Cryo-EM imaging of STING protein reveals new binding pocket

by UniversityofTexasSouthwesternMedicalCenterThe synthetic drug-like compound (magenta spheres at the bottom) targets a hidden pocket in STING. This pocket is located at

Updated on: May 07,2024 12

Cryo-EM imaging of STING protein reveals new binding pocket

by UniversityofTexasSouthwesternMedicalCenterThe synthetic drug-like compound (magenta spheres at the bottom) targets a hidden pocket in STING. This pocket is located at

Updated on:May 07,2024 12

New advice on arthritis drugs

by Flinders UniversityCredit: CC0 Public DomainNew research evaluating the drugs commonly used by rheumatoid arthritis patients suggests two combinations could reduce the risk of heart attack and

Updated on: June 17,2024 7

New advice on arthritis drugs

by Flinders UniversityCredit: CC0 Public DomainNew research evaluating the drugs commonly used by rheumatoid arthritis patients suggests two combinations could reduce the risk of heart attack and

Updated on:June 17,2024 7

Online therapy aids the isolated, immunosuppressed in pandemic

by Noah Fromson,University of MichiganCredit: CC0 Public DomainPeople with a rare autoimmune disease, who likely experience more serious isolation during a global pandemic, saw their anxiety and

Updated on: March 24,2024 17

Online therapy aids the isolated, immunosuppressed in pandemic

by Noah Fromson,University of MichiganCredit: CC0 Public DomainPeople with a rare autoimmune disease, who likely experience more serious isolation during a global pandemic, saw their anxiety and

Updated on:March 24,2024 17

Chemical stimuli can support growing of stable cartilage cells

by Umea UniversityRho-kinase inhibition cause disappearance of cellular adhesion sites. The colors of the figure shows the staining for actin stress fibers (red), adhesion plaques-related vinculi

Updated on: May 08,2024 8

Chemical stimuli can support growing of stable cartilage cells

by Umea UniversityRho-kinase inhibition cause disappearance of cellular adhesion sites. The colors of the figure shows the staining for actin stress fibers (red), adhesion plaques-related vinculi

Updated on:May 08,2024 8

New 3-D imaging analysis technique could lead to improved arthritis treatment

by University of CambridgeJoint space in hip, knee and ankle joints as analyzed by the JSM algorithm. Credit: Tom TurmezeiAn algorithm to monitor the joints of patients with arthritis, which coul

Updated on: May 29,2024 6

New 3-D imaging analysis technique could lead to improved arthritis treatment

by University of CambridgeJoint space in hip, knee and ankle joints as analyzed by the JSM algorithm. Credit: Tom TurmezeiAn algorithm to monitor the joints of patients with arthritis, which coul

Updated on:May 29,2024 6

Among allergic conditions, food allergy found to have highest risk of developing eosinophilic esophagitis

byAmerican College of Allergy, Asthma, and ImmunologyCredit: Unsplash/CC0 Public DomainEosinophilic esophagitis (EoE), a disorder of the esophagus, is increasingly recognized as a major cause of

Updated on: November 01,2024 0

Among allergic conditions, food allergy found to have highest risk of developing eosinophilic esophagitis

byAmerican College of Allergy, Asthma, and ImmunologyCredit: Unsplash/CC0 Public DomainEosinophilic esophagitis (EoE), a disorder of the esophagus, is increasingly recognized as a major cause of

Updated on:November 01,2024 0

Recognizing young people's perspectives in inflammatory arthritis

by EULARFigure 1 Example outlining the different steps of the analysis from a meaning unit to lower and higher level concepts. PROMs, patient-reported outcome measures.Inflammatory arthritis is the na

Updated on: May 26,2024 7

Recognizing young people's perspectives in inflammatory arthritis

by EULARFigure 1 Example outlining the different steps of the analysis from a meaning unit to lower and higher level concepts. PROMs, patient-reported outcome measures.Inflammatory arthritis is the na

Updated on:May 26,2024 7

GABA released by B-cells blunts the immune response to tumors

by RIKENFig. 1: Metabolic remodeling of immunized LNs and B cell-dependent GABA production. a–e, Mice were injected in the foot pad with OVA + CFA, and iLNs and cLNs were collected for metabolite

Updated on: April 08,2024 15

GABA released by B-cells blunts the immune response to tumors

by RIKENFig. 1: Metabolic remodeling of immunized LNs and B cell-dependent GABA production. a–e, Mice were injected in the foot pad with OVA + CFA, and iLNs and cLNs were collected for metabolite

Updated on:April 08,2024 15

How IL-33 plays a key role in enabling the marathon runners of the immune system

by University of BaselGraphical abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.01.029When it comes to chronic infections and cancer, a particular type of immune cell play

Updated on: April 16,2024 10

How IL-33 plays a key role in enabling the marathon runners of the immune system

by University of BaselGraphical abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.01.029When it comes to chronic infections and cancer, a particular type of immune cell play

Updated on:April 16,2024 10

Five genes tied to osteoarthritis progression

(HealthDay)—Five genes may serve as biomarkers for osteoarthritis (OA) progression, according to a study published online Feb. 2 in theInternational Journal of Rheumatic Diseases.Beiyue Wang, fr

Updated on: April 07,2024 20

Five genes tied to osteoarthritis progression

(HealthDay)—Five genes may serve as biomarkers for osteoarthritis (OA) progression, according to a study published online Feb. 2 in theInternational Journal of Rheumatic Diseases.Beiyue Wang, fr

Updated on:April 07,2024 20

Early therapy for rheumatoid arthritis may slow heart disease

(HealthDay)—Disease-modifying antirheumatic drug (DMARD) therapy for rheumatoid arthritis (RA) treatment also cuts cardiovascular disease (CVD) risk, according to a study published online Aug. 28 in t

Updated on: May 29,2024 5

Early therapy for rheumatoid arthritis may slow heart disease

(HealthDay)—Disease-modifying antirheumatic drug (DMARD) therapy for rheumatoid arthritis (RA) treatment also cuts cardiovascular disease (CVD) risk, according to a study published online Aug. 28 in t

Updated on:May 29,2024 5

Study suggests parents' understanding of atopic dermatitis may influence child's diet

byAmerican College of Allergy, Asthma, and ImmunologyCredit: CC0 Public DomainParents of children with atopic dermatitis (AD, also called eczema) know that the allergic condition can mean a heig

Updated on: October 30,2024 0

Study suggests parents' understanding of atopic dermatitis may influence child's diet

byAmerican College of Allergy, Asthma, and ImmunologyCredit: CC0 Public DomainParents of children with atopic dermatitis (AD, also called eczema) know that the allergic condition can mean a heig

Updated on:October 30,2024 0