Blocking the longevity gene S6K1 extends lifespan in mice by reducing inflammation

by Medical Research Council (MRC) Laboratory of Medical SciencesS6K1 deletion attenuates age-related liver pathology.a, Experimental scheme.S6K1WT and KO mice were aged for 600 d to

Updated on: September 07,2024

Blocking the longevity gene S6K1 extends lifespan in mice by reducing inflammation

by Medical Research Council (MRC) Laboratory of Medical SciencesS6K1 deletion attenuates age-related liver pathology.a, Experimental scheme.S6K1WT and KO mice were aged for 600 d to

Updated on:September 07,2024

Rheumatoid arthritis drug not linked to specific birth defects

The rheumatoid arthritis drug leflunomide is not a major cause of birth defects in women who inadvertently become pregnant while taking the drug, although pregnancy should be avoided, according to a s

Updated on: March 24,2024

Rheumatoid arthritis drug not linked to specific birth defects

The rheumatoid arthritis drug leflunomide is not a major cause of birth defects in women who inadvertently become pregnant while taking the drug, although pregnancy should be avoided, according to a s

Updated on:March 24,2024

Increased insulin resistance in rheumatoid arthritis

(HealthDay)—Patients with rheumatoid arthritis (RA) have elevated insulin resistance (IR), but this is not associated with increased atherosclerosis risk, according to a study published online Dec. 10

Updated on: April 08,2024

Increased insulin resistance in rheumatoid arthritis

(HealthDay)—Patients with rheumatoid arthritis (RA) have elevated insulin resistance (IR), but this is not associated with increased atherosclerosis risk, according to a study published online Dec. 10

Updated on:April 08,2024

Epigenetics alters genes in rheumatoid arthritis

by University of California - San DiegoIn this artist's rendering, a DNA molecule is methylated on both strands at the center cytosine. DNA methylation plays an important role in epigenetic g

Updated on: March 24,2024

Epigenetics alters genes in rheumatoid arthritis

by University of California - San DiegoIn this artist's rendering, a DNA molecule is methylated on both strands at the center cytosine. DNA methylation plays an important role in epigenetic g

Updated on:March 24,2024

New mechanism fueling brain metastasis discovered at Wistar

by The Wistar InstituteDr. Qing Chen of The Wistar Institute Credit: The Wistar InstituteScientists at The Wistar Institute described a novel mechanism through which astrocytes, the most abundant

Updated on: May 05,2024

New mechanism fueling brain metastasis discovered at Wistar

by The Wistar InstituteDr. Qing Chen of The Wistar Institute Credit: The Wistar InstituteScientists at The Wistar Institute described a novel mechanism through which astrocytes, the most abundant

Updated on:May 05,2024

Dupilumab cuts exacerbations in late-onset asthma

(HealthDay)—Dupilumab is associated with significantly reduced severe exacerbation rates in patients with late-onset asthma with or without fixed airway obstruction, according to a study presented at

Updated on: April 15,2024

Dupilumab cuts exacerbations in late-onset asthma

(HealthDay)—Dupilumab is associated with significantly reduced severe exacerbation rates in patients with late-onset asthma with or without fixed airway obstruction, according to a study presented at

Updated on:April 15,2024

TLK protein inhibition activates the innate immune system

by Institute for Research in Biomedicine - IRBCancer cells with TLK inhibition show replication intermediates (green) at chromosome ends (red). Credit: IRB BarcelonaTousled-like kinases (TLKs) are a p

Updated on: April 24,2024

TLK protein inhibition activates the innate immune system

by Institute for Research in Biomedicine - IRBCancer cells with TLK inhibition show replication intermediates (green) at chromosome ends (red). Credit: IRB BarcelonaTousled-like kinases (TLKs) are a p

Updated on:April 24,2024

Balance between sleep and exercise may be key to help osteoarthritis patients manage pain

by University of MichiganCredit: CC0 Public DomainIt may shoot through the hands while typing or flare in the knees when getting out of the car. Wherever the pain, over 32 million Americans livin

Updated on: May 08,2024

Balance between sleep and exercise may be key to help osteoarthritis patients manage pain

by University of MichiganCredit: CC0 Public DomainIt may shoot through the hands while typing or flare in the knees when getting out of the car. Wherever the pain, over 32 million Americans livin

Updated on:May 08,2024

Subclinical atherosclerosis noted in diffuse scleroderma

Patients with diffuse systemic sclerosis, without any clinical evidence of cardiovascular disease, have indicators of subclinical atherosclerosis, according to a study published online Aug. 16 in&nbsp

Updated on: March 24,2024

Subclinical atherosclerosis noted in diffuse scleroderma

Patients with diffuse systemic sclerosis, without any clinical evidence of cardiovascular disease, have indicators of subclinical atherosclerosis, according to a study published online Aug. 16 in&nbsp

Updated on:March 24,2024

Higher incidence of edema with bacteriuria in C1-INH-HAE

(HealthDay)—For patients with hereditary angioedema due to C1-inhibitor deficiency (C1-INH-HAE), those with bacteriuria have a higher number of edematous attacks, according to a study published online

Updated on: April 08,2024

Higher incidence of edema with bacteriuria in C1-INH-HAE

(HealthDay)—For patients with hereditary angioedema due to C1-inhibitor deficiency (C1-INH-HAE), those with bacteriuria have a higher number of edematous attacks, according to a study published online

Updated on:April 08,2024

Study of infants and young children shows that offspring develop normally in mothers with rheumatic disease

by European League Against Rheumatism (EULAR)Credit: CC0 Public DomainAnkylosing spondylitis (AS) is a complex chronic inflammatory disease of the spine with involvement of the sacroiliac joints. Over

Updated on: June 26,2024

Study of infants and young children shows that offspring develop normally in mothers with rheumatic disease

by European League Against Rheumatism (EULAR)Credit: CC0 Public DomainAnkylosing spondylitis (AS) is a complex chronic inflammatory disease of the spine with involvement of the sacroiliac joints. Over

Updated on:June 26,2024

Study finds holding methotrexate for one week after flu vaccine may be as effective as a two-week hold

by American College of RheumatologyStudy design and vaccine response at 4 and 16 weeks. (A) Study design. (B) The percentage of patients achieving a satisfactory vaccine response, defined as ≥4-f

Updated on: July 02,2024

Study finds holding methotrexate for one week after flu vaccine may be as effective as a two-week hold

by American College of RheumatologyStudy design and vaccine response at 4 and 16 weeks. (A) Study design. (B) The percentage of patients achieving a satisfactory vaccine response, defined as ≥4-f

Updated on:July 02,2024