September 18,2024

NSAIDs may worsen arthritis inflammation

by Radiological Society of North AmericaThe fat pad adjacent to the kneecap (Hoffa's fat pad, infrapatellar fat pad) can change in signal on MRI when the knee is inflamed. (A) Normal knee wit

Updated on: June 26,2024

NSAIDs may worsen arthritis inflammation

by Radiological Society of North AmericaThe fat pad adjacent to the kneecap (Hoffa's fat pad, infrapatellar fat pad) can change in signal on MRI when the knee is inflamed. (A) Normal knee wit

Updated on:June 26,2024

Weight loss predicts mortality in rheumatoid arthritis

(HealthDay)—Weight loss is a strong predictor of mortality in patients with rheumatoid arthritis (RA), according to a study published online June 26 inArthritis & Rheumatology.Joshua F. Bake

Updated on: April 08,2024

Weight loss predicts mortality in rheumatoid arthritis

(HealthDay)—Weight loss is a strong predictor of mortality in patients with rheumatoid arthritis (RA), according to a study published online June 26 inArthritis & Rheumatology.Joshua F. Bake

Updated on:April 08,2024

Brain activity linked to TNF inhibitor response in RA

Patients with rheumatoid arthritis who respond to tumor necrosis factor inhibitors show changes in activity in pain-related areas of the brain before clinical signs of improvement are observed, accord

Updated on: April 08,2024

Brain activity linked to TNF inhibitor response in RA

Patients with rheumatoid arthritis who respond to tumor necrosis factor inhibitors show changes in activity in pain-related areas of the brain before clinical signs of improvement are observed, accord

Updated on:April 08,2024

Anti-cancer virus fits tumor receptor like a 'key in a lock'

by Okinawa Institute of Science and TechnologyA cryo-EM map of the receptor decorated capsid in which a single protomer was replaced with the atomic model. Seneca Valley Virus capsid proteins are

Updated on: April 08,2024

Anti-cancer virus fits tumor receptor like a 'key in a lock'

by Okinawa Institute of Science and TechnologyA cryo-EM map of the receptor decorated capsid in which a single protomer was replaced with the atomic model. Seneca Valley Virus capsid proteins are

Updated on:April 08,2024

A better test for the tumor-targeting of CAR-T therapies

by Ludwig Institute for Cancer ResearchCredit: CC0 Public DomainLudwig Cancer Research scientists have developed a method to significantly improve the preclinical evaluation of chimeric antigen-r

Updated on: April 24,2024

A better test for the tumor-targeting of CAR-T therapies

by Ludwig Institute for Cancer ResearchCredit: CC0 Public DomainLudwig Cancer Research scientists have developed a method to significantly improve the preclinical evaluation of chimeric antigen-r

Updated on:April 24,2024

Mast cell levels may explain sex differences in osteoarthritis pain

by Hospital for Special SurgeryCredit: Pixabay/CC0 Public DomainInvestigators at Hospital for Special Surgery (HSS) have discovered that at the time of total knee replacement, women have signific

Updated on: April 17,2024

Mast cell levels may explain sex differences in osteoarthritis pain

by Hospital for Special SurgeryCredit: Pixabay/CC0 Public DomainInvestigators at Hospital for Special Surgery (HSS) have discovered that at the time of total knee replacement, women have signific

Updated on:April 17,2024

Rheumatoid arthritis finding may lead to new inflammation blockers

by Sara Tiner,Mayo ClinicCredit: Unsplash/CC0 Public DomainMayo Clinic researchers have linked the T cell dysfunction seen in rheumatoid arthritis with a metabolic deficiency, reported in a new&

Updated on: May 29,2024

Rheumatoid arthritis finding may lead to new inflammation blockers

by Sara Tiner,Mayo ClinicCredit: Unsplash/CC0 Public DomainMayo Clinic researchers have linked the T cell dysfunction seen in rheumatoid arthritis with a metabolic deficiency, reported in a new&

Updated on:May 29,2024

Novel checkpoint molecule of natural killer cell anti-tumor immunity revealed

by Li Yuan,Chinese Academy of SciencesFig. 1. TIPE2 expression correlates with NK cell maturation in both mice and humans.(A) TIPE2 expression of purified splenic NK cells from 2-, 4-, 6-, or 10

Updated on: April 20,2024

Novel checkpoint molecule of natural killer cell anti-tumor immunity revealed

by Li Yuan,Chinese Academy of SciencesFig. 1. TIPE2 expression correlates with NK cell maturation in both mice and humans.(A) TIPE2 expression of purified splenic NK cells from 2-, 4-, 6-, or 10

Updated on:April 20,2024

Online therapy aids the isolated, immunosuppressed in pandemic

by Noah Fromson,University of MichiganCredit: CC0 Public DomainPeople with a rare autoimmune disease, who likely experience more serious isolation during a global pandemic, saw their anxiety and

Updated on: March 24,2024

Online therapy aids the isolated, immunosuppressed in pandemic

by Noah Fromson,University of MichiganCredit: CC0 Public DomainPeople with a rare autoimmune disease, who likely experience more serious isolation during a global pandemic, saw their anxiety and

Updated on:March 24,2024

PFAS shown to reduce the activity of immune cells

by Helmholtz Association of German Research CentresGraphical abstract. Credit:Chemosphere(2023). DOI: 10.1016/j.chemosphere.2023.139204PFAS are used in many everyday products. This is

Updated on: April 20,2024

PFAS shown to reduce the activity of immune cells

by Helmholtz Association of German Research CentresGraphical abstract. Credit:Chemosphere(2023). DOI: 10.1016/j.chemosphere.2023.139204PFAS are used in many everyday products. This is

Updated on:April 20,2024