Antibodies in blood soon after COVID-19 onset may predict severity

by Bruce Goldman,Stanford University Medical CenterAn illustration of antlbodies surrounding a virus.Antibodies are proteins shaped, roughly speaking, like two-branched trees. They’re prod

Updated on: April 10,2024

Antibodies in blood soon after COVID-19 onset may predict severity

by Bruce Goldman,Stanford University Medical CenterAn illustration of antlbodies surrounding a virus.Antibodies are proteins shaped, roughly speaking, like two-branched trees. They’re prod

Updated on:April 10,2024

A 'backpack' full of multiple sclerosis therapy

by Benjamin Boettner,Harvard UniversityShown on the left, is an immunofluorescence image of a monocyte with its outer cell membrane stained in green and nucleus stained in blue, and to which the

Updated on: April 24,2024

A 'backpack' full of multiple sclerosis therapy

by Benjamin Boettner,Harvard UniversityShown on the left, is an immunofluorescence image of a monocyte with its outer cell membrane stained in green and nucleus stained in blue, and to which the

Updated on:April 24,2024

TNF inhibitors may not modify polyarticular JIA disease process

(HealthDay)—For children with polyarticular juvenile idiopathic arthritis (JIA), discontinuing medications is challenging, with high relapse rates, especially after discontinuation of tumor necrosis f

Updated on: April 08,2024

TNF inhibitors may not modify polyarticular JIA disease process

(HealthDay)—For children with polyarticular juvenile idiopathic arthritis (JIA), discontinuing medications is challenging, with high relapse rates, especially after discontinuation of tumor necrosis f

Updated on:April 08,2024

GABA released by B-cells blunts the immune response to tumors

by RIKENFig. 1: Metabolic remodeling of immunized LNs and B cell-dependent GABA production. a–e, Mice were injected in the foot pad with OVA + CFA, and iLNs and cLNs were collected for metabolite

Updated on: April 08,2024

GABA released by B-cells blunts the immune response to tumors

by RIKENFig. 1: Metabolic remodeling of immunized LNs and B cell-dependent GABA production. a–e, Mice were injected in the foot pad with OVA + CFA, and iLNs and cLNs were collected for metabolite

Updated on:April 08,2024

TAp63: A new protein drug target for rheumatoid arthritis

by Chiba UniversityGraphical abstract. Credit:JCI Insight(2023). DOI: 10.1172/jci.insight.164778Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint deterioration. The

Updated on: May 08,2024

TAp63: A new protein drug target for rheumatoid arthritis

by Chiba UniversityGraphical abstract. Credit:JCI Insight(2023). DOI: 10.1172/jci.insight.164778Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint deterioration. The

Updated on:May 08,2024

Here's why B cells benefit from booster shots

byRockefeller UniversityRecall germinal centers formed in response to a secondary infection generate a second line of defense, rebuffing memory B cells in favor of training naive ones. Credit: R

Updated on: October 10,2024

Here's why B cells benefit from booster shots

byRockefeller UniversityRecall germinal centers formed in response to a secondary infection generate a second line of defense, rebuffing memory B cells in favor of training naive ones. Credit: R

Updated on:October 10,2024

Methotrexate improves function in people with knee OA after three months

by American College of RheumatologyCredit: CC0 Public DomainA new study presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that after three months of t

Updated on: May 13,2024

Methotrexate improves function in people with knee OA after three months

by American College of RheumatologyCredit: CC0 Public DomainA new study presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that after three months of t

Updated on:May 13,2024

A bacterial toxin turning cells into swiss cheese

by Kanazawa UniversityResearchers from Kanazawa University developed a novel tool to study how the innate immune system fights bacterial toxins. They purified the pore-forming toxin Monalysin fro

Updated on: May 05,2024

A bacterial toxin turning cells into swiss cheese

by Kanazawa UniversityResearchers from Kanazawa University developed a novel tool to study how the innate immune system fights bacterial toxins. They purified the pore-forming toxin Monalysin fro

Updated on:May 05,2024

Innovative software improves chronic rheumatic disease care

(HealthDay)—For patients with chronic rheumatic disease, innovative software that aggregates, stores, and displays information can improve quality of care, according to research published online Nov.

Updated on: April 08,2024

Innovative software improves chronic rheumatic disease care

(HealthDay)—For patients with chronic rheumatic disease, innovative software that aggregates, stores, and displays information can improve quality of care, according to research published online Nov.

Updated on:April 08,2024

SARS-CoV-2 disrupts timing of immune response

by Charité - Universitätsmedizin BerlinAssay to detect the biochemical messenger TGFβ (COVID-19 research). Credit: Charité | Arne SattlerOnce an infection is under control, the body normally uses

Updated on: April 22,2024

SARS-CoV-2 disrupts timing of immune response

by Charité - Universitätsmedizin BerlinAssay to detect the biochemical messenger TGFβ (COVID-19 research). Credit: Charité | Arne SattlerOnce an infection is under control, the body normally uses

Updated on:April 22,2024

Scientists discover two cellular defects appear to drive disease in lupus

byNorthwestern UniversityCredit: Pixabay/CC0 Public DomainNorthwestern Medicine and Brigham and Women's Hospital scientists have discovered a molecular defect that promotes the pathologic im

Updated on: July 11,2024

Scientists discover two cellular defects appear to drive disease in lupus

byNorthwestern UniversityCredit: Pixabay/CC0 Public DomainNorthwestern Medicine and Brigham and Women's Hospital scientists have discovered a molecular defect that promotes the pathologic im

Updated on:July 11,2024

Differences in T cells' functional state determine resistance to cancer therapy

by Massachusetts Institute of TechnologyThe researchers took this image of a tumor using immunofluorescence, a technique that allows them to stain tissue sections with fluorescently-labeled antib

Updated on: May 08,2024

Differences in T cells' functional state determine resistance to cancer therapy

by Massachusetts Institute of TechnologyThe researchers took this image of a tumor using immunofluorescence, a technique that allows them to stain tissue sections with fluorescently-labeled antib

Updated on:May 08,2024