TAp63: A new protein drug target for rheumatoid arthritis

by Chiba UniversityGraphical abstract. Credit:JCI Insight(2023). DOI: 10.1172/jci.insight.164778Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint deterioration. The

Updated on: May 08,2024

TAp63: A new protein drug target for rheumatoid arthritis

by Chiba UniversityGraphical abstract. Credit:JCI Insight(2023). DOI: 10.1172/jci.insight.164778Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint deterioration. The

Updated on:May 08,2024

Prevalence of knee OA lower with menopausal hormone therapy

(HealthDay)—For postmenopausal women, the prevalence of knee osteoarthritis is lower with menopausal hormone therapy (MHT) use, according to a study published online Dec. 21 inMenopause.Jae Hyun

Updated on: May 26,2024

Prevalence of knee OA lower with menopausal hormone therapy

(HealthDay)—For postmenopausal women, the prevalence of knee osteoarthritis is lower with menopausal hormone therapy (MHT) use, according to a study published online Dec. 21 inMenopause.Jae Hyun

Updated on:May 26,2024

Fatigue common even with early rheumatoid arthritis

(HealthDay)—Fatigue is prevalent and persistent in early rheumatoid arthritis (RA), according to a study published online Dec. 27 inRheumatology.Onosi Sylvia Ifesemen, M.B.B.S., from the Univers

Updated on: June 17,2024

Fatigue common even with early rheumatoid arthritis

(HealthDay)—Fatigue is prevalent and persistent in early rheumatoid arthritis (RA), according to a study published online Dec. 27 inRheumatology.Onosi Sylvia Ifesemen, M.B.B.S., from the Univers

Updated on:June 17,2024

CrAss viral content: When it's in your gut, it might be good for your health

by Osaka UniversityFig.1 Schematic illustration of the study design. Credit: Yoshihiko Tomofuji et al.,Annals of the Rheumatic DiseasesAutoimmune diseases are conditions in which the immune

Updated on: April 07,2024

CrAss viral content: When it's in your gut, it might be good for your health

by Osaka UniversityFig.1 Schematic illustration of the study design. Credit: Yoshihiko Tomofuji et al.,Annals of the Rheumatic DiseasesAutoimmune diseases are conditions in which the immune

Updated on:April 07,2024

Here's why B cells benefit from booster shots

byRockefeller UniversityRecall germinal centers formed in response to a secondary infection generate a second line of defense, rebuffing memory B cells in favor of training naive ones. Credit: R

Updated on: October 10,2024

Here's why B cells benefit from booster shots

byRockefeller UniversityRecall germinal centers formed in response to a secondary infection generate a second line of defense, rebuffing memory B cells in favor of training naive ones. Credit: R

Updated on:October 10,2024

Inactivity and obesity relate to cognitive impairment in lupus

(HealthDay) -- Physical inactivity and obesity are associated with impaired cognitive function, especially executive functions, in women with systemic lupus erythematosus (SLE), according to research

Updated on: April 08,2024

Inactivity and obesity relate to cognitive impairment in lupus

(HealthDay) -- Physical inactivity and obesity are associated with impaired cognitive function, especially executive functions, in women with systemic lupus erythematosus (SLE), according to research

Updated on:April 08,2024

A bacterial toxin turning cells into swiss cheese

by Kanazawa UniversityResearchers from Kanazawa University developed a novel tool to study how the innate immune system fights bacterial toxins. They purified the pore-forming toxin Monalysin fro

Updated on: May 05,2024

A bacterial toxin turning cells into swiss cheese

by Kanazawa UniversityResearchers from Kanazawa University developed a novel tool to study how the innate immune system fights bacterial toxins. They purified the pore-forming toxin Monalysin fro

Updated on:May 05,2024

New study points to a better way to ward off asthma triggers

by La Jolla Institute for ImmunologyLeft: Lung tissue of untreated mice. Right: Lung tissue of mice treated with antibodies blocking OX40L and CD30L. Credit: Dr. Gurupreet Sethi, La Jolla Institu

Updated on: May 05,2024

New study points to a better way to ward off asthma triggers

by La Jolla Institute for ImmunologyLeft: Lung tissue of untreated mice. Right: Lung tissue of mice treated with antibodies blocking OX40L and CD30L. Credit: Dr. Gurupreet Sethi, La Jolla Institu

Updated on:May 05,2024

New vaccine protects from widespread, costly infection, mice study shows

by American Society for MicrobiologyCredit: CC0 Public DomainA newly developed experimental vaccine was more than eighty percent effective in protecting mice from succumbing toStaphylococcu

Updated on: May 08,2024

New vaccine protects from widespread, costly infection, mice study shows

by American Society for MicrobiologyCredit: CC0 Public DomainA newly developed experimental vaccine was more than eighty percent effective in protecting mice from succumbing toStaphylococcu

Updated on:May 08,2024

Key discovery in psoriatic arthritis points way for developing targeted treatments

by University of OxfordCredit: Unsplash/CC0 Public DomainA new study has revealed psoriatic arthritis may be activated by the same trigger in different patients. Researchers from the University o

Updated on: June 15,2024

Key discovery in psoriatic arthritis points way for developing targeted treatments

by University of OxfordCredit: Unsplash/CC0 Public DomainA new study has revealed psoriatic arthritis may be activated by the same trigger in different patients. Researchers from the University o

Updated on:June 15,2024

Bone drug may be beneficial for knee osteoarthritis

by Boston University School of MedicineCredit: CC0 Public DomainBisphosphonates (a class of drugs that prevent the loss of bone density and used to treat osteoporosis and similar diseases) appear

Updated on: April 17,2024

Bone drug may be beneficial for knee osteoarthritis

by Boston University School of MedicineCredit: CC0 Public DomainBisphosphonates (a class of drugs that prevent the loss of bone density and used to treat osteoporosis and similar diseases) appear

Updated on:April 17,2024

GABA released by B-cells blunts the immune response to tumors

by RIKENFig. 1: Metabolic remodeling of immunized LNs and B cell-dependent GABA production. a–e, Mice were injected in the foot pad with OVA + CFA, and iLNs and cLNs were collected for metabolite

Updated on: April 08,2024

GABA released by B-cells blunts the immune response to tumors

by RIKENFig. 1: Metabolic remodeling of immunized LNs and B cell-dependent GABA production. a–e, Mice were injected in the foot pad with OVA + CFA, and iLNs and cLNs were collected for metabolite

Updated on:April 08,2024